Catalog No.
YHJ38901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro377-Phe534
Predicted molecular weight
20.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96F46
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IL17R, CDw217, IL-17RA, Interleukin-17 receptor A, IL-17 receptor A, IL17RA, CD217
Innovative peptide therapeutics targeting IL17RA to regulate inflammatory responses., PMID:40121226
Deciphering the role of IL17RA in psoriasis and chronic mucocutaneous candidiasis: shared pathways and distinct manifestations., PMID:39911581
Interleukin 17 RA and RC gene polymorphisms and increased preeclampsia risk: Single and combined genetic analysis., PMID:39908641
Bidirectional interaction between IL and 17A/IL-17RA pathway dysregulation and α-synuclein in the pathogenesis of Parkinson's disease., PMID:39461385
IL-17RA/CTSK axis mediates H. pylori-induced castration-resistant prostate cancer growth., PMID:39424989
Deep hematologic response to RD treatment in patients with multiple myeloma is associated with overexpression of IL-17R in CD138+ plasma cells., PMID:39384864
Role and functional mechanisms of IL‑17/IL‑17R signaling in pancreatic cancer (Review)., PMID:39219271
Recurrent subcutaneous abscesses and pneumonia in a toddler with a novel pathogenic variation in IL-17RA gene., PMID:39179263
Involvement of IL17A and IL17RA variants in interleukin-17A levels and disease activity in ulcerative colitis., PMID:39111114
Efficacy and Safety of Brodalumab, an Anti-interleukin-17 Receptor A Monoclonal Antibody, for Palmoplantar Pustulosis: 16-Week Results of a Randomized Clinical Trial., PMID:38954226
Decreased interleukin-17RA expression is associated with good prognosis in patients with colorectal cancer and inhibits tumor growth and vascularity in mice., PMID:38491831
Suppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory feedback cycle involving IL-17RA/IL-17RE epidermal signaling., PMID:38470486
Genetic association between interleukin-17 and susceptibility to rheumatoid arthritis., PMID:37926850
Mechanistic Insights into the Roles of the IL-17/IL-17R Families in Pancreatic Cancer., PMID:37686343
Association between IL-17F, IL-17RA Gene Polymorphisms and Response to Biological Drugs in Psoriasis and Beyond., PMID:37239484
Immunogenic Cell Death Associated Molecular Patterns and the Dual Role of IL17RA in Interstitial Cystitis/Bladder Pain Syndrome., PMID:36979355
IL17A and IL17RA gene polymorphisms in Fanconi anemia., PMID:36790253
Associations of IL-17 and IL-17 receptor polymorphisms with Behçet's disease in Denizli Province of Turkey., PMID:36701075
lncRNA IL-17RA-1 Attenuates LPS-Induced Sepsis via miR-7847-3p/PRKCG-Mediated MAPK Signaling Pathway., PMID:36274974
Evaluation of interleukin-17 receptor (IL-17RA) gene expression in PBMCs of patients with premature coronary artery disease., PMID:35913009
Serum IL-17A concentration and a IL17RA single nucleotide polymorphism contribute to the risk of autoimmune type 1 diabetes., PMID:35583128
Cardiomyocyte IL-1R2 protects heart from ischemia/reperfusion injury by attenuating IL-17RA-mediated cardiomyocyte apoptosis., PMID:35087030
Single-cell RNA sequencing deconvolutes the in vivo heterogeneity of human bone marrow-derived mesenchymal stem cells., PMID:34803492
Association between IL-17A, IL-17F and IL-17RA gene polymorphisms and susceptibility to psoriasis and psoriatic arthritis: a meta-analysis., PMID:34705056
Cutting Edge: Intestinal IL-17A Receptor Signaling Specifically Regulates High-Fat Diet-Mediated, Microbiota-Driven Metabolic Disorders., PMID:34544802
Increased IL-23R+ Th Cells Population Exhibits Higher SLEDAI-2K Scores in Systemic Lupus Erythematosus Patients., PMID:34484186
Interleukin-17A Triggers the Release of Platelet-Derived Factors Driving Vascular Endothelial Cells toward a Pro-Angiogenic State., PMID:34440624
IL-23/IL-17 axis and soluble receptors isoforms sIL-23R and sIL-17RA in patients with rheumatoid arthritis-presenting periodontitis., PMID:34403509
Polymorphisms at the IL17A and IL17RA Genes are Associated with Prognosis of Papillary Thyroid Carcinoma., PMID:34384609
From Messengers to Receptors in Psoriasis: The Role of IL-17RA in Disease and Treatment., PMID:34201664
The expression of IL17RA on sputum macrophages in asthma patients., PMID:33840588
Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis., PMID:33789737
Exploring genetic defects in adults who were clinically diagnosed as severe combined immune deficiency during infancy., PMID:33599911
TH17/IL23 cytokine gene polymorphisms in bullous pemphigoid., PMID:33340282
[IL-17A/lL-17RA reduces cisplatin sensitivity of ovarian cancer SKOV3 cells by regulating autophagy]., PMID:33243748
Brodalumab in psoriatic arthritis: results from the randomised phase III AMVISION-1 and AMVISION-2 trials., PMID:33106286
Discovery of novel immunopharmacological ligands targeting the IL-17 inflammatory pathway., PMID:33045560
Interleukin 17 receptor A haplotype analysis in chronic spontaneous urticaria: A preliminary study., PMID:32969586
IL17RA in early-onset coronary artery disease: Total leukocyte transcript analysis and promoter polymorphism (rs4819554) association., PMID:32950026
Two dimensional proteomic analysis of serum shows immunological proteins exclusively expressed in sulfur mustard exposed patients with long term pulmonary complications., PMID:32853926
One-Year Pharmacovigilance Update of Brodalumab., PMID:32845586
Rosmarinic acid inhibits migration, invasion, and p38/AP-1 signaling via miR-1225-5p in colorectal cancer cells., PMID:32838607
Dual neutralisation of IL-17F and IL-17A with bimekizumab blocks inflammation-driven osteogenic differentiation of human periosteal cells., PMID:32723833
Systematic analysis of the IL-17 receptor signalosome reveals a robust regulatory feedback loop., PMID:32696476
IL17RA variations showed no associations with post-bronchiolitis asthma or lung function., PMID:32654355
Short-term effectiveness of biologics in patients with moderate-to-severe plaque psoriasis: A systematic review and network meta-analysis., PMID:32600737
Genetic polymorphism in IL17RA induces susceptibility to Toxoplasma gondii infection in Brazilian pregnant women., PMID:32598917
Impact of IL-17F 7488T/C Functional Polymorphism on Progressive Rheumatoid Arthritis: Novel Insight from the Molecular Dynamic Simulations., PMID:32543936
Expression Levels of IL-17A, IL-17F, IL-17RA, and IL-17RC in Prostate Cancer with Taking into Account the Histological Grade according to Gleason Scale in Comparison to Benign Prostatic Hyperplasia: In Search of New Therapeutic Options., PMID:32537467
Loss of IL-27Rα Results in Enhanced Tubulointerstitial Fibrosis Associated with Elevated Th17 Responses., PMID:32522836
For research use only. Not for human or drug use.
