Catalog No.
YHJ35501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His545-Met716
Predicted molecular weight
44.91 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92997
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dishevelled-3, DVL3, Segment polarity protein dishevelled homolog DVL-3, DSH homolog 3, KIAA0208
LRRFIP1 enhances the Wnt/β-catenin pathway by binding to DVLs in myelodysplastic syndrome., PMID:40420163
A de novo microdeletion of 3q27.1-3q27.2 causing fetal growth retardation: a case report and literature review., PMID:40386355
Impact of MiRNAs on Wnt-related gene activity in breast cancer., PMID:40346182
Rac1 and Nectin3 are essential for planar cell polarity-directed axon guidance in the peripheral auditory system., PMID:40207531
Eurycomalactone switched hepatocellular carcinoma cells into quiescence through 5'tRFAla/DVL/β-catenin pathway inhibition., PMID:40128187
Genistein alleviates rheumatoid arthritis by inhibiting fibroblast-like synovial exosome secretion regulated by the Rab27/nSMase2/Mfge8 pathway., PMID:39895262
Identification of novel cytoskeleton protein involved in spermatogenic cells and sertoli cells of non-obstructive azoospermia based on microarray and bioinformatics analysis., PMID:39863862
PNPO-Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β-Catenin Pathway., PMID:39656865
SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation., PMID:39417621
Exploring DIX-DIX Homo- and Hetero-Oligomers in Wnt Signaling with AlphaFold2., PMID:39404409
Carboxy-terminal polyglutamylation regulates signaling and phase separation of the Dishevelled protein., PMID:39349846
WNT5B promotes the malignant phenotype of non-small cell lung cancer via the FZD3-DVL3-RAC1-PCP-JNK pathway., PMID:39094673
The Role of NOTCH Pathway Genes in the Inherited Susceptibility to Aortic Stenosis., PMID:39057646
Temporin-GHaK Exhibits Antineoplastic Activity against Human Lung Adenocarcinoma by Inhibiting the Wnt Signaling Pathway through miRNA-4516., PMID:38930863
Dishevelled Segment Polarity Protein 3 (DVL3) Induced by Bacterial LPS Promotes the Proliferation and Migration of Prostate Cancer Cells through the TLR4 Pathway., PMID:38583012
SMYD4 monomethylates PRMT5 and forms a positive feedback loop to promote hepatocellular carcinoma progression., PMID:38438251
Ginsenoside Rg3 suppresses vasculogenic mimicry by impairing DVL3-maintained stemness via PAAD cell-derived exosomal miR-204 in pancreatic adenocarcinoma., PMID:38350242
Validation of a Proteomic-Based Prognostic Model for Breast Cancer and Immunological Analysis., PMID:38145160
Delivery of microRNA-423-5p by exosome from adipose-derived stem/stromal cells inhibits DVL3 to potentiate autologous fat graft survival through adipogenesis and inflammatory response., PMID:38040867
The Wnt/β-catenin pathway is involved in 2,5-hexanedione-induced ovarian granulosa cell cycle arrest., PMID:37995618
Dishevelled Segment Polarity Protein 3: A Novel Prognosis-related Marker in Pan-driver-gene-negative Lung Adenocarcinoma., PMID:37859822
Disheveled-1 Interacts with Claudin-5 and Contributes to Norrin-Induced Endothelial Barrier Restoration., PMID:37830616
Presenilin-2 knock-In mice show severe depressive behavior via DVL3 downregulation., PMID:37501340
RNA-binding Protein QKI Inhibits Osteogenic Differentiation Via Suppressing Wnt Pathway., PMID:37460362
Identification of the hub genes in polycystic ovary syndrome based on disease-associated molecule network., PMID:37342921
Disheveled3 enhanced EMT and cancer stem-like cells properties via Wnt/β-catenin/c-Myc/SOX2 pathway in colorectal cancer., PMID:37147666
ASPM Activates Hedgehog and Wnt Signaling to Promote Small Cell Lung Cancer Stemness and Progression., PMID:36638332
Immunological classification of hepatitis B virus-positive hepatocellular carcinoma by transcriptome analysis., PMID:36618328
RNA-Binding Protein MEX3A Interacting with DVL3 Stabilizes Wnt/β-Catenin Signaling in Endometrial Carcinoma., PMID:36614043
Circadian gene CSNK1D promoted the progression of hepatocellular carcinoma by activating Wnt/β-catenin pathway via stabilizing Dishevelled Segment Polarity Protein 3., PMID:36460966
DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer., PMID:35965516
Hsa-miR-143-3p inhibits Wnt-β-catenin and MAPK signaling in human corneal epithelial stem cells., PMID:35794158
DVL1 and DVL3 require nuclear localisation to regulate proliferation in human myoblasts., PMID:35589804
E2F1-activated LINC01224 drives esophageal squamous cell carcinoma cell malignant behaviors via targeting miR-6884-5p/DVL3 axis and activating Wnt/β-catenin signaling pathway., PMID:35576835
De novo variants of CSNK2B cause a new intellectual disability-craniodigital syndrome by disrupting the canonical Wnt signaling pathway., PMID:35571680
Exosomal Dvl3 promoted the aggressive phenotypic transformation of RA-FLS via wnt pathway., PMID:35499309
Construction and Validation of a Protein-associated Prognostic Model for Gastrointestinal Cancer., PMID:35430986
Circ_0101802 Facilitates Colorectal Cancer Progression Depending on the Regulation of miR-665/DVL3 Signaling., PMID:35314912
The Gender-Specific Interaction of DVL3 and GSK3β Polymorphisms on Major Depressive Disorder Susceptibility in a Chinese Han Population: A Case-Control Study., PMID:35126809
PCP Protein Inversin Regulates Testis Function Through Changes in Cytoskeletal Organization of Actin and Microtubules., PMID:35106541
Novel pathogenic variants and quantitative phenotypic analyses of Robinow syndrome: WNT signaling perturbation and phenotypic variability., PMID:35047859
Dishevelled coordinates phosphoinositide kinases PI4KIIIα and PIP5KIγ for efficient PtdInsP2 synthesis., PMID:34982154
A Proteomics Study of the Subacute Toxicity of Rat Brain after Long- Term Exposure of Gelsemium elegans., PMID:34886788
Aberrant expression of SFRP1, SFRP3, DVL2 and DVL3 Wnt signaling pathway components in diffuse gastric carcinoma., PMID:34691249
Protein tyrosine kinase 7-knockdown inhibits oral squamous cell carcinoma cell viability, proliferation, migration and invasion via downregulating dishevelled segment polarity protein 3 expression., PMID:34659518
Personalised Medicine for Colorectal Cancer Using Mechanism-Based Machine Learning Models., PMID:34576133
MicroRNA Dysregulation in the Hippocampus of Rats with Noise-Induced Hearing Loss., PMID:34527169
Chondrocyte Polarity During Endochondral Ossification Requires Protein-Protein Interactions Between Prickle1 and Dishevelled2/3., PMID:34423861
Identification of novel candidate genes for age at first calving in Nellore cows using a SNP chip specifically developed for Bos taurus indicus cattle., PMID:34392169
The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy., PMID:34130600
For research use only. Not for human or drug use.
