Catalog No.
YHJ46601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp1358-Phe1635
Predicted molecular weight
32.87 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99758
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ABCA3, ATP-binding cassette sub-family A member 3, Phospholipid-transporting ATPase ABCA3, ABC3, ATP-binding cassette 3, ATP-binding cassette transporter 3, ABC-C transporter, Xenobiotic-transporting ATPase ABCA3
Genetic Disorders of Surfactant Metabolism., PMID:40306683
The Role of Pulmonary Genetic Variations in the Pathogenesis of Pediatric Postinfectious Bronchiolitis Obliterans., PMID:40196942
Genome-wide identification of Tegillarca granosa ATP-binding cassette (ABC) transporter family related to arsenic toxicity., PMID:40015574
Alveolar epithelial paxillin in postnatal lung alveolar development., PMID:39991922
The molecular impact of miR-326 in acute lymphoblastic leukemia and its cross talk with P53., PMID:39909906
Neonatal meconium aspiration syndrome associated with ABCA3 gene mutation and mycoplasma infection: a case report., PMID:39789505
Neonatal respiratory distress syndrome in E292V homozygous ABCA3., PMID:39477456
ABCA3 c.838C>T (p.Arg280Cys, R280C) and c.697C>T (p.Gln233Ter, Q233X, Q233*) as Causative Variants for RDS: A Family Case Study and Literature Review., PMID:39457702
ABC transporters involved in respiratory and cholestatic diseases: From rare to very rare monogenic diseases., PMID:39111603
Cyclosporine A in children with ABCA3 deficiency., PMID:39041931
The formation of lamellar body-like structures may be a trigger of cetylpyridinium chloride-induced cell death and inflammatory response., PMID:38969275
Successful bilateral lung transplantation in a five-year-old child with pulmonary interstitial fibrosis caused by an ABCA3 gene mutation., PMID:38797337
High risk of lung cancer in surfactant-related gene variant carriers., PMID:38575158
ABCA3 mutation-induced congenital pulmonary surfactant deficiency: A case report., PMID:38552044
Evaluation of the Copy Number Variants and Single-Nucleotide Polymorphisms of ABCA3 in Newborns with Respiratory Distress Syndrome-A Pilot Study., PMID:38541145
Identification and prognostic analysis of candidate biomarkers for lung metastasis in colorectal cancer., PMID:38489730
Tumor-associated macrophage (TAM)-secreted CCL22 confers cisplatin resistance of esophageal squamous cell carcinoma (ESCC) cells via regulating the activity of diacylglycerol kinase α (DGKα)/NOX4 axis., PMID:38387281
Similarities and differences of interstitial lung disease associated with pathogenic variants in SFTPC and ABCA3 in adults., PMID:38345107
Genome-Wide Association Study of Milk Composition in Karachai Goats., PMID:38275787
SNARE-ing the Reason for Post-Cardiac Surgery Critical Illness-Related Corticosteroid Insufficiency., PMID:38275610
A Novel Mutation (Lys31Arg) in the DMD Gene Impacts on Neuromuscular Dysfunctions Found by Whole Exome Sequencing and In Silico Analyses in an Iranian Family., PMID:38265407
Human pluripotent stem cell modeling of alveolar type 2 cell dysfunction caused by ABCA3 mutations., PMID:38226623
LAMP3 is a potent uterine corpus endometrial carcinoma prognostic biomarker associated with immune behavior., PMID:38217544
Towards personalized therapies for genetic disorders of surfactant dysfunction., PMID:38036307
Increased Expression of the ABCA1 and ABCA3 Transporter Genes is Associated with Cisplatin Resistance in Breast Cancer Cells., PMID:38019257
Learning from cystic fibrosis: How can we start to personalise treatment of Children's Interstitial Lung Disease (chILD)?, PMID:37996258
Characterization of the congenital diaphragmatic hernia model in C57BL/6J fetal mice: a step toward lineage tracing experiments., PMID:37981587
GCN5L1 regulates pulmonary surfactant production by modulating lamellar body biogenesis and trafficking in mouse alveolar epithelial cells., PMID:37936104
ABCA3 and LZTFL1 Polymorphisms and Risk of COVID-19 in the Czech Population., PMID:37795896
Genetics of bronchopulmonary dysplasia: An update., PMID:37775368
Interstitial lung disease in a family with bi-allelic variants in ABCA3: non-specific interstitial pneumonitis pattern of injury., PMID:37657992
The clinical importance of pulmonary gene and protein expression levels in an infant with lethal ABCA3 variants., PMID:37477506
ABCA3 Deficiency-Variant-Specific Response to Hydroxychloroquine., PMID:37175887
Quantifying Functional Impairment of ABCA3 Variants Associated with Interstitial Lung Disease., PMID:37108718
Use of Berlin EXCOR cannulas in both venovenous and venoarterial central extracorporeal membrane oxygenation configurations overcomes the problem of cannula instability while bridging infants and young children to lung transplant., PMID:37096088
Identification and characterization of ABC proteins in an important rice insect pest, Cnaphalocrocis medinalis unveil their response to Cry1C toxin., PMID:36894061
ATP binding cassette member A3 (ABCA3): coming of age., PMID:36863776
ABCA3-related interstitial lung disease beyond infancy., PMID:36808083
Deciphering an isolated lung phenotype of NKX2-1 frameshift pathogenic variant., PMID:36733766
[Interstitial lung diseases in children of genetic origin]., PMID:36564324
The Genetic and Epigenetic Footprint in Idiopathic Pulmonary Fibrosis and Familial Pulmonary Fibrosis: A State-of-the-Art Review., PMID:36553114
Novel insights into congenital surfactant dysfunction disorders by in silico analysis of ABCA3 proteins., PMID:36404394
Living Donor Lobar Lung Transplant for a Patient With Lung Disease Caused by ABCA3 Gene Mutations: A Case Report., PMID:36376106
Inherited pulmonary surfactant metabolism disorders in Argentina: Differences between patients with SFTPC and ABCA3 variants., PMID:36324278
Cell density modulates chemoresistance in breast cancer cells through differential expression of ABC transporters., PMID:36319789
Instability of Mature ABCA3 Protein: Toward a New Classification of ABCA3 Mutations?, PMID:36318016
Gene Therapeutics for Surfactant Dysfunction Disorders: Targeting the Alveolar Type 2 Epithelial Cell., PMID:36166236
Variable Expression of Lung Disease Due to a Novel Homozygous ABCA3 Variant., PMID:36121785
The clinical course of interstitial lung disease in an adult patient with an ABCA3 homozygous complex allele under hydroxychloroquine and a review of the literature., PMID:36118545
Cigarette smoke extract combined with LPS reduces ABCA3 expression in chronic pulmonary inflammation may be related to PPARγ/ P38 MAPK signaling pathway., PMID:36115154
For research use only. Not for human or drug use.
