Catalog No.
YHJ37301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser19-Cys220
Predicted molecular weight
24.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96AX2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ras-related protein Rab-37, RAB37
Novel therapeutic targets for metabolism-related diseases: proteomic Mendelian randomization and colocalization analyses., PMID:40453312
GDP-bound Rab37 modulates M2-like tumor-associated macrophage polarization by attenuating STAT1 translocation to downregulate the type I IFN pathway., PMID:39984679
RAB37 suppresses the EMT, migration and invasion of gastric cancer cells by mediating autophagic degradation of β-catenin., PMID:39699800
Identification of Long Non-Coding RNA as Potential Biomarkers for the Diagnosis of Postmenopausal Osteoporosis., PMID:39619600
RAB37-mediated autophagy guards ovarian homeostasis and function., PMID:39113565
Revealing potential Rab proteins participate in regulation of secretory autophagy machinery., PMID:38804615
IL-33/NF-κB/ST2L/Rab37 positive-feedback loop promotes M2 macrophage to limit chemotherapeutic efficacy in lung cancer., PMID:38778059
RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation., PMID:38536817
Incubation of methamphetamine craving in punishment-resistant individuals is associated with activation of specific gene networks in the rat dorsal striatum., PMID:38351172
Rab37 mediates trafficking and membrane presentation of PD-1 to sustain T cell exhaustion in lung cancer., PMID:38321486
Secretory autophagy-promoted cargo exocytosis requires active RAB37., PMID:37151129
Rab37 Promotes Endothelial Differentiation and Accelerates ADSC-Mediated Diabetic Wound Healing through Regulating Secretion of Hsp90α and TIMP1., PMID:36627432
The complex, dynamic SpliceOme of the small GTPase transcripts altered by technique, sex, genetics, tissue specificity, and RNA base editing., PMID:36467401
Secretory autophagy promotes Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1., PMID:36457117
iPSCs derived from esophageal atresia patients reveal SOX2 dysregulation at the anterior foregut stage., PMID:36317486
Identification of potential biomarkers and pathways associated with carotid atherosclerotic plaques in type 2 diabetes mellitus: A transcriptomics study., PMID:36187128
Secretory autophagy promotes RAB37-mediated insulin secretion under glucose stimulation both in vitro and in vivo., PMID:36109708
Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells., PMID:35649370
Knockout of GGPPS1 restrains rab37-mediated autophagy in response to ventilator-induced lung injury., PMID:35334098
The Combined Model of CX3CR1-Related Immune Infiltration Genes to Evaluate the Prognosis of Idiopathic Pulmonary Fibrosis., PMID:35222428
Identification of key tumor stroma-associated transcriptional signatures correlated with survival prognosis and tumor progression in breast cancer., PMID:35020130
Targeting protumor factor chitinase-3-like-1 secreted by Rab37 vesicles for cancer immunotherapy., PMID:34987649
RAB37 Promotes Adipogenic Differentiation of hADSCs via the TIMP1/CD63/Integrin Signaling Pathway., PMID:34858503
Pan-Cancer Analysis Reveals Common and Specific Relationships between Intragenic miRNAs and Their Host Genes., PMID:34572448
Converged Rab37/IL-6 trafficking and STAT3/PD-1 transcription axes elicit an immunosuppressive lung tumor microenvironment., PMID:34093869
RAB37 multiple alleles, transcription activation and evolution in mammals., PMID:33061809
Methionine represses the autophagy of gastric cancer stem cells via promoting the methylation and phosphorylation of RAB37., PMID:32926650
Immune-Related Hub Genes and the Competitive Endogenous RNA Network in Alzheimer's Disease., PMID:32925027
DNA methylation-based diagnostic and prognostic biomarkers of nasopharyngeal carcinoma patients., PMID:32541515
Toxicological effects of ambient fine (PM2.5-0.18) and ultrafine (PM0.18) particles in healthy and diseased 3D organo-typic mucocilary-phenotype models., PMID:31344532
VAMP8, a vesicle-SNARE required for RAB37-mediated exocytosis, possesses a tumor metastasis suppressor function., PMID:30165196
Rab37 mediates exocytosis of secreted frizzled-related protein 1 to inhibit Wnt signaling and thus suppress lung cancer stemness., PMID:30158579
RAB37 Hypermethylation Regulates Metastasis and Resistance to Docetaxel-Based Induction Chemotherapy in Nasopharyngeal Carcinoma., PMID:30131385
Rab37 in lung cancer mediates exocytosis of soluble ST2 and thus skews macrophages toward tumor-suppressing phenotype., PMID:29717487
The small GTPase RAB37 functions as an organizer for autophagosome biogenesis., PMID:29388490
Phosphorylation of Rab37 by protein kinase C alpha inhibits the exocytosis function and metastasis suppression activity of Rab37., PMID:29312551
RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly., PMID:29229996
Whole exome sequencing in thrombophilic pedigrees to identify genetic risk factors for venous thromboembolism., PMID:29117201
Recycling endosomes in human cytotoxic T lymphocytes constitute an auxiliary intracellular trafficking pathway for newly synthesized perforin., PMID:28822075
Dysregulation of Rab37-Mediated Cross-talk between Cancer Cells and Endothelial Cells via Thrombospondin-1 Promotes Tumor Neovasculature and Metastasis., PMID:28151721
HIV-1 Nef Impairs the Formation of Calcium Membrane Territories Controlling the Signaling Nanoarchitecture at the Immunological Synapse., PMID:27798165
Mast cell degranulation is negatively regulated by the Munc13-4-binding small-guanosine triphosphatase Rab37., PMID:26931073
Proteomic analysis of three gonad types of swamp eel reveals genes differentially expressed during sex reversal., PMID:25985063
Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood., PMID:25861810
Small GTPase Rab37 targets tissue inhibitor of metalloproteinase 1 for exocytosis and thus suppresses tumour metastasis., PMID:25183545
The GTPase Rab37 Participates in the Control of Insulin Exocytosis., PMID:23826383
An association study on genetic polymorphisms of Rab37 gene with the risk of esophageal squamous cell carcinoma in a Chinese Han population., PMID:23372429
A complete Rab screening reveals novel insights in Weibel-Palade body exocytosis., PMID:22899725
Disruption of Wnt planar cell polarity signaling by aberrant accumulation of the MetAP-2 substrate Rab37., PMID:22035799
Release of TNF-α from macrophages is mediated by small GTPase Rab37., PMID:21805469
For research use only. Not for human or drug use.
