Catalog No.
YHJ44201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Trp50-Asp320
Predicted molecular weight
56.57 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99523
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Neurotensin receptor 3, Gp95, Glycoprotein 95, Sortilin, 100 kDa NT receptor, NTR3, SORT1, NT3
Predictive value of serum sortilin, HMGB1, and galanin-like peptide for gestational diabetes mellitus in women with polycystic ovary syndrome., PMID:40458174
BDNF/proBDNF Interplay in the Mediation of Neuronal Apoptotic Mechanisms in Neurodegenerative Diseases., PMID:40430064
The antioxidant stress effect of granulin precursor in vitiligo., PMID:40415096
Acid sphingomyelinase recruits palmitoylated CD36 to membrane rafts and enhances lipid uptake., PMID:40348192
Function and application of brain‑derived neurotrophic factor precursors (Review)., PMID:40341415
Soluble SorLA in CSF, a novel biomarker to explore disrupted trafficking of SorLA protein in Alzheimer disease., PMID:40336092
Sortilin-Mediated Rapid, Precise and Sustained Degradation of Membrane Proteins via mRNA-Encoded Lysosome-Targeting Chimera., PMID:40305781
PAI-1 interaction with sortilin-related receptor 1 is required for lung fibrosis., PMID:40299646
Effect of metformin on the endometrial proteome of diet-induced obese mice., PMID:40214723
Dysregulation of proBDNF/p75NTR and BDNF/TrkB Signaling in Acute Ischemic Stroke: Different Sides of the Same Coins., PMID:40209946
The Alzheimer's Disease Gene SORL1 Regulates Lysosome Function in Human Microglia., PMID:40183375
Tea Polysaccharide Ameliorates Atherosclerosis by Inhibiting Insulin Resistance-Mediated Hepatic VLDL Overproduction., PMID:40173269
Saffron and its active constituents ameliorate hypercholesterolemia by inhibiting PCSK9 and modulating Sortilin, LDLR, and SREBP-2 signaling in high fat diet induced hypercholesterolemic C57BL/6 mice., PMID:40157403
Evaluating maternal serum sortilin levels: a potential biomarker for predicting preeclampsia., PMID:40133840
Serum sortilin-derived propeptide concentrations as markers of depression in chronic stroke., PMID:40107034
Self-assembly of the insulin-responsive vesicles creates a signaling platform for the insulin action on glucose uptake., PMID:40097254
Mechanism of Wuling powder modulating proBDNF/p75NTR/sortilin and BDNF/TrkB pathways in the treatment of ulcerative colitis complicated with depression., PMID:40062332
Neurotensin Regulates Primate Ovulation Via Multiple Neurotensin Receptors., PMID:40037635
EHBP1 suppresses liver fibrosis in metabolic dysfunction-associated steatohepatitis., PMID:40015280
Sortilin and L-type Calcium Channels May be Involved in the Unusual Mechanism of proBDNF Signaling in Regenerating Mouse Neuromuscular Junctions., PMID:39998597
Serum Sortilin Levels as a Biomarker for Metabolic and Hormonal Dysregulation in Polycystic Ovary Syndrome., PMID:39997347
Astragalus polysaccharide attenuates retinal ischemia reperfusion-induced microglial activation through sortilin-related vacuolar protein sorting 10 domain containing receptor 2/laminin subunit alpha 1 upregulation., PMID:39958884
FOXP1 is a Transcription Factor for the Alzheimer's Disease Risk Gene SORL1., PMID:39902677
Extracellular Vesicles and Tunnelling Nanotubes as Mediators of Prostate Cancer Intercellular Communication., PMID:39858418
RPS23RG1 inhibits SORT1-mediated lysosomal degradation of MDGA2 to protect against autism., PMID:39816685
Hsa_circ_0109623 regulates the progression of autoimmune liver disease through Hsa_miR_146b-3p/Sortilin 1-mediated activation of CD4+ T cells., PMID:39774281
miR-432-5p Targeting SORT1 to Protect Artery Smooth Muscle Cells and Inhibit Coronary Artery Disease., PMID:39730974
Systemic mechanism of Panax noteginseng saponins in antiaging based on network pharmacology combined with experimental validation., PMID:39691419
Alzheimer's Disease Risk Gene SORL1 Promotes Receptiveness of Human Microglia to Pro-Inflammatory Stimuli., PMID:39688327
Impaired chaperone-mediated autophagy leads to abnormal SORT1 (sortilin 1) turnover and CES1-dependent triglyceride hydrolysis., PMID:39611307
Haploinsufficiency and Alzheimer's Disease: The Possible Pathogenic and Protective Genetic Factors., PMID:39596030
Phosphorylation on serine 72 modulates Rab7A palmitoylation and retromer recruitment., PMID:39584231
Contribution of amyloid deposition from oligodendrocytes in a mouse model of Alzheimer's disease., PMID:39548583
Neurotensin and Its Involvement in Female Hormone-Sensitive Cancers., PMID:39519199
Evaluating SORT1 and SESN1 genes expression in peripheral blood mononuclear cells and oxidative stress status in patients with coronary artery disease., PMID:39488678
Increased expression of the proapoptotic presenilin associated protein is involved in neuronal tangle formation in human brain., PMID:39455681
Ex vivo nanoscale abluminal mapping of putative cargo receptors at the blood-brain barrier of expanded brain capillaries., PMID:39402596
New Marker in the Umbilical Cord Blood of Fetuses with Fetal Growth Restriction: Serum Sortilin-1 Level., PMID:39387812
Diagnostic utility of sortilin & other biomarkers in the diagnosis of carotid & coronary atherosclerosis in individuals with arterial hypertension., PMID:39382416
Carboxy-terminal blockade of sortilin binding enhances progranulin gene therapy, a potential treatment for frontotemporal dementia., PMID:39345608
Designed endocytosis-inducing proteins degrade targets and amplify signals., PMID:39322662
6-methylcoumarin/miR-122 suppresses hepatic Sortilin-mediated ApoB-100 secretion to attenuate aortic atherosclerosis., PMID:39243919
Sortilin-mediated translocation of mitochondrial ACSL1 impairs adipocyte thermogenesis and energy expenditure in male mice., PMID:39232011
Endo-Lysosomal Network Disorder Reprograms Energy Metabolism in SorL1-Null Rat Hippocampus., PMID:39225620
Sortilin is associated with progranulin deficiency and autism-like behaviors in valproic acid-induced autism rats., PMID:39218796
Genetic structure analysis of yak breeds and their response to adaptive evolution., PMID:39218165
PAI-1 Interaction with Sortilin Related Receptor-1 is Required for Lung Fibrosis., PMID:39211273
Effect of Sortilin1 on promoting angiogenesis and systemic metastasis in hepatocellular carcinoma via the Notch signaling pathway and CD133., PMID:39209807
An anti-sortilin affibody-peptide fusion inhibits sortilin-mediated progranulin degradation., PMID:39185427
Sortilin is dispensable for secondary injury processes following traumatic brain injury in mice., PMID:39170542
For research use only. Not for human or drug use.
