Catalog No.
YHJ31001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met13360-Gln14347
Predicted molecular weight
111.97 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8WXI7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mucin-16, CA-125, Ovarian carcinoma antigen CA125, CA125, MUC-16, Ovarian cancer-related tumor marker CA125, MUC16
Genomic and physiological characteristics for survival in melanoma: a genetic epidemiology study., PMID:40506001
Deciphering Deleterious nsSNPs in MUC16's SEA Domain: Structural and Functional Implications in Cancer Metastasis via Computational Analysis., PMID:40478193
Identification and Validation of Key Genes Involved in the Coupling of Mitochondria-Associated Endoplasmic Reticulum Membrane in Hemorrhoidal Disease., PMID:40469970
Synergistic Signal Amplification via Weak Value Amplification Effect and Sandwich Structure for Highly Sensitive and Specific Real-Time Detection of CA125., PMID:40422007
Mutational and Expressional Similarities Among Paraganglioma, Low-Grade Glioma, and Glioblastoma: A Comprehensive Clustering Approach to Central Nervous System Tumors., PMID:40420762
The prognostic role of omental, ovarian chemotherapy response score and CA125 in predicting survival in patients with tubo-ovarian high-grade serous carcinoma/primary peritoneal carcinoma receiving neoadjuvant chemotherapy., PMID:40377601
Interface self-shelling effect-mediated photoinduced carrier transport and multiplexed signal amplification mechanism in self-powered photoelectrochemical biosensing., PMID:40367664
CA125 Serum Levels in BRCA1/BRCA2 Pathogenic Sequence Variant Carriers as an Ovarian Cancer Screening Tool: A Longitudinal Study., PMID:40365969
Mapping the Binding Sites of CA125-Specific Antibodies on a Revised Molecular Model of MUC16., PMID:40361385
The role of maternal age, markers of ultrasound, sFlt-1 and CA125 serum levels in the prediction of miscarriage: Study acronym: MIS-CARE (markers of ultrasound, immunologic and serum factors in the comprehensive analysis of the risks for early pregnancy loss)., PMID:40345104
Rebamipide Enhances Pathogen Defense and Mitigates Inflammation in a Particulate Matter-Induced Ocular Surface Inflammation Rat Model., PMID:40332777
Restricted cubic spline analysis: Age-dependent relationship between MAGEA12 and hepatocellular carcinoma prognosis., PMID:40317152
The Role of Antigen Carbohydrate 125 in Modulating Soluble ST2: Prognostic-Related Effects in Acute Heart Failure., PMID:40305342
Clinical significance of human epididymis protein 4 (HE4), cancer antigen 125 (CA125), the risk of ovarian malignancy algorithm (ROMA), and Copenhagen index (CPH-I) for the diagnosis of endometrial carcinoma., PMID:40270170
Characteristics, clinical findings, and treatment of idiopathic pulmonary fibrosis in Japanese patients registered with a medical subsidy system for intractable diseases., PMID:40250140
A Prospective Study Consortium for the Discovery and Validation of Early Detection Markers for Ovarian Cancer - Baseline Findings for CA125., PMID:40227208
The combination of CA125, CA199, CEA, and AFP is an effective diagnostic biomarker for gastric cancer in elderly individuals., PMID:40221735
Integrating genomic features for prognosis in Chinese patients with B-cell lymphoma following chimeric antigen receptor T-cell therapy., PMID:40189492
External validation of CEA and CA125 prediction model for lymph node metastasis in endometrial cancer: A multi-institute cohort study., PMID:40183305
Serum CA125: a prognostic biomarker for mortality in chronic heart failure., PMID:40148772
Systematic comprehension of genomics and mutational landscape of glioma: A goal towards advanced therapeutics., PMID:40127758
A bispecific anti-MUC16/anti-death receptor 5 antibody achieves effective and tumor-selective death receptor 5-mediated tumor regression., PMID:40121208
A perspective on the potential use of aptamer-based field-effect transistor sensors as biosensors for ovarian cancer biomarkers CA125 and HE4., PMID:40120511
Myeloid targeting antibodies PY159 and PY314 for platinum-resistant ovarian cancer., PMID:40081941
Integrated Analysis of WES and scRNA-Seq Data Reveals the Genetic Basis of Immune Dysregulation in Unexplained Recurrent Pregnancy Loss., PMID:40066928
High-Efficiency Cell-Type Proteomics Strategy Deciphers Cholangiocarcinoma Fibrosis-Associated Pathological Heterogeneity., PMID:40033664
Prospective external validation and exploration of the "2021 AAGL endometriosis classification"., PMID:40020456
The role of MUC16 in tumor biology and tumor immunology in ovarian cancer., PMID:39972413
Ti3C2/Fe3O4 - based surface plasmon resonance imaging biosensor for efficient separation and sensitive detection of CA125 in serum., PMID:39960621
Integrative bioinformatic analysis of prognostic biomarkers in heart failure: Insights from clinical trials., PMID:39957002
Overlap of Genomic and Transcriptomic Genes Identified in Familial Eosinophilic Esophagitis., PMID:39914776
Immune checkpoint expression and therapeutic implications in IDH1-mutant and wild-type glioblastomas., PMID:39864140
MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer., PMID:39863644
CA-125 as a Biomarker in Renal Medullary Carcinoma: Integrated Molecular Profiling, Functional Characterization, and Prospective Clinical Validation., PMID:39836407
An "on-off" electrochemical immunosensor for the detection of the glycan antigen CA125 by amplification signals using electropositive COFs., PMID:39813914
The modulating effect of circulating carbohydrate antigen 125 on ST2 and long-term recurrent morbidity burden., PMID:39809935
Multicenter study of ovarian cancer score for diagnosing ovarian cancer., PMID:39793443
An electrochemical immunosensor for carbohydrate antigen CA125 based on electroactive COFs as a signal probe., PMID:39778493
Serum CA125 levels in the context of ProMisE molecular classification provides pre-operative prognostic information that can direct endometrial cancer management., PMID:39740305
Excess shed mesothelin disrupts pancreatic cancer cell clustering to impair peritoneal colonization., PMID:39673668
Translational findings support regimen selection for first-in-human study of ubamatamab (MUC16 × CD3 bispecific antibody) in patients with recurrent ovarian cancer., PMID:39652449
Holliday junction recognition protein (HJURP) could reflect the clinical outcomes of lung adenocarcinoma patients, and impact the choice of precision therapy., PMID:39649097
Value of miR200b and its combination with other biochemical markers in the diagnosis of epithelial ovarian cancer., PMID:39638936
Pretargeted alpha therapy in MUC16-positive high-grade serous ovarian cancer., PMID:39615062
Unraveling O-Glycan Diversity of Mucins: Insights from SmE Mucinase and Ultraviolet Photodissociation Mass Spectrometry., PMID:39576755
LRP1B associated with immune cell infiltration influenced the efficacy of immunotherapy in colorectal cancer patients., PMID:39532036
Breast cancer genomic analyses reveal genes, mutations, and signaling networks., PMID:39496981
Putative mechanisms of primary resistance to EGFR-targeted therapies: A retrospective study., PMID:39490204
Risk-stratified CA125 screening integrating CA125 trajectories, trajectory-specific progression and transvaginal ultrasound for ovarian cancer., PMID:39462415
MUC16 Retention after Neoadjuvant Chemotherapy in Pancreatic Ductal Adenocarcinoma., PMID:39456534
For research use only. Not for human or drug use.
