Catalog No.
YHJ47401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met157-Pro296
Predicted molecular weight
18.72 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99836
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MYD88, Myeloid differentiation primary response protein MyD88
In silico analysis of Triphala-derived polyphenols as inhibitors of TIR-TIR homodimerization in the inflammatory pathway., PMID:40510601
Upregulation of TLR-MYD88 signaling, stem cell genes, and Klotho mediates sepsis-associated myocardial inflammation., PMID:40504431
Respiratory Syncytial Virus Infection Disrupts Airway Epithelial Barriers via IL-33/ST2/MyD88 Signaling Axis., PMID:40497542
Syringetin ameliorates thallium sulphate induced renal dysfunction via regulating Nrf2/Keap-1, TLR4/HMGB1/RAGE and NF-κB pathway., PMID:40494130
LncRNA ZFAS1 promotes the transformation from prostatitis to prostate cancer via myddosome assembly-mediated activation of NF-κB signaling., PMID:40493092
Anti-inflammatory effects of Rehmannia glutinosa polysaccharide on LPS-induced acute liver injury in mice and related underlying mechanisms., PMID:40484254
Development of 9-cinnamyl-9H-purine derivatives as potent anticancer agents through inactivation of NF-κb/p65 and p-STAT1 signaling pathways: Discovery of a new template for adenosine receptor., PMID:40480105
Proteomic analysis of dysregulated pulmonary protein expression and potential pathways in broilers induced by particulate matter exposure in poultry houses., PMID:40479768
β‑elemene attenuates IRI‑AKI by inhibiting inflammation and apoptosis via suppression of the TLR4/MyD88/NF‑κB/MAPK signal axis activation., PMID:40476551
Clinical outcomes of newly diagnosed PCNSL treated with rituximab-methotrexate-cytarabine with or without ibrutinib: a retrospective study., PMID:40475774
Efficacy and safety of a novel CD19, CD22 dual-targeted fully human loop bi-CAR-T for the treatment of relapsed/refractory B cell non-Hodgkin lymphoma., PMID:40474279
Rhein-induced apoptosis in colorectal cancer cell lines: A mechanistic study of the myeloid differentiation primary response gene 88/toll-like receptor 4/nuclear factor kappa-B signaling pathway., PMID:40469706
Baihu Guizhi decoction alleviates inflammation in rats with acute gouty arthritis by targeting miR-17-5p to regulate the TLR4/Myd88/NF-κB signaling pathway., PMID:40466439
Functional Foods Alleviate Behavioral Alterations and Improve GABAergic System Regulating TLR-4/NF-κB Axis in Valproic-Induced Autism., PMID:40462659
[Polysaccharide extract PCP1 from Polygonatum cyrtonema ameliorates cerebral ischemia-reperfusion injury in rats by inhibiting TLR4/NLRP3 pathway]., PMID:40461201
MyD88 knockdown by RNAi prevents bacterial stimulation of tubeworm metamorphosis., PMID:40455987
Alleviation of dextran sulfate sodium (DSS)-induced colitis in mice through the antioxidative effects of muscone via the MyD88/p38 MAPK signalling pathway., PMID:40452925
The activation of the NF-κB p65/PD-L1 signaling pathway in AIDS-related PCNSL is related to TNF-α and IFN-γ but not to MYD88 and CD79B mutations., PMID:40450975
Astragaloside IV ameliorates Parkinson's disease by inhibiting TLR4/NF-κB-dependent neuroinflammation., PMID:40449268
Gamma -aminobutyric acid ameliorates neurological impairments in type 1 diabetes mellitus mice by regulating the "gut flora-LPS-TLR4-NF-ΚB" signalling Axis., PMID:40448159
Endothelial HSPA12B regulates myocardial monocyte infiltration and inflammatory activity after myocardial infarction., PMID:40443679
Interleukin-37 modulates microglial phenotype and inhibits inflammatory response via the MyD88/NF-κB pathway in lipopolysaccharide-induced neuroinflammation., PMID:40439750
An aegerolysin-like protein from Heliothis virescens ascovirus 3h (HvAV-3h) shows immune suppression and antibacterial activity., PMID:40439700
SARM1: a key multifaceted component in immunoregulation, inflammation and neurodegeneration., PMID:40433385
Cardio-Renal and Systemic Effects of SGLT2i Dapagliflozin on Short-Term Anthracycline and HER-2-Blocking Agent Therapy-Induced Cardiotoxicity., PMID:40427493
Alleviating the Effect of Branched-Chain Fatty Acids on the Lipopolysaccharide-Induced Inflammatory Response in Calf Small Intestinal Epithelial Cells., PMID:40427489
Weaning Stress Aggravates Defense Response and the Burden of Protein Metabolism in Low-Birth-Weight Piglets., PMID:40427247
Urotensin-II receptor contributes to the pro-inflammatory TLR4/MyD88/NF-κB/iNOS/NO pathway-mediated cardiovascular response to systemic lipopolysaccharide challenge in a septic shock model in rats., PMID:40418546
The effect of anthocyanin extract from Lycium ruthenicum Murray on intestinal barrier function in Bamei ternary pigs., PMID:40410595
Selenoprotein K-dependent MyD88 palmitoylation promotes hepatic metaflammation in high-fat diet fed mice., PMID:40409695
Response of Litopenaeus vannamei to dietary Isothiocyanate: Growth, biochemistry, immunity and gene expression related to hepatopancreas and intestinal health., PMID:40404028
Inhibition of Farnesoid-x-receptor signaling during abdominal sepsis by dysbiosis exacerbates gut barrier dysfunction., PMID:40399878
Cornel iridoid glycosides exerted neuroprotective effects against cerebral ischemia/reperfusion injury in rats via inhibiting TLR4/MyD88/NF-κB pathway., PMID:40398794
Integrated proteomics and phosphoproteomics profiling dynamic signaling networks underlying two distinct types of macrophage activation., PMID:40398355
Clustering Based on Innate Immunity Reveals Differential Dysregulation Based on Disease Severity in Myelodysplastic Neoplasms., PMID:40397075
Antigen/adjuvant-free liposome induces adjuvant effects for enhancing cancer immunotherapy., PMID:40395757
Platycodon grandiflorum Attenuates Non-Alcoholic Fatty Liver Disease in Rats Through Regulating Inflammatory Response via PPARγ and TLR4/NF-κB Signaling Pathway., PMID:40395044
Electroacupuncture ameliorates cartilage damage in a rat model of knee osteoarthritis and regulates expression of miRNAs and the TLR4/NF-κB pathway., PMID:40390302
Paclitaxel, interferons and functional reprogramming of tumor-associated macrophages in optimized chemo-immunotherapy., PMID:40389375
Shen Shuai II Recipe alleviates renal fibrosis in chronic kidney disease by improving of hypoxia and inhibition of TLR4/MyD88/NF-κB/NLRP3 pathway., PMID:40384385
Salvianolic acid B exerts cerebroprotective effects after traumatic brain injury via Nrf2-dependent antioxidant and anti-inflammatory cascades., PMID:40383364
Qingfei Litan decoction alleviated Klebsiella pneumoniae-induced pneumonia by targeting the TLR4/MyD88/NF-κB axis via miR-146a-5p., PMID:40378935
Suppressing TLR4 alleviates cerebral injury in heatstroke rats through the modulation of microglial polarization., PMID:40376840
A Study on the Anti-Inflammatory and Antibacterial Effects of Huanglian Jiedu Decoction in the Treatment of Pressure Injuries., PMID:40370231
Mechanistic role of pyroptosis in Kawasaki disease: An integrative bioinformatics analysis of immune dysregulation, machine learning-based biomarker discovery, WGCNA, and drug repurposing insights., PMID:40367231
Biological mechanisms and therapeutic prospects of interleukin-33 in pathogenesis and treatment of allergic disease., PMID:40355878
Diagnostic approach to leptomeningeal involvement in diffuse large B-cell lymphoma., PMID:40354563
[Effect and mechanism of alkaloids from Portulacae Herba on ulcerative colitis in mice based on TLR4/MyD88/NF-κB signaling pathway]., PMID:40350807
Nephropathy II Decoction Attenuates Renal Fibrosis via Regulating TLR4 and Gut Microbiota Along the Gut-Kidney Axis., PMID:40350306
Melatonin-mediated intestinal microbiota homeostasis improves skin barrier damage involvement of gut-skin axis dysfunction in aging mice., PMID:40349812
For research use only. Not for human or drug use.
