Catalog No.
DHC00101
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Humanized
Isotype
IgG1-kappa
Clonality
Monoclonal
Target
APCS, PTX2, Serum amyloid P-component, 9.5S alpha-1-glycoprotein, SAP
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P02743
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
GSK-2398852, CAS: 1662664-56-3
Clone ID
Dezamizumab
Novel methods to determine complement activation in human serum induced by the complex of Dezamizumab and serum amyloid P, PMID: 34461096
The Pentraxins 1975-2018: Serendipity, Diagnostics and Drugs, PMID: 30459761
Monoclonal antibodies in the treatment of AL amyloidosis: co-targetting the plasma cell clone and amyloid deposits, PMID: 32072615
Repeat doses of antibody to serum amyloid P component clear amyloid deposits in patients with systemic amyloidosis, PMID: 29298867
An observational, non-interventional study for the follow-up of patients with amyloidosis who received miridesap followed by dezamizumab in a phase 1 study., PMID:35810311
Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study., PMID:35152886
Novel methods to determine complement activation in human serum induced by the complex of Dezamizumab and serum amyloid P., PMID:34461096
Monoclonal antibodies in the treatment of AL amyloidosis: co-targetting the plasma cell clone and amyloid deposits., PMID:32072615
The Pentraxins 1975-2018: Serendipity, Diagnostics and Drugs., PMID:30459761
Repeat doses of antibody to serum amyloid P component clear amyloid deposits in patients with systemic amyloidosis., PMID:29298867
For research use only. Not for human or drug use.
