Catalog No.
YHJ43401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Tyr269
Predicted molecular weight
31.80 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99439
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Calponin H2, smooth muscle, Calponin-2, CNN2, Neutral calponin
Exploring potential diagnostic markers and therapeutic targets for type 2 diabetes mellitus with major depressive disorder through bioinformatics and in vivo experiments., PMID:40369032
Quantitative serum proteomic analysis for biomarker discovery in post-COVID-19 postural orthostatic tachycardia syndrome (PC-POTS) patients., PMID:40022872
Serum proteomic and metabolomic profiling of hepatocellular carcinoma patients co-infected with Clonorchis sinensis., PMID:39840062
Loss of Calponin 2 causes premature ovarian insufficiency in mice., PMID:38336796
Cuproptosis/OXPHOS tendency prediction of prognosis and immune microenvironment of esophageal squamous cell carcinoma: Bioinformatics analysis and experimental validation., PMID:38211899
Differential regulation of hair cell actin cytoskeleton mediated by SRF and MRTFB., PMID:37982489
The CRL3gigaxonin ubiquitin ligase-USP15 pathway governs the destruction of neurofilament proteins., PMID:37903270
Calponin 2 regulates ketogenesis to mitigate acute kidney injury., PMID:37751293
The Role of H2-Calponin Antigen in Cancer Metastasis: Presence of Autoantibodies in Liver Cancer Patients., PMID:37373013
CNN2 silencing inhibits colorectal cancer development through promoting ubiquitination of EGR1., PMID:37188478
Calponin 2 harnesses metabolic reprogramming to determine kidney fibrosis., PMID:36963615
Scalable Generation of Nanovesicles from Human-Induced Pluripotent Stem Cells for Cardiac Repair., PMID:36430812
Identification of an 11 immune-related gene signature as the novel biomarker for acute myocardial infarction diagnosis., PMID:36182975
Loss of Calponin 2 causes age-progressive proteinuria in mice., PMID:36117313
circCNN2 Accelerates Cell Proliferation and Invasion in Lung Squamous Cell Carcinoma via Regulating miR-184/E2F1 and Activating MAPK Signaling Pathway., PMID:36016851
Exome Sequencing Reveals Genetic Variability and Identifies Chronic Prognostic Loci in Chinese Sarcoidosis Patients., PMID:35860586
Ubiquitin profiling of lysophagy identifies actin stabilizer CNN2 as a target of VCP/p97 and uncovers a link to HSPB1., PMID:35793674
Serum calponin 2 is a novel biomarker of tubal ectopic pregnancy., PMID:34217487
A rapid degradation of calponin 2 is required for cytokinesis., PMID:34133238
Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer's disease., PMID:33729626
Deletion of Calponin 2 Reduces the Formation of Postoperative Peritoneal Adhesions., PMID:33622156
Normalization Method Utilizing Endogenous Proteins for Quantitative Proteomics., PMID:32268065
Ectopic expression of CNN2 of colon cancer promotes cell migration., PMID:35117451
Identification of Proteins Differentially Expressed by Adipose-derived Mesenchymal Stem Cells Isolated from Immunodeficient Mice., PMID:31151297
Double deletion of calponin 1 and calponin 2 in mice decreases systemic blood pressure with blunted length-tension response of aortic smooth muscle., PMID:30707993
Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Aβ and TAU proteostasis., PMID:30371777
Deletion of calponin 2 attenuates the development of calcific aortic valve disease in ApoE-/- mice., PMID:30053524
Lentivirus-mediated shRNA Targeting CNN2 Inhibits Hepatocarcinoma in Vitro and in Vivo., PMID:29333089
OLR1 scavenger receptor knockdown affects mitotic gene expression but is dispensable for oxidized phospholipid- mediated stress signaling in SZ 95 sebocytes., PMID:29103984
Overall survival in EGFR mutated non-small-cell lung cancer patients treated with afatinib after EGFR TKI and resistant mechanisms upon disease progression., PMID:28854272
Knockdown of calponin 2 suppressed cell growth in gastric cancer cells., PMID:28714360
Deletion of Calponin 2 in Mouse Fibroblasts Increases Myosin II-Dependent Cell Traction Force., PMID:27733037
Deletion of calponin 2 in macrophages alters cytoskeleton-based functions and attenuates the development of atherosclerosis., PMID:27575021
Deletion of calponin 2 in macrophages attenuates the severity of inflammatory arthritis in mice., PMID:27488671
Calponin isoforms CNN1, CNN2 and CNN3: Regulators for actin cytoskeleton functions in smooth muscle and non-muscle cells., PMID:26970176
The potential role of DNA methylation in abdominal aortic aneurysms., PMID:25993294
Mechanoregulation of h2-calponin gene expression and the role of Notch signaling., PMID:24285540
Androgen-responsive serum response factor target genes regulate prostate cancer cell migration., PMID:23576568
Calponin 2 acts as an effector of noncanonical Wnt-mediated cell polarization during neural crest cell migration., PMID:23499442
Increased fibroblast functionality on CNN2-loaded titania nanotubes., PMID:22403489
Analysis of differentially expressed genes in human rectal carcinoma using suppression subtractive hybridization., PMID:21331762
CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response., PMID:20368616
Role of H2-calponin in regulating macrophage motility and phagocytosis., PMID:18617524
Identification of dysregulated genes in cutaneous squamous cell carcinoma., PMID:16865251
A critical role for calponin 2 in vascular development., PMID:16317011
Coordinate gene expression patterns during osteoblast maturation and retinoic acid treatment of MC3T3-E1 cells., PMID:12203032
For research use only. Not for human or drug use.
