Catalog No.
YHJ36401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile279-Leu398
Predicted molecular weight
15.31 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q969F8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KiSS-1R, G-protein coupled receptor 54, KiSS-1 receptor, GPR54, KISS1R, hOT7T175, G-protein coupled receptor OT7T175, Metastin receptor, Hypogonadotropin-1, AXOR12, Kisspeptins receptor
Kisspeptin-54 Restores Blood-Brain Barrier Integrity via GATA-4 in Ischemic Stroke., PMID:40454669
Kisspeptin Receptor Agonists and Antagonists: Strategies for Discovery and Implications for Human Health and Disease., PMID:40430029
Maternal cafeteria diet adversely affects the reproductive parameters of rat offspring in a sex-specific manner., PMID:40420282
Kisspeptin-10 Prevents the Development of Cerebral Aneurysms by Reducing the Expression of Egr-1., PMID:40384564
Adult Neurogenesis Is Regulated by the Endocannabinoid and Kisspeptin Systems., PMID:40362219
AMH and Kisspeptin Receptor Expression in Rare Hydropic Leiomyoma: A Case Study., PMID:40305440
Kisspeptin isoforms: versatile players in reproduction and beyond., PMID:40271959
In vivo effects of NPFF and NPAF peptides on gene expression in the brain-pituitary-gonadal axis of female half-smooth tongue soles., PMID:40268205
Genetic variants of the DLK1, KISS1R, MKRN3 genes in girls with precocious puberty., PMID:40264804
Kisspeptin 10 Inhibited the Proliferation, Migration, and Stemness of Esophageal Cancer Cells via Regulating the SIX1/Wnt/β-Catetin Signaling., PMID:40192612
Central lipid sensing pathways contribute to the control of puberty and its alterations in conditions of obesity., PMID:40172224
Sex-related gene expression in the posterodorsal medial amygdala of cycling female rats along with prolactin modulation of lordosis behavior., PMID:40147695
Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control., PMID:40065551
New Insights in Bovine Follicular Cysts., PMID:40056005
Anatomic distribution of kisspeptin neurons in the adult sheep amygdala: Associations with sex, estrogen receptor alpha, androgen receptor, and sexual partner preference., PMID:40033683
Critical role of arcuate nucleus kisspeptin and Kiss1R in regulation of the ovine luteinizing hormone surge., PMID:40033679
Photoperiod-driven testicular DNA methylation in gonadotropin and sex steroid receptor promoters in Siberian hamsters., PMID:39954063
Fluvoxamine Inhibited NLRP3 and NF-κB Inflammatory Pathways and Maintained Genital Functions by Ameliorating CD-MPR, KISS-1, AQP4 and Claudin-1 Expressions., PMID:39891570
Kisspeptin control of hypothalamus-pituitary-ovarian functions., PMID:39864941
Hypothyroidism Alters Uterine Kisspeptin System and Activity Modulators in Cyclic Rats., PMID:39859259
Synthesis and characterisation of DOTA-kisspeptin-10 as a potential gallium-68/lutetium-177 pan-tumour radiopharmaceutical., PMID:39775975
Design and implication of a breast cancer-targeted drug delivery system utilizing the Kisspeptin/GPR54 system., PMID:39755342
Expression of GnRH, Kisspeptin, and Their Specific Receptors in the Ovary and Uterus in Deslorelin-Treated Late-Prepubertal Bitches., PMID:39728931
Locked Dimerized CXCL12 Exerts Radiosensitizing Effects in Head and Neck Cancer., PMID:39722591
Multiple effects of kisspeptin on neuroendocrine, reproduction, and metabolism in polycystic ovary syndrome., PMID:39694850
Kisspeptin participates in the positive reward state induced by paced mating and modulates sexual receptivity and paced mating behavior in female rats., PMID:39637765
Recurrent spontaneous ovarian hyperstimulation in a young nonpregnant Chinese woman with Rathke cleft cyst and a KISS1R variant: A rare case report and literature review., PMID:39620881
The antidepressant-like effects of kisspeptin-10 are reversed by kisspeptin antagonist peptide 234 in male rats., PMID:39605118
Gpr54 deletion accelerates hair cycle and hair regeneration., PMID:39587329
Kiss1 receptor knockout exacerbates airway hyperresponsiveness and remodeling in a mouse model of allergic asthma., PMID:39468619
Kisspeptin Alleviates Human Hepatic Fibrogenesis by Inhibiting TGFβ Signaling in Hepatic Stellate Cells., PMID:39404414
Comprehensive Study on Central Precocious Puberty: Molecular and Clinical Analyses in 90 Patients., PMID:39324648
Reduced voluntary wheel running behaviour in Kiss1r knockout mice., PMID:39317294
Interactions between kisspeptin and bone: Cellular mechanisms, clinical evidence, and future potential., PMID:39269749
Homozygous mutation of KISS1 receptor (KISS1R) gene identified in a Chinese patient with congenital hypogonadotropic hypogonadism (CHH): case report and literature review., PMID:39262158
Identification of Environmental Compounds That May Trigger Early Female Puberty by Activating Human GnRHR and KISS1R., PMID:39254333
Spexin and its receptors in the yellowtail kingfish (Seriola lalandi): identification, expression profiles and reproductive function., PMID:39207579
Comprehensive Analysis of Kisspeptin Signaling: Effects on Cellular Dynamics in Cervical Cancer., PMID:39199311
Structural basis for the ligand recognition and G protein subtype selectivity of kisspeptin receptor., PMID:39151001
Genome sequencing reveals novel causative structural and single nucleotide variants in Pakistani families with congenital hypogonadotropic hypogonadism., PMID:39143522
Effects of prenatal stress on reproductive function of male offspring through the KISS1 system., PMID:39140811
Jiawei Buzhong Yiqi Decoction attenuates polycystic ovary syndrome through regulating kisspeptin-GPR54-AKT-SHBG system., PMID:39116604
Kisspeptin expression levels in patients with placenta previa: A randomized trial., PMID:38996103
The role of placental kisspeptin in trophoblast invasion and migration: an assessment in Kiss1r knockout mice, BeWo cell lines and human term placenta., PMID:38976640
Structural basis for hormone recognition and distinctive Gq protein coupling by the kisspeptin receptor., PMID:38935498
Genetic Variants in KNDy Pathway Lack Association with Premature Ovarian Insufficiency in Mexican Women: A Sequencing-Based Cohort Study., PMID:38927724
Kisspeptin signalling and its correlation with placental ultrastructure and clinical outcomes in pregnant South African women with obesity and gestational diabetes., PMID:38878622
The role of KNDy neurons in human reproductive health., PMID:38866494
Kisspeptin signaling in astrocytes modulates the reproductive axis., PMID:38861336
Restoring function to inactivating G protein-coupled receptor variants in the hypothalamic-pituitary-gonadal axis1., PMID:38852954