Catalog No.
YHJ41501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser456-Phe765
Predicted molecular weight
38.24 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96PH1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NADPH oxidase 5, NOX5
Endothelial NADPH oxidase 5 overexpression promotes thrombosis and alters thrombus composition by sex-dependent mechanisms in mice., PMID:40436274
Synergistic Network Pharmacology: Preclinical Validation and Clinical Safety in Acute Ischemic Stroke., PMID:40371623
Characterising the role of placental angiotensin-converting enzyme 2 (ACE2) during the onset of oxidative insult by hypoxia/reoxygenation: Implications for fetal growth restriction., PMID:40222298
Integrated m6A RNA methylation and transcriptomic analysis of Apostichopus japonicus under combined high-temperature and hypoxia stress., PMID:40211154
SET7 lysine methyltransferase mediates the up-regulation of NADPH oxidase expression, oxidative stress, and NLRP3 inflammasome priming in atherosclerosis., PMID:40098010
Polydatin enhances oxaliplatin-induced cell death by activating NOX5-ROS-mediated DNA damage and ER stress in colon cancer cells., PMID:39850563
Association of NOX5 Expression with Sperm Activity and Motility in Pathospermic Infertile Men., PMID:39830324
The Impact of NADPH Oxidase 5 Activity and Reactive Oxygen Species on Capacitated Human Sperm., PMID:39830321
[Inhibition of PRDX1 protein expression and promotion of apoptosis of colorectal cancer cells by furanodienone via inducing ROS generation from NOX4-derived mitochondria]., PMID:39701785
NOX proteins and ROS generation: role in invadopodia formation and cancer cell invasion., PMID:39696702
Flavonoids and other constituents from Jacaranda mimosifolia: In vitro analysis, molecular docking, and molecular dynamic simulations of antioxidant and anti-inflammatory activities., PMID:39693906
To activate NAD(P)H oxidase with a brief pulse of photodynamic action., PMID:39655710
NADPH oxidase 5 is a novel susceptibility gene for type 2 diabetes mellitus., PMID:39529984
NADPH Oxidase 5 (NOX5) Upregulates MMP-10 Production and Cell Migration in Human Endothelial Cells., PMID:39456453
Role of NOX1 and NOX5 in protein kinase C/reactive oxygen species‑mediated MMP‑9 activation and invasion in MCF‑7 breast cancer cells., PMID:39219290
The NADPH oxidases DUOX1 and DUOX2 are sorted to the apical plasma membrane in epithelial cells via their respective maturation factors DUOXA1 and DUOXA2., PMID:39126279
Orthologs of NOX5 and EC-SOD/SOD3: dNox and dSod3 Impact Egg Hardening Process and Egg Laying in Reproductive Function of Drosophila melanogaster., PMID:38892326
Polydatin, a potential NOX5 agonist, synergistically enhances antitumor activity of cisplatin by stimulating oxidative stress in non‑small cell lung cancer., PMID:38873997
Structural basis of human NOX5 activation., PMID:38734761
Proteasome inhibitors induce apoptosis by superoxide anion generation via NADPH oxidase 5 in human neuroblastoma SH-SY5Y cells., PMID:38677786
Correction for: Inhibition of circulating exosomal microRNA-15a-3p accelerates diabetic wound repair., PMID:38647435
Gene Expression and Prognostic Value of NADPH Oxidase Enzymes in Breast Cancer., PMID:38542437
NADPH oxidase 1 promotes hepatic steatosis in obese mice and is abrogated by augmented skeletal muscle mass., PMID:38258487
Long non-coding RNA FKSG29 regulates oxidative stress and endothelial dysfunction in obstructive sleep apnea., PMID:37914826
A novel monoclonal antibody reveals the enrichment of NADPH oxidase 5 in human splenic endothelial cells., PMID:37821487
NOX family NADPH oxidases in mammals: Evolutionary conservation and isoform-defining sequences., PMID:37595375
Endothelial NOX5 overexpression induces changes in the cardiac gene profile: potential impact in myocardial infarction?, PMID:37566320
Regorafenib induces NOX5-mediated endoplasmic reticulum stress and potentiates the anti-tumor activity of cisplatin in non-small cell lung cancer cells., PMID:36940556
Identification of candidate genomic regions for egg yolk moisture content based on a genome-wide association study., PMID:36918797
Structure, regulation, and physiological functions of NADPH oxidase 5 (NOX5)., PMID:36905456
Sulodexide Prevents Hyperglycemia-Induced Endothelial Dysfunction and Oxidative Stress in Porcine Retinal Arterioles., PMID:36829947
Functional interactions between NADPH oxidase 5 and actin., PMID:36776559
Ca2+ -binding-region-dependent cell surface localization of NADPH oxidase Nox5., PMID:36653838
NAADP-Evoked Ca2+ Signaling: The DUOX2-HN1L/JPT2-Ryanodine Receptor 1 Axis., PMID:36443544
NADPH Oxidase 5 (NOX5) Overexpression Promotes Endothelial Dysfunction via Cell Apoptosis, Migration, and Metabolic Alterations in Human Brain Microvascular Endothelial Cells (hCMEC/D3)., PMID:36358519
NOX2 and NOX5 are increased in cardiac microvascular endothelium of deceased COVID-19 patients., PMID:36332749
NADPH Oxidase Isoforms in COPD Patients and Acute Cigarette Smoke-Exposed Mice: Induction of Oxidative Stress and Lung Inflammation., PMID:36009258
α-Iso-cubebene attenuates neointima formation by inhibiting HMGB1-induced monocyte to macrophage differentiation via suppressing ROS production., PMID:35940074
Endothelial reactive oxygen-forming NADPH oxidase 5 is a possible player in diabetic aortic aneurysm but not atherosclerosis., PMID:35798762
Antiaging effect of inotodiol on oxidative stress in human dermal fibroblasts., PMID:35759867
Malaria oocysts require circumsporozoite protein to evade mosquito immunity., PMID:35680915
Impact of calcium and reactive oxygen species on human sperm function: Role of NOX5., PMID:35679508
Development of a caffeic acid-phthalimide hybrid compound for NADPH oxidase inhibition., PMID:35480205
Prednisone Ameliorates Atrial Inflammation and Fibrosis in Atrial Tachypacing Dogs., PMID:35296611
Independent of Renox, NOX5 Promotes Renal Inflammation and Fibrosis in Diabetes by Activating ROS-Sensitive Pathways., PMID:35275988
Oxidative Properties of Blood-Derived Extracellular Vesicles in 15 Patients After Myocardial Infarction., PMID:35241639
Calmodulin binding to the dehydrogenase domain of NADPH oxidase 5 alters its oligomeric state., PMID:35079639
Endothelial NOX5 Expression Modulates Thermogenesis and Lipolysis in Mice Fed with a High-Fat Diet and 3T3-L1 Adipocytes through an Interleukin-6 Dependent Mechanism., PMID:35052534
Beneficial effects of PCSK9 inhibition with alirocumab in familial hypercholesterolemia involve modulation of new immune players., PMID:34864314
The evolutionary origins of peroxynitrite signalling., PMID:34638028
For research use only. Not for human or drug use.
