Catalog No.
YHJ43101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu224
Predicted molecular weight
27.48 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99259
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Glutamate decarboxylase 1, GAD1, GAD-67, Glutamate decarboxylase 67 kDa isoform, GAD67, GAD, 67 kDa glutamic acid decarboxylase
Metabolome and transcriptome analyses reveal the mechanism underlying the differences in skin development between the two duck breeds during embryonic stage., PMID:40499236
Intracellular accumulation of amyloid-ß is a marker of selective neuronal vulnerability in Alzheimer's disease., PMID:40467545
A comprehensive spatiotemporal map of dystrophin isoform expression in the developing and adult human brain., PMID:40400011
Anlotinib mediates intrinsic drug resistance in hepatoblastoma through the GAD1/GABA pathway., PMID:40369243
Activation of CaMKII+ neurons in the paramedian raphe nucleus promotes general anesthesia in male mice., PMID:40360778
Excitation-inhibition imbalance in the auditory cortex causes sound recognition impairment in noisy environment in hidden hearing loss mice., PMID:40334993
Prenatal exposure to Bisphenol A sex-specifically disrupts prepulse inhibition and decreases parvalbumin-positive neurons in the prefrontal cortex of adult rats., PMID:40311724
Anodal direct current stimulation of the auditory cortex at the onset of presbycusis delays cortical aging., PMID:40278941
Characterizing the phenotype of pre-Bötzinger Complex neurons in rats., PMID:40252719
Prenatal Exposure To Valproic Acid Induces Increased Autism-Like Behaviors and Impairment of Learning and Memory Functions in Rat Offspring by Upregulating ADAM10 Expression., PMID:40240730
Bexarotene Promotes Neuroblastoma SH-SY5Y Cell Differentiation to Mature Neurons with Decreased Proliferation., PMID:40229457
Pterostilben upregulates GAD67-mediated GABA synthesis in hippocampal parvalbumin-positive cells., PMID:40189131
Candidate Key Proteins in Tinnitus-A Bioinformatic Study of Synaptic Transmission in the Inferior Colliculus., PMID:40076458
Ventromedial hypothalamic nucleus neuronal nitric oxide knockdown effects on GABAergic neuron metabolic sensor and transmitter marker gene expression in the male rat., PMID:39994513
Quantifying multilabeled brain cells in the whole prefrontal cortex reveals reduced inhibitory and a subtype of excitatory neuronal marker expression in serotonin transporter knockout rats., PMID:39932853
CRISPR-based epigenetic editing of Gad1 improves synaptic inhibition and cognitive behavior in a Tauopathy mouse model., PMID:39894446
AsGAD1 cloned from creeping bentgrass modulates cadmium tolerance of Arabidopsis thaliana by remodelling membrane lipids and cadmium uptake, transport and chelation., PMID:39868657
Action inflexibility and compulsive-like behavior accompany neurobiological alterations in the anterior orbitofrontal cortex and associated striatal nuclei., PMID:39805892
Hippocampal reelin and GAD67 gene expression and methylation in the GFAP.HMOX1 mouse model of schizophrenia., PMID:39798610
Human Leukocyte Antigen Polymorphism and Blood Biomarker Profiles in Parkinson's Disease: A Pilot Study in a Latvian Cohort., PMID:39767615
GABA/Glutamate Neuron Differentiation Imbalance and Increased AKT/mTOR Signaling in CNTNAP2-/- Cerebral Organoids., PMID:39758604
The de novo synthesis of GABA and its gene regulatory function control hepatocellular carcinoma metastasis., PMID:39740661
Whole-Genome Sequence Analysis of Flammulina filiformis and Functional Validation of Gad, a Key Gene for γ-Aminobutyric Acid Synthesis., PMID:39728358
Ketamine impairs the performance of male mice in novel recognition object test and reduces the immunoreactivity of GAD67 in the hippocampus: Role of pioglitazone., PMID:39725040
Identification of early Alzheimer's disease subclass and signature genes based on PANoptosis genes., PMID:39650656
Alterations in hippocampal somatostatin interneurons, GABAergic metabolism, and ASL perfusion in an aged male mouse model of POCD aggravated by sleep fragmentation., PMID:39648073
Optogenetic stimulation of the "Zusanli" acupoint alleviates inflammatory pain through active Wnt/β-Catenin and MAPK signaling pathway in rats., PMID:39553603
GABAergic circuit interaction between central amygdala and bed nucleus of the stria terminalis in lipopolysaccharide-induced despair-like behavior., PMID:39551417
Effects of Acute Haloperidol Treatment on Dopaminergic Markers, GAD67, and A2A Receptors in Rats with High and Low VCMs., PMID:39540951
Dorsomedial Ventromedial Hypothalamic Nucleus Growth Hormone-Releasing Hormone Neuron Steroidogenic Factor-1 Gene Targets in Female Rat., PMID:39401164
Senegenin regulates the mechanism of insomnia through the Keap1/Nrf2/PINK1/Parkin pathway mediated by GAD67., PMID:39380353
Heterologous expression and purification of glutamate decarboxylase-1 from the model plant Arabidopsis thaliana: Characterization of the enzyme's in vitro truncation by thiol endopeptidase activity., PMID:39343154
Vasopressin regulates social play behavior in sex-specific ways through glutamate modulation in the lateral septum., PMID:39304743
GAD65 tunes the functions of Best1 as a GABA receptor and a neurotransmitter conducting channel., PMID:39277606
GAD1 ameliorates glioma progression through regulating cuproptosis via RAS/MAPK pathway., PMID:39264832
DNA methylation and histone modifications associated with antipsychotic treatment: a systematic review., PMID:39227433
Identification of the Shared Gene Signatures Between Alzheimer's Disease and Diabetes-Associated Cognitive Dysfunction by Bioinformatics Analysis Combined with Biological Experiment., PMID:39213070
Common molecular and pathophysiological underpinnings of delirium and Alzheimer's disease: molecular signatures and therapeutic indications., PMID:39210294
Embryonic exposure to environmental factors drives transmitter switching in the neonatal mouse cortex causing autistic-like adult behavior., PMID:39178233
Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes., PMID:39163201
Effects of gestational hypothyroidism on mouse brain development: Gabaergic systems and oxidative stress., PMID:39048051
Posttraumatic epilepsy: Integrating clinical, inflammatory, and genetic profiles in traumatic brain injury patients., PMID:39024832
Steroidogenic Factor-1 Regulation of Dorsomedial Ventromedial Hypothalamic Nucleus Ghrh Neuron Transmitter Marker and Estrogen Receptor Gene Expression in Male Rat., PMID:39024550
Schizophrenia-Like Deficits and Impaired Glutamate/Gamma-aminobutyric acid Homeostasis in Zfp804a Conditional Knockout Mice., PMID:38988003
Novel Therapies for ANCA-associated Vasculitis: Apilimod Ameliorated Endothelial Cells Injury through TLR4/NF-κB Pathway and NLRP3 Inflammasome., PMID:38910483
Glucose transporter-2 regulation of VMN GABA neuron metabolic sensor and transmitter gene expression., PMID:38902332
Inhibitory Subpopulations in preBötzinger Complex Play Distinct Roles in Modulating Inspiratory Rhythm and Pattern., PMID:38729762
GABA transporter mGat4 is involved in multiple neural functions in mice., PMID:38697303
Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia., PMID:38684795
GABA does not regulate stomatal CO2 signalling in Arabidopsis., PMID:38628155
For research use only. Not for human or drug use.
