Catalog No.
YHJ43901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg117-Val199
Predicted molecular weight
11.80 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99489
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DDO, D-aspartate oxidase, DASOX
Structural Optimization of Pyrazole Compounds as Hsp90 Regulators with Enhanced Antitumor Activity., PMID:40310691
Inhibition of Alkbh5 Attenuates Lipopolysaccharide-Induced Lung Injury by Promoting Ccl1 m6A and Treg Recruitment., PMID:40254698
An Exploratory Genomic and Transcriptomic Analysis Between Choloepus didactylus and Homo sapiens., PMID:40149424
Multi-Water Bridges Enable Design of BET BD1-Selective Inhibitors for Pancreatic Cancer Therapy., PMID:40011026
Discovery of the salicylaldehyde-based compound DDO-02267 as a lysine-targeting covalent inhibitor of ALKBH5., PMID:39740322
Nuclear Factor Erythroid 2-Related Factor 2 Activator DDO-1039 Ameliorates Podocyte Injury in Diabetic Kidney Disease via Suppressing Oxidative Stress, Inflammation, and Ferroptosis., PMID:39723566
DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge., PMID:39692514
Allosteric CDC37 Inhibitor Disrupts Chaperone Complex to Block CDK4/6 Maturation., PMID:39582167
DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge., PMID:39553933
Allosteric Activation of Protein Phosphatase 5 with Small Molecules., PMID:39145509
Li-Fraumeni Syndrome: Imaging Features and Guidelines., PMID:39024172
Apolipoprotein B: Bridging the Gap Between Evidence and Clinical Practice., PMID:38950110
Comprehensive analysis of two hotspot codons in the TUBB4B gene and associated phenotypes., PMID:38719929
Systemic delivery of mutant huntingtin lowering antisense oligonucleotides to the brain using apolipoprotein A-I nanodisks for Huntington disease., PMID:38215984
Rational design of peptide inhibitors targeting HSP90-CDC37 protein-protein interaction., PMID:38189168
Screening of Crucial Cytosolicproteins Interconnecting the Endoplasmic Reticulum and Mitochondria in Parkinson's Disease and the Impact of Anti-Parkinson Drugs in the Preservation of Organelle Connectivity., PMID:38002511
Discovery of Pyrazolo[1,5-a]pyrimidine Derivative as a Novel and Selective ALKBH5 Inhibitor for the Treatment of AML., PMID:37983486
Improvement of Learning and Memory by Elevating Brain D-Aspartate in a Mouse Model of Fragile X Syndrome., PMID:37453994
Discovery of 1H-Imidazo[4,5-b]pyridine Derivatives as Potent and Selective BET Inhibitors for the Management of Neuropathic Pain., PMID:37382379
Novel Hydrogen Sulfide Hybrid Derivatives of Keap1-Nrf2 Protein-Protein Interaction Inhibitor Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis., PMID:37237928
The impact of RNA binding proteins and the associated long non-coding RNAs in the TCA cycle on cancer pathogenesis., PMID:37221841
D-Aspartate Depletion Perturbs Steroidogenesis and Spermatogenesis in Mice., PMID:37189369
Endothelial Damage Arising From High Salt Hypertension Is Elucidated by Vascular Bed Systematic Profiling., PMID:36700429
Non-standard viral genome-derived RNA activates TLR3 and type I IFN signaling to induce cDC1-dependent CD8+ T-cell responses during vaccination in mice., PMID:36333225
Inflammation and apoptosis pathways mediated the stress response of Litopenaeus vannamei to acute cold and air exposure during waterless live transportation: Based on ultrastructure and transcriptome., PMID:36252695
D-aspartate oxidase gene duplication induces social recognition memory deficit in mice and intellectual disabilities in humans., PMID:35915065
Epigenome-wide DNA methylation study of whole blood in patients with sporadic amyotrophic lateral sclerosis., PMID:35853630
Target Fishing Reveals a Novel Mechanism of 1,2,4-Oxadiazole Derivatives Targeting Rpn6, a Subunit of 26S Proteasome., PMID:35253427
Design, synthesis, and biological evaluation of arylmethylpiperidines as Kv1.5 potassium channel inhibitors., PMID:35012386
Glyoxylate reductase/hydroxypyruvate reductase regulates the free d-aspartate level in mammalian cells., PMID:34289161
Discovery of a potent MLL1 and WDR5 protein-protein interaction inhibitor with in vivo antitumor activity., PMID:34225179
Discovery of DDO-2213 as a Potent and Orally Bioavailable Inhibitor of the WDR5-Mixed Lineage Leukemia 1 Protein-Protein Interaction for the Treatment of MLL Fusion Leukemia., PMID:34105966
Proteomic analysis of liver tissues in chicken embryo at Day 16 and Day 20 reveals antioxidant mechanisms., PMID:33962068
Molecular and morphological findings in a sample of oral surgery patients: What can we learn for multivariate concepts for age estimation?, PMID:33942892
Discovery of a covalent inhibitor of heat shock protein 90 with antitumor activity that blocks the co-chaperone binding via C-terminal modification., PMID:33932325
Cellular studies of the two main isoforms of human d-aspartate oxidase., PMID:33650155
Prenatal and Early Postnatal Cerebral d-Aspartate Depletion Influences l-Amino Acid Pathways, Bioenergetic processes, and Developmental Brain Metabolism., PMID:33274941
Analysis of nonideality: insights from high concentration simulations of sedimentation velocity data., PMID:33159218
Design, synthesis and bioevaluation of inhibitors targeting HSP90-CDC37 protein-protein interaction based on a hydrophobic core., PMID:33109397
Modeling DNA Methylation Profiles through a Dynamic Equilibrium between Methylation and Demethylation., PMID:32899254
New insights on the influence of free d-aspartate metabolism in the mammalian brain during prenatal and postnatal life., PMID:32561430
Deep learning-enabled point-of-care sensing using multiplexed paper-based sensors., PMID:32411827
Biochemical characterization of d-aspartate oxidase from Caenorhabditis elegans: its potential use in the determination of free d-glutamate in biological samples., PMID:32376478
D-Aspartate oxidase: distribution, functions, properties, and biotechnological applications., PMID:32043187
Discovery and Optimization of Small Molecules Targeting the Protein-Protein Interaction of Heat Shock Protein 90 (Hsp90) and Cell Division Cycle 37 as Orally Active Inhibitors for the Treatment of Colorectal Cancer., PMID:31935086
Structure and kinetic properties of human d-aspartate oxidase, the enzyme-controlling d-aspartate levels in brain., PMID:31914658
A single combination gene therapy treats multiple age-related diseases., PMID:31685628
Selective demethylation of two CpG sites causes postnatal activation of the Dao gene and consequent removal of D-serine within the mouse cerebellum., PMID:31661019
Restoration of visual function by transplantation of optogenetically engineered photoreceptors., PMID:31586094
Small-molecule inhibitor targeting the Hsp90-Cdc37 protein-protein interaction in colorectal cancer., PMID:31555737
For research use only. Not for human or drug use.
