Catalog No.
                        YHJ42801
                        
                                            
                                            
                                            Expression system
                        
                        E. coli                        
                                                
                                            Species
                        
                        Homo sapiens (Human)                        
                                                
                                            Protein length
                        
                        Cys26-Ser138                        
                                                
                                            Predicted molecular weight
                        
                        14.62 kDa                        
                                                
                                            Nature
                        
                        Recombinant                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Endotoxin level
                        
                        Please contact with the lab for this information.                        
                                                
                                            Purity
                        
                        >90% as determined by SDS-PAGE.                        
                                                
                                            
                                            Accession
                        
                        Q99062                        
                                                
                                            
                                            Applications
                        
                        ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress                        
                                                
                                            Form
                        
                        Lyophilized                        
                                                
                                            Storage buffer
                        
                        Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.                        
                                                
                                            Reconstitution
                        
                        Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Shipping
                        
                        In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.                        
                                                
                                            Stability and Storage
                        
                        Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.                        
                                                
                                            
                                            
                                                Alternative Names
                            G-CSF receptor, CSF3R, GCSFR, G-CSF-R, CD114, Granulocyte colony-stimulating factor receptor
                            
                                                    
                                            
                                            
                                        
                 
                
                
                                            Gene Expression of CSF3R/CD114 Is Associated with Poorer Patient Survival in Glioma., PMID:38474265
                                            Specific circulating neutrophils subsets are present in clinically stable adults with cystic fibrosis and are further modulated by pulmonary exacerbations., PMID:36248793
                                            Delineation of target expression profiles in CD34+/CD38- and CD34+/CD38+ stem and progenitor cells in AML and CML., PMID:33085758
                                            Roniciclib down-regulates stemness and inhibits cell growth by inducing nucleolar stress in neuroblastoma., PMID:32737364
                                            Establishment and characterization of two head kidney macrophage cell lines from large yellow croaker (Larimichthys crocea)., PMID:31470020
                                            CSF3R/CD114 mediates infection-dependent transition to severe asthma., PMID:30312710
                                            Protective Role of Myeloid Cells Expressing a G-CSF Receptor Polymorphism in an Induced Model of Lupus., PMID:29868014
                                            Role of the angiotensin-converting enzyme in the G-CSF-induced mobilization of progenitor cells., PMID:29549541
                                            Direct anti-inflammatory effects of granulocyte colony-stimulating factor (G-CSF) on activation and functional properties of human T cell subpopulations in vitro., PMID:29357983
                                            CD114: A New Member of the Neural Crest-Derived Cancer Stem Cell Marker Family., PMID:27428599
                                            Expressions of CD96 and CD123 in Bone Marrow Cells of Patients with Myelodysplastic Syndromes., PMID:26642704
                                            CD114 Expression Mediates Melanoma Tumor Cell Growth and Treatment Resistance., PMID:26124323
                                            In vivo Lineage-tracing Studies in a Cancer Stem Cell Population in Neuroblastoma., PMID:27540563
                                            GCSF-R expression in myelodysplastic and myeloproliferative disorders and blast dysmaturation in CML., PMID:23897249
                                            G-CSF receptor positive neuroblastoma subpopulations are enriched in chemotherapy-resistant or relapsed tumors and are highly tumorigenic., PMID:23687340
                                            Defective leukocyte GM-CSF receptor (CD116) expression and function in inflammatory bowel disease., PMID:21557945
                                            Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments., PMID:21357764
                                            Physicochemical and biologic comparability of a biosimilar granulocyte colony-stimulating factor with its reference product., PMID:20873878
                                            C/EBPα and PU.1 are involved in distinct differentiation responses of acute promyelocytic leukemia HL-60 and NB4 cells via chromatin remodeling., PMID:20864248
                                            Expression of CD123 and CD114 on the bone marrow cells of patients with myelodysplastic syndrome., PMID:20819538
                                            Neutrophil adsorption by polymyxin B-immobilized fiber column for acute exacerbation in patients with interstitial pneumonia: a pilot study., PMID:20185904
                                            Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets., PMID:19712453
                                            Neutrophil hyperchemotaxis in Behçet's disease: a possible role for monocytes orchestrating bacterial-induced innate immune responses., PMID:19701803
                                            Isolation and characterization of stem cells from the human parathyroid gland., PMID:19489980
                                            Activation of critical, host-induced, metabolic and stress pathways marks neutrophil entry into cystic fibrosis lungs., PMID:19293384
                                            Neutrophil apoptosis, activation and anti-inflammatory cytokine response in granulocyte colony-stimulating factor-treated patients with community-acquired pneumonia., PMID:16369129
                                            [The response of bone marrow hematopoietic cells to G-CSF in paroxysmal nocturnal hemoglobinuria patients]., PMID:15949269
                                            Expression and prognostic value of hemopoietic cytokine receptors in acute myeloid leukemia (AML): implications for future therapeutical strategies., PMID:14962246
                                            Granulocyte colony-stimulating factor (G-CSF) downregulates its receptor (CD114) on neutrophils and induces gelatinase B release in humans., PMID:11091218
                                            Endotoxin down-modulates granulocyte colony-stimulating factor receptor (CD114) on human neutrophils., PMID:10882621
                                            Decreased apoptosis and increased activation of alveolar neutrophils in bacterial pneumonia., PMID:10858402
                                            Novel technique for the direct flow cytofluorometric analysis of human basophils in unseparated blood and bone marrow, and the characterization of phenotype and peroxidase of human basophils., PMID:10082306