Catalog No.
YHJ40701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys368-Ser541
Predicted molecular weight
22.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96MK3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Pseudokinase FAM20A, FAM20A
Truncated Variants in FAM20A and WDR72 Genes Underlie Autosomal Recessive Amelogenesis Imperfecta in Four Pakistani Families., PMID:40108106
The craniofacial, dental and systemic manifestations of Enamel Renal Syndrome: A Scoping review., PMID:40089179
A transgenic mouse line with a 58 kb fragment deletion shows skeletal defects., PMID:39915545
Genetic Variants Associated with the Biochemical Response to Vitamin D3 in the Multi-Ethnic Study of Atherosclerosis., PMID:39815761
Molecular Study of FAM20A Gene and Biochemical Analysis for Amelogenesis Imperfecta Patients., PMID:39661899
Biomarkers associated with papillary thyroid carcinoma and Hashimoto's thyroiditis: Bioinformatic analysis and experimental validation., PMID:39510033
A case of enamel renal syndrome from a novel genetic mutation, multidisciplinary management and long-term prognosis., PMID:39376587
Abnormal dental follicle cells: A crucial determinant in tooth eruption disorders (Review)., PMID:39027997
FAM20A: a potential diagnostic biomarker for lung squamous cell carcinoma., PMID:38983866
Enamel Renal Gingival Syndrome in an Adolescent., PMID:38671566
Gingival proteomics reveals the role of TGF beta and YAP/TAZ signaling in Raine syndrome fibrosis., PMID:38664418
FAM20A-Associated Amelogenesis Imperfecta: Gene Variants with Functional Verification and Histological Features., PMID:38546520
FAM20A is a golgi-localized Type II transmembrane protein., PMID:38499693
In-depth investigation of FAM20A insufficiency effects on deciduous dental pulp cells: Altered behaviours, osteogenic differentiation, and inflammatory gene expression., PMID:38477421
The 'analysis of gene expression and biomarkers for point-of-care decision support in Sepsis' study; temporal clinical parameter analysis and validation of early diagnostic biomarker signatures for severe inflammation andsepsis-SIRS discrimination., PMID:38332914
CRISPR/Cas9-Induced Fam83h Knock-out Leads to Impaired Wnt/β-Catenin Pathway and Altered Expression of Tooth Mineralization Genes in Mice., PMID:38269199
Authors' reply to: Deep dental phenotyping and a novel FAM20A variant in patients with amelogenesis imperfecta type IG., PMID:37794759
Comment on: Deep dental phenotyping and a novel FAM20A variant in patients with amelogenesis imperfecta type IG., PMID:37743631
Epithelial-specific deletion of FAM20A leads to short root defects., PMID:37625561
Association between malocclusions and amelogenesis imperfecta genotype and phenotype: A systematic review., PMID:37494776
Genotype-phenotype analysis of selective failure of tooth eruption-A systematic review., PMID:37448157
FAM20A mutations and transcriptome analyses of dental pulp tissues of enamel renal syndrome., PMID:37159186
Deep dental phenotyping and a novel FAM20A variant in patients with amelogenesis imperfecta type IG., PMID:36650945
Hypoplastic amelogenesis imperfecta, bilateral nephrolithiasis and FGF-23-mediated hypophosphataemia: a triad of FAM20A-related enamel renal syndrome., PMID:36351670
Recognition of a Novel Gene Signature for Human Glioblastoma., PMID:35456975
The effect and mechanism of gene Fam20a on the development and function of salivary glands in mice., PMID:35278791
Assessment of Zearalenone-Induced Cell Survival and of Global Gene Regulation in Mouse TM4 Sertoli Cells., PMID:35202126
Seven Genes Associated With Lymphatic Metastasis in Thyroid Cancer That Is Linked to Tumor Immune Cell Infiltration., PMID:35141140
Quantification of FAM20A in human milk and identification of calcium metabolism proteins., PMID:34957696
Pathogenesis of Enamel-Renal Syndrome Associated Gingival Fibromatosis: A Proteomic Approach., PMID:34777248
Identification of key genes in calcific aortic valve disease via weighted gene co-expression network analysis., PMID:34020624
The ABCs of the atypical Fam20 secretory pathway kinases., PMID:33759783
Differential alternative splicing between hepatocellular carcinoma with normal and elevated serum alpha-fetoprotein., PMID:33371894
Two new families with enamel renal syndrome: A novel FAM20A gene mutation and review of literature., PMID:32835847
Discovery of Selenocysteine as a Potential Nanomedicine Promotes Cartilage Regeneration With Enhanced Immune Response by Text Mining and Biomedical Databases., PMID:32792959
The genomic profile of parathyroid carcinoma based on whole-genome sequencing., PMID:32574388
Four novel mutations of FAM20A in amelogenesis imperfecta type IG and review of literature for its genotype and phenotype spectra., PMID:32246227
FAM20A is essential for amelogenesis, but is dispensable for dentinogenesis., PMID:31667691
A novel FAM20C mutation causes a rare form of neonatal lethal Raine syndrome., PMID:31297960
Multiple Modes of Vitamin K Actions in Aging-Related Musculoskeletal Disorders., PMID:31212662
Transcriptome analysis of gingival tissues of enamel-renal syndrome., PMID:31131889
A potential new approach for treating systemic sclerosis: Dedifferentiation of SSc fibroblasts and change in the microenvironment by blocking store-operated Ca2+ entry., PMID:30870448
Enamel renal syndrome: A novel homozygous FAM20A founder mutation in 5 new Brazilian families., PMID:30394349
Analysis of Polymorphisms in Genes Differentially Expressed in the Enamel of Mice with Different Genetic Susceptibilities to Dental Fluorosis., PMID:30149392
Candidate gene sequencing reveals mutations causing hypoplastic amelogenesis imperfecta., PMID:30120606
Physicochemical analysis of human pulpal mineralization secondary to FAM20A mutations., PMID:29745815
Structure and evolution of the Fam20 kinases., PMID:29572475
Nephrocalcinosis in Amelogenesis Imperfecta Caused by the FAM20A Mutation., PMID:29439260
Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding., PMID:28432788
Periodontal disease and FAM20A mutations., PMID:28298625
For research use only. Not for human or drug use.
