Catalog No.
YHJ47201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly2-Leu191
Predicted molecular weight
23.88 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99828
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CIBP, CIB1, Calcium- and integrin-binding protein, Calcium and integrin-binding protein 1, KIP, SIP2-28, DNA-PKcs-interacting protein, PRKDCIP, Calmyrin, CIB, Kinase-interacting protein, SNK-interacting protein 2-28
Constitutively active Arabidopsis cryptochrome 2 alleles identified using yeast selection and deep mutational scanning., PMID:40409553
Efficacy and safety of entrectinib in children with extracranial solid or central nervous system (CNS) tumours harbouring NTRK or ROS1 fusions., PMID:40086048
The Diverse Functions of the Calcium- and Integrin-Binding Protein Family., PMID:40076845
MmuPV1 infection of Tmc6/Ever1 or Tmc8/Ever2 deficient FVB mice as a model of βHPV in typical epidermodysplasia verruciformis., PMID:39813296
Light-dependent modulation of protein localization and function in living bacteria cells., PMID:39737933
Optogenetic control of receptor-mediated growth cone dynamics in neurons., PMID:39705378
Quantitative proteomics reveals extensive lysine ubiquitination and transcription factor stability states in Arabidopsis., PMID:39570863
Establishment of a CIB1 knockout human pluripotent stem cell line via CRISPR/Cas9 genome editing technology., PMID:39426048
High CIB1 expression in colorectal cancer liver metastases correlates with worse survival and the replacement histopathological growth pattern., PMID:39072289
Small-Molecule Disruptors of the Interaction between Calcium- and Integrin-Binding Protein 1 and Integrin αIIbβ3 as Novel Antiplatelet Agents., PMID:39022362
Deubiquitination of CIB1 by USP14 promotes lenvatinib resistance via the PAK1-ERK1/2 axis in hepatocellular carcinoma., PMID:38993552
In silico fragment-based discovery of CIB1-directed anti-tumor agents by FRASE-bot., PMID:38956119
Identification of unique cell type responses in pancreatic islets to stress., PMID:38956087
Deficiency in Ever2 does not increase susceptibility of mice to pathogenesis by the mouse papillomavirus, MmuPV1., PMID:38869286
Role of calcium integrin-binding protein 1 in the mechanobiology of the liver endothelium., PMID:38451745
Optogenetic induction of caspase-8 mediated apoptosis by employing Arabidopsis cryptochrome 2., PMID:38155283
Application of OpenArray Technology to Assess Changes in the Expression of Functionally Significant Genes in the Substantia Nigra of Mice in a Model of Parkinson's Disease., PMID:38137024
Monogenic etiologies of persistent human papillomavirus infections: A comprehensive systematic review., PMID:37978863
Cell Cycle Control by Optogenetically Regulated Cell Cycle Inhibitor Protein p21., PMID:37759593
Light-activated BioID - an optically activated proximity labeling system to study protein-protein interactions., PMID:37756605
Machine Learning-driven Fragment-based Discovery of CIB1-directed Anti-Tumor Agents by FRASE-bot., PMID:37645935
Identification of calcium and integrin-binding protein 1 as a reprogrammed glucose metabolism mediator to restrict immune cell infiltration in the stromal compartment of pancreatic ductal adenocarcinoma., PMID:37187730
CIB2 Is a Novel Endogenous Repressor of Atrial Remodeling., PMID:37128899
Exploration of the common genetic landscape of COVID-19 and male infertility., PMID:37020555
In silico Mutagenesis and Modeling of Decoy Peptides Targeting CIB1 to Obscure its Role in Triple-negative Breast Cancer Progression., PMID:36998135
Synthetic peptides for the precise transportation of proteins of interests to selectable subcellular areas., PMID:36890909
Whole transcriptome-based skin virome profiling in typical epidermodysplasia verruciformis reveals α-, β-, and γ-HPV infections., PMID:36602881
[Identification of novel regulators involved in AD pathogenesis using the CRISPR-Cas9 system]., PMID:36596482
Enzymatic Macrolactamization of mRNA Display Libraries for Inhibitor Selection., PMID:36490372
Cryo-EM structure of the CRY2 and CIB1 fragment complex provides insights into CIB1-mediated photosignaling., PMID:36371635
Optogenetic Methods to Control Tissue Mechanics in Drosophila., PMID:35980583
Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent Thrombus Formation under Shear., PMID:35955827
Strategies for Targeting CIB1: A Challenging Drug Target., PMID:35909278
Optogenetic Control of Membrane Trafficking Using Light-Activated Reversible Inhibition by Assembly Trap of Intracellular Membranes (IM-LARIAT)., PMID:35819773
Tumor-Infiltrated CD8+ T Cell 10-Gene Signature Related to Clear Cell Renal Cell Carcinoma Prognosis., PMID:35812454
Aldehyde Dehydrogenase 1B1 Is Implicated in DNA Damage Response in Human Colorectal Adenocarcinoma., PMID:35805102
Light-induced fermenter production of derivatives of the sweet protein monellin is maximized in prestationary Saccharomyces cerevisiae cultures., PMID:35481893
An optogenetic tool to recruit individual PKC isozymes to the cell surface and promote specific phosphorylation of membrane proteins., PMID:35367414
Calcium and integrin-binding protein 1-like interacting with an integrin α-cytoplasmic domain facilitates cellular immunity in Helicoverpa armigera., PMID:35231466
Case Report: Altered NK Cell Compartment and Reduced CXCR4 Chemotactic Response of B Lymphocytes in an Immunodeficient Patient With HPV-Related Disease., PMID:35154113
Cryptochrome 2 from Lilium × formolongi Regulates Photoperiodic Flowering in Transgenic Arabidopsis thaliana., PMID:34884732
CeLINC, a fluorescence-based protein-protein interaction assay in Caenorhabditis elegans., PMID:34849800
The Endoplasmic Reticulum Stress Sensor IRE1α Regulates the UV DNA Repair Response through the Control of Intracellular Calcium Homeostasis., PMID:34808241
Discovery and Development of Cyclic Peptide Inhibitors of CIB1., PMID:34795874
Expression of CIB1 correlates with colorectal liver metastases but not with peritoneal carcinomatosis., PMID:34794407
TMC8 mutation in a Turkish family with epidermodysplasia verruciformis including laryngeal papilloma and recurrent skin carcinoma., PMID:34416085
Calcium and integrin binding protein 1 (CIB1) induces myocardial fibrosis in myocardial infarction via regulating the PI3K/Akt pathway., PMID:34349085
Arabidopsis CIB3 regulates photoperiodic flowering in an FKF1-dependent way., PMID:33686404
Semi-In-Vivo Pull-Down Assay for Blue Light-Dependent Protein Interactions., PMID:33656680
Integrative public data-mining pipeline for the validation of novel independent prognostic biomarkers for lung adenocarcinoma., PMID:33336597