Catalog No.
YHJ43601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr430-Gly626
Predicted molecular weight
24.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99467
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Radioprotective 105 kDa protein, Lymphocyte antigen 64, RP105, LY64, CD180 antigen, CD180
Integrative immunology identified interferome signatures in uveitis and systemic disease-associated uveitis., PMID:40270958
Disturbed Complement Receptor Expression Pattern of B Cells Is Enhanced by Toll-like Receptor CD180 Ligation in Diffuse Cutaneous Systemic Sclerosis., PMID:39273179
Toll-like Receptor Homologue CD180 Ligation of B Cells Upregulates Type I IFN Signature in Diffuse Cutaneous Systemic Sclerosis., PMID:39063175
MD-1 downregulation is associated with reduced cell surface CD180 expression in CLL., PMID:38897026
Empirical Study on Exploring the Role of CD180 and MD-1 Prognostic Indicators for the Chronic Lymphocytic Leukaemia (CLL) Disease., PMID:37902045
Mucosal expression of PI3, ANXA1, and VDR discriminates Crohn's disease from ulcerative colitis., PMID:37891214
Irradiation Attenuates Systemic Lupus Erythematosus-Like Morbidity in NZBWF1 Mice: Focusing on CD180-Negative Cells., PMID:37886369
The role of CD180 in hematological malignancies and inflammatory disorders., PMID:37460961
Identification of a three-gene prognostic signature for radioresistant esophageal squamous cell carcinoma., PMID:36699628
Distinct contributions of the innate immune receptors TLR2 and RP105 to formation and architecture of structured lung granulomas in mice infected with Mycobacterium tuberculosis., PMID:36370035
Identification of Immune Infiltration and Effective Immune Biomarkers in Acute Lung Injury by Bioinformatics Analysis., PMID:36165281
Age-related decline in the resistance of mice to bacterial infection and in LPS/TLR4 pathway-dependent neutrophil responses., PMID:36090969
Proteomic and phosphoproteomic landscapes of acute myeloid leukemia., PMID:35895896
Screening of Diabetic Nephropathy Progression-Related Genes Based on Weighted Gene Co-expression Network Analysis., PMID:35834115
Ligation of TLR Homologue CD180 of B Cells Activates the PI3K/Akt/mTOR Pathway in Systemic Sclerosis and Induces a Pathological Shift in the Expression of BAFF Receptors., PMID:35743222
SLAMF8 Participates in Acute Renal Transplant Rejection via TLR4 Pathway on Pro-Inflammatory Macrophages., PMID:35432371
High-Dimensional Analysis Reveals Distinct Endotypes in Patients With Idiopathic Inflammatory Myopathies., PMID:35371068
Low NCOR2 levels in multiple myeloma patients drive multidrug resistance via MYC upregulation., PMID:34864816
The Potential Role of RP105 in Regulation of Inflammation and Osteoclastogenesis During Inflammatory Diseases., PMID:34414191
Galectin-9 regulates the threshold of B cell activation and autoimmunity., PMID:34369876
Expression patterns of CD180 in the lymph nodes of patients with chronic lymphocytic leukaemia., PMID:34227107
Toll-Like Receptor Homolog CD180 Expression Is Diminished on Natural Autoantibody-Producing B Cells of Patients with Autoimmune CNS Disorders., PMID:34124274
A new score including CD43 and CD180: Increased diagnostic value for atypical chronic lymphocytic leukemia., PMID:34061467
CD150 and CD180 are negative regulators of IL-10 expression and secretion in chronic lymphocytic leukemia B cells., PMID:33904315
Analysis of PI3K Pathway Associated Molecules Reveals Dysregulated Innate and Adaptive Functions of B Cells in Early Diffuse Cutaneous Systemic Sclerosis., PMID:33809015
The relative expression levels of CD148 and CD180 on clonal B cells and CD148/CD180 median fluorescence intensity ratios are useful in the characterization of mature B cell lymphoid neoplasms infiltrating blood and bone marrow - Results from a single centre pilot study., PMID:33455071
A Novel Gene Delivery Vector of Agonistic Anti-Radioprotective 105 Expressed on Cell Membranes Shows Adjuvant Effect for DNA Immunization Against Influenza., PMID:33414788
B cell targeting by molecular adjuvants for enhanced immunogenicity., PMID:33252273
Piperine protects against pyroptosis in myocardial ischaemia/reperfusion injury by regulating the miR-383/RP105/AKT signalling pathway., PMID:33219747
Clinical trait-connected network analysis reveals transcriptional markers of active psoriasis treatment with Liangxue-Jiedu decoction., PMID:33152434
Transcriptome Analysis Identifies Novel Prognostic Genes in Osteosarcoma., PMID:33082842
[Toll-like receptor CD180 and the bone marrow microenvironment as therapeutic targets in multiple myeloma]., PMID:32759572
RP105 plays a cardioprotective role in myocardial ischemia reperfusion injury by regulating the Toll‑like receptor 2/4 signaling pathways., PMID:32626996
Sensitivity of chronic lymphocytic leukemia cells to chemotherapeutic drugs ex vivo depends on expression status of cell surface receptors., PMID:32231196
Toll-Like Receptor Mediated Activation of Natural Autoantibody Producing B Cell Subpopulations in an Autoimmune Disease Model., PMID:31817576
Inhibition of microRNA-141-3p Reduces Hypoxia-Induced Apoptosis in H9c2 Rat Cardiomyocytes by Activating the RP105-Dependent PI3K/AKT Signaling Pathway., PMID:31532760
Targeting Antigens to CD180 but Not CD40 Programs Immature and Mature B Cell Subsets to Become Efficient APCs., PMID:31484732
Ligation of CD180 contributes to endotoxic shock by regulating the accumulation and immunosuppressive activity of myeloid-derived suppressor cells through STAT3., PMID:30557700
[Characteristics of CD180 Expression and Its Diagnostic Value in B Cell Chronic Lymphoproliferative Disorders]., PMID:30501725
CD180 Ligation Inhibits TLR7- and TLR9-Mediated Activation of Macrophages and Dendritic Cells Through the Lyn-SHP-1/2 Axis in Murine Lupus., PMID:30498494
Transcriptome Analysis Provides Insights into the Markers of Resting and LPS-Activated Macrophages in Grass Carp (Ctenopharyngodon idella)., PMID:30424518
Down-Regulation of miR-327 Alleviates Ischemia/Reperfusion-Induced Myocardial Damage by Targeting RP105., PMID:30196287
[Involvement of innate immunity in the expansion of multiple myeloma cells and therapeutic intervention with lenalidomide]., PMID:30185705
Canine leishmaniasis: Genome-wide analysis and antibody response to Lutzomyia longipalpis saliva., PMID:29742167
RP105 ameliorates hypoxia̸reoxygenation injury in cardiac microvascular endothelial cells by suppressing TLR4̸MAPKs̸NF-κB signaling., PMID:29693119
A low dose lipid infusion is sufficient to induce insulin resistance and a pro-inflammatory response in human subjects., PMID:29649324
RP105 alleviates myocardial ischemia reperfusion injury via inhibiting TLR4/TRIF signaling pathways., PMID:29512709
A multi-omic analysis reveals the regulatory role of CD180 during the response of macrophages to Borrelia burgdorferi., PMID:29511161
RP105 protects PC12 cells from oxygen‑glucose deprivation/reoxygenation injury via activation of the PI3K/AKT signaling pathway., PMID:29436577
Myeloma Cells Are Activated in Bone Marrow Microenvironment by the CD180/MD-1 Complex, Which Senses Lipopolysaccharide., PMID:29363546
For research use only. Not for human or drug use.
