Catalog No.
YHJ31301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln25-Asp227
Predicted molecular weight
24.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92520
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interleukin-like EMT inducer, FAM3C, ILEI, Protein FAM3C
Stage-dependent proteomic alterations in aqueous humor of diabetic retinopathy patients based on data-independent acquisition and parallel reaction monitoring., PMID:40281624
Impact of DNA methylation on digestive and metabolic gene expression in red pandas (Ailurus fulgens) during the transition from milk to bamboo diet., PMID:40275147
FAM3C Regulates Glioma Cell Proliferation, Invasion, Apoptosis, and Epithelial Mesenchymal Transition via the Notch Pathway., PMID:39629744
Potential molecular mechanisms of ETV6-RUNX1-positive B progenitor cell cluster in acute lymphoblastic leukemia revealed by single-cell RNA sequencing., PMID:39498293
Quantitative proteomics combined independent PRM analysis reveals the mitochondrial and synaptic mechanism underlying norisoboldine's antidepressant effects., PMID:39358323
Genetic variants associated with white blood cell count amongst individuals with sickle cell disease., PMID:39279196
Network-Based Transcriptome Analysis Reveals FAM3C as a Novel Potential Biomarker for Glioblastoma., PMID:38923575
Ganoderic acid A ameliorates depressive-like behaviors in CSDS mice: Insights from proteomic profiling and molecular mechanisms., PMID:38723681
Targeting the High-Density Lipoprotein Proteome for the Treatment of Post-Acute Sequelae of SARS-CoV-2., PMID:38674105
Reduction of Amyloid-β Production without Inhibiting Secretase Activity by MS-275., PMID:38416107
H3K27ac-activated LncRNA NUTM2A-AS1 Facilitated the Progression of Colorectal Cancer Cells via MicroRNA-126-5p/FAM3C Axis., PMID:38347779
FAM3C in Cancer-Associated Adipocytes Promotes Breast Cancer Cell Survival and Metastasis., PMID:38117489
SOX2 promotes a cancer stem cell-like phenotype and local spreading in oral squamous cell carcinoma., PMID:38096163
PCBP1 regulates LIFR through FAM3C to maintain breast cancer stem cell self-renewal and invasiveness., PMID:37927213
Relative Abundance of Spermadhesin-1 in the Seminal Plasma of Young Nellore Bulls Is in Agreement with Reproductive Parameters., PMID:37888562
FAM3 family genes are associated with prognostic value of human cancer: a pan-cancer analysis., PMID:37704682
A longitudinal genome-wide association study of bone mineral density mean and variability in the UK Biobank., PMID:37500982
Proteomic research on new urinary biomarkers of renal disease in canine leishmaniosis: Survival and monitoring response to treatment., PMID:37419051
FAM3C/ILEI protein is elevated in psoriatic lesions and triggers psoriasiform hyperproliferation in mice., PMID:37226685
Identification of Potential Indicators for Survival in Patients with Thyroid Cancer Based on Expression of FAM3 Members., PMID:37183945
Structural analysis of factors related to FAM3C/ILEI dimerization and identification of inhibitor candidates targeting cancer treatment., PMID:37068312
Neutrophils promote tumor invasion via FAM3C-mediated epithelial-to-mesenchymal transition in gastric cancer., PMID:37056931
Multiple Mechanisms Explain Genetic Effects at the CPED1-WNT16 Bone Mineral Density Locus., PMID:36943599
Human FAM3C restores memory-based thermotaxis of Caenorhabditis elegans famp-1/m70.4 loss-of-function mutants., PMID:36712359
Identification of immune- and autophagy-related genes and effective diagnostic biomarkers in endometriosis: a bioinformatics analysis., PMID:36660690
FAM3C in circulating tumor-derived extracellular vesicles promotes non-small cell lung cancer growth in secondary sites., PMID:36632230
Uncovering Novel Prognostic Factors of Sudden Sensorineural Hearing Loss by Whole-Genome Sequencing of Cell-Free DNA., PMID:36349665
Single-Cell Heterogeneity of the Liver-Infiltrating Lymphocytes in Individuals with Chronic Echinococcus multilocularis Infection., PMID:36317875
Identification of a novel prognostic signature correlated with epithelial-mesenchymal transition, N6-methyladenosine modification, and immune infiltration in colorectal cancer., PMID:36281556
Cardioprotective factors against myocardial infarction selected in vivo from an AAV secretome library., PMID:36044596
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway., PMID:35982901
CD44+ and CD133+ Non-Small Cell Lung Cancer Cells Exhibit DNA Damage Response Pathways and Dormant Polyploid Giant Cancer Cell Enrichment Relating to Their p53 Status., PMID:35563313
FAM3 Family as Prognostic Factors for Head and Neck Squamous Cell Carcinoma., PMID:35538834
Transcriptional downregulation of FAM3C/ILEI in the Alzheimer's brain., PMID:34378027
Multivariate Analysis Identifies Eight Novel Loci Associated with Meat Productivity Traits in Sheep., PMID:33806625
FAM3C: an emerging biomarker and potential therapeutic target for cancer., PMID:33666514
The FAM3C locus that encodes interleukin-like EMT inducer (ILEI) is frequently co-amplified in MET-amplified cancers and contributes to invasiveness., PMID:33596971
Extracellular Release of ILEI/FAM3C and Amyloid-β Is Associated with the Activation of Distinct Synapse Subpopulations., PMID:33492290
Genetic variants in the FAM3C gene are associated with lipid traits in Chinese children., PMID:32316026
miR-574-3p inhibits proliferation and invasion in esophageal cancer by targeting FAM3C and MAPK1., PMID:31880039
Genome-wide association study for backfat thickness at 100 kg and loin muscle thickness in domestic pigs based on genotyping by sequencing., PMID:31100035
FAM3C-YY1 axis is essential for TGFβ-promoted proliferation and migration of human breast cancer MDA-MB-231 cells via the activation of HSF1., PMID:30887707
TGFβ promotes breast cancer stem cell self-renewal through an ILEI/LIFR signaling axis., PMID:30692635
Overexpression of FAM3C is associated with poor prognosis in oral squamous cell carcinoma., PMID:30683473
Overexpression of FAM3C protein as a novel biomarker for epithelial-mesenchymal transition and poor outcome in gastric cancer., PMID:31949820
Common and rare variants of WNT16, DKK1 and SOST and their relationship with bone mineral density., PMID:30026596
High-fat diet disrupts bone remodeling by inducing local and systemic alterations., PMID:29986312
Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1)., PMID:29871931
ILEI is an important intermediate participating in the formation of TGF-β1-induced renal tubular EMT., PMID:29336056
FAM3C activates HSF1 to suppress hepatic gluconeogenesis and attenuate hyperglycemia of type 1 diabetic mice., PMID:29285313
For research use only. Not for human or drug use.
