Catalog No.
YHJ33001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro386-Pro488
Predicted molecular weight
13.79 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92769
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Histone deacetylase 2, HDAC2, HD2
TAp73α drives cancer metastasis via PPI-mediated derepression of the neuronal HDAC2/REST-GABBR2 axis., PMID:40505831
Histone Acetylation Modifications and HDACs are Associated with Resilience or Susceptibility to Stress in a Rat Model of Major Depressive Disorder., PMID:40504297
VPA Enhances Pulp Regeneration by Regulating LPS-Induced Human Dental Pulp Stem Cells Odontogenic Differentiation., PMID:40494210
The epigenetic reader PHF23 is required for embryonic neurogenesis., PMID:40447447
Photobiomodulation therapy: Location-dependent effects on memory and recovery in male adult rats with spinal cord injury., PMID:40447286
Kirenol alleviates cerebral ischemic injury by promoting synaptic plasticity via HDAC2-mediated BDNF expression., PMID:40446576
Genomic analyses identify 15 risk loci and reveal HDAC2, SOX2-OT, and IGF2BP2 in a naturally occurring canine model of gastric cancer., PMID:40445765
NUDT21 lactylation reprograms alternative polyadenylation to promote cuproptosis resistance., PMID:40425546
The impact of mechanical unloading on the gut microbiota and the mitigating role of butyrate in bone loss., PMID:40424649
Porphyromonas gingivalis aggravates atherosclerotic plaque instability by promoting lipid-laden macrophage necroptosis., PMID:40404630
Renometabolic disorder in experimental rat model of polycystic ovarian syndrome is reversed by acetate-mediated inhibition of pyruvate dehydrogenase kinase 4., PMID:40361039
Tie2 activity in cancer associated myofibroblasts serves as novel target against reprogramming of cancer cells to embryonic-like cell state and associated poor prognosis in oral carcinoma patients., PMID:40349056
LINC00908 Inactivates Wnt/β-Catenin Signaling Pathway to Inhibit Prostate Cancer Cell Stemness via Upregulating GSK3B and FBXW2., PMID:40344383
The Mechanism of HDAC2 Inhibitors on Chronic Pancreatitis Pain., PMID:40337468
Down-regulating HDAC2-LTA4H pathway ameliorates renal ischemia-reperfusion injury., PMID:40324735
Transcriptome associated with single-cell analysis reveal the role of S-palmitoylation in coronary artery disease., PMID:40307438
Design and synthesis of pyridine-based benzamides as potent HDAC3 inhibitors as an armament against breast cancer with in vivo validation., PMID:40267875
Butyrate inhibits histone deacetylase 2 expression to alleviate liver fibrosis in biliary atresia., PMID:40221650
HDAC1 acts as a tumor suppressor in ALK-positive anaplastic large cell lymphoma: implications for HDAC inhibitor therapy., PMID:40175628
Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment., PMID:40175372
Suppression of adipose TGF-β1 by probiotics alleviates metabolic disturbance in experimentally induced PCOS., PMID:40154941
New uses of halofuginone to treat cancer., PMID:40099206
Trichostatin A-Induced Epigenetic Modifications and Their Influence on the Development of Porcine Cloned Embryos Derived from Bone Marrow-Mesenchymal Stem Cells., PMID:40076980
TET2 suppresses vascular calcification by forming an inhibitory complex with HDAC1/2 and SNIP1 independent of demethylation., PMID:40067382
Competitive antagonism of KAT7 crotonylation against acetylation affects procentriole formation and colorectal tumorigenesis., PMID:40064919
Molecular mechanism behind the cholinium-taurate ionic liquid in stabilisation of HDAC2 for alcohol use disorders: insights from DFT and MD simulations., PMID:40062365
Triple regulation of oxidative-acetylation cycling pathways in COPD glucocorticoid resistance by HuaTanJiangQi capsules., PMID:40060290
HAT1/HDAC2 mediated ACSL4 acetylation confers radiosensitivity by inducing ferroptosis in nasopharyngeal carcinoma., PMID:40050614
Discovery and evaluation of novel Benzohydroxamic acid-indole derivatives as dual inhibitors of ADAM17 and HDAC2 with antitumor activity., PMID:40049049
Lysine 2-hydroxyisobutyrylation of HXK1 alters energy metabolism and KATP channel function in the atrium from patients with atrial fibrillation., PMID:40033384
Utility of a Large Series of B-Cell Precursor Acute Lymphoblastic Leukemia Cell Lines as a Model System., PMID:40022573
HBV-associated hepatocellular carcinomas inhibit antitumor CD8+ T cell via the long noncoding RNA HDAC2-AS2., PMID:40021665
Rhynchophylline alleviates cognitive deficits in multiple transgenic mouse models of Alzheimer's disease via modulating neuropathology and gut microbiota., PMID:40011632
Exploring the role of glucocorticoid receptors and co-chaperones in Pemphigus foliaceus stratification., PMID:39988616
HDAC2-Mediated METTL3 Delactylation Promotes DNA Damage Repair and Chemotherapy Resistance in Triple-Negative Breast Cancer., PMID:39950833
Comprehensive transcriptomics analysis of peripheral blood mononuclear cells in exposure to mustard gas., PMID:39946765
Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations., PMID:39939763
UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors., PMID:39939761
Myricetin Mitigated Sevoflurane-induced Cognitive Dysfunction in Aged-mice Through Inhibiting Histone Deacetylase 2/nuclear Factor Erythroid 2-related Factor 2/heme Oxygenase-1 Signalling-mediated Ferroptosis and Mitochondrial Dysfunction., PMID:39937417
PJA2 Suppresses Colorectal Cancer Progression by Controlling HDAC2 Degradation and Stability., PMID:39928532
IFI16 recruits HDAC1 and HDAC2 to deacetylate the Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA), facilitating latency., PMID:39927772
Construction and Validation of a Novel Butyrylation-Related Gene Signature Related to Prognosis, Clinical Implications, and Immune Microenvironment Characterization of Hepatocellular Carcinoma., PMID:39926543
Chemoproteomics Sheds Light on Epigenetic Targets of [11C]Martinostat in the Human Brain., PMID:39912892
Discovery of novel biphenyl compounds bearing hydroxamic acid moiety as the first PD-L1/class I HDACs dual inhibitors., PMID:39912413
Vitamin D Receptor rs2228570 Gene Polymorphism Is Associated with Asthma Severity and Exacerbations., PMID:39894560
Anticancer activity of Ilex khasiana, a rare and endemic species of holly in Northeast India, against murine lymphoma., PMID:39885875
HDAC2 promotes colorectal tumorigenesis by triggering dysregulation of lipid metabolism through YAP1., PMID:39875048
Down-regulation of histone deacetylase 2 attenuates ventricular arrhythmias in a mouse model of cardiac hypertrophy through up-regulation of Kv channel-interacting protein 2 expression., PMID:39870585
Effects of treadmill running on anxiety- and craniofacial pain-like behaviors with histone H3 acetylation in the brain of mice subjected to social defeat stress., PMID:39869606
HDAC1 and HDAC2 Are Involved in Influenza A Virus-Induced Nuclear Translocation of Ectopically Expressed STAT3-GFP., PMID:39861822
For research use only. Not for human or drug use.
