Catalog No.
YHJ26901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys453
Predicted molecular weight
53.78 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8NI77
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KIF18A, Marrow stromal KIF18A, Kinesin-like protein KIF18A, MS-KIF18A
Integrated Profiling Delineated KIF18A as a Significant Biomarker Associated with Both Prognostic Outcomes and Immune Response in Pancreatic Cancer., PMID:40040635
Kinesin-like protein KIF18A is required for faithful coordination of chromosome congression with cytokinesis., PMID:39954259
KIF18A Is a Novel Target of JNK1/c-Jun Signaling Pathway Involved in Cervical Tumorigenesis., PMID:39749722
Targeting chromosomally unstable tumors with a selective KIF18A inhibitor., PMID:39747049
HPV16 entry requires dynein for minus-end transport and utilizes kinesin Kif11 for plus-end transport along microtubules during mitosis., PMID:39629998
Chromosome alignment and Kif18A action rely on spindle-localized control of Cdk1 activity., PMID:39610707
KIF18A inhibition: the next big player in the search for cancer therapeutics., PMID:39580563
Microtubule poleward flux as a target for modifying chromosome segregation errors., PMID:39541344
HURP regulates Kif18A recruitment and activity to synergistically control microtubule dynamics., PMID:39516196
Maternal genetic variants in kinesin motor domains prematurely increase egg aneuploidy., PMID:39475646
[Bipolar Action of Inhibitor of Vasculogenic Mimicry on Gene Expression in Melanoma Cells]., PMID:39355886
KIF18A promotes cervical squamous cell carcinoma progression by activating the PI3K/AKT pathway through upregulation of CENPE., PMID:39331093
Mechanisms of minor pole-mediated spindle bipolarization in human oocytes., PMID:39172836
Exploration of inhibitors targeting KIF18A with ploidy-specific lethality., PMID:39168405
Maternal genetic variants in kinesin motor domains prematurely increase egg aneuploidy., PMID:39006445
Suppressing Anaphase-Promoting Complex/Cyclosome-Cell Division Cycle 20 Activity to Enhance the Effectiveness of Anti-Cancer Drugs That Induce Multipolar Mitotic Spindles., PMID:38928036
Molecular interplay between HURP and Kif18A in mitotic spindle regulation., PMID:38854046
Molecular interplay between HURP and Kif18A in mitotic spindle regulation., PMID:38645125
Chromatin activation with H3K36me2 and compartment shift in metastatic castration-resistant prostate cancer., PMID:38490329
Kinesin Family Member-18A (KIF18A) Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma., PMID:38446308
Identification of the KIF18A alpha-4 helix as a therapeutic target for chromosomally unstable tumor cells., PMID:38410188
KIF18A inactivates hepatic stellate cells and alleviates liver fibrosis through the TTC3/Akt/mTOR pathway., PMID:38372748
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition., PMID:38279026
Therapeutic targeting of the KIF18A motor protein in cancers with chromosomal instability., PMID:38267629
Impact of immunohistochemical expression of kinesin family member 18A (Kif18A) and β-catenin in infiltrating breast carcinoma of no special type., PMID:38195458
Neocortical neurogenesis in development and evolution-Human-specific features., PMID:38189676
Genome-wide DNA methylation of lesional and peri-lesional skin in vitiligo: a comparative and integrated analysis of multi-omics in Chinese population., PMID:38182908
Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers., PMID:38151625
Identification of the KIF18A alpha-4 helix as a therapeutic target for chromosomally unstable tumor cells., PMID:37905069
Modification of the neck-linker of KIF18A alters Microtubule subpopulation preference., PMID:37903223
KIF18A improves migration and invasion of colorectal cancer (CRC) cells through inhibiting PTEN signaling., PMID:37708299
Genetic enhancers of partial PLK1 inhibition reveal hypersensitivity to kinetochore perturbations., PMID:37639469
Resistance to vincristine in DLBCL by disruption of p53-induced cell cycle arrest and apoptosis mediated by KIF18B and USP28., PMID:37190875
Microtubule depolymerization contributes to spontaneous neurotransmitter release in vitro., PMID:37147475
KIF18A interacts with PPP1CA to promote the malignant development of glioblastoma., PMID:36911368
Comprehensive Pan-Cancer Analysis of KIF18A as a Marker for Prognosis and Immunity., PMID:36830695
BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms., PMID:36550359
Comprehensive analysis of a TPX2-related TRHDE-AS1/PKIA ceRNA network involving prognostic signatures in Hepatitis B virus-infected hepatocellular carcinoma., PMID:36204642
A 9-gene prognostic signature for kidney renal clear cell carcinoma overall survival based on co-expression and regression analyses., PMID:36053927
Length-dependent poleward flux of sister kinetochore fibers promotes chromosome alignment., PMID:35926461
Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development., PMID:35905187
Recurrence- and Malignant Progression-Associated Biomarkers in Low-Grade Gliomas and Their Roles in Immunotherapy., PMID:35677036
Prognostic Biomarker KIF18A and Its Correlations With Immune Infiltrates and Mitosis in Glioma., PMID:35591854
The chirality of the mitotic spindle provides a mechanical response to forces and depends on microtubule motors and augmin., PMID:35537456
The Proliferation of Glioblastoma Is Contributed to Kinesin Family Member 18A and Medical Data Analysis of GBM., PMID:35464837
Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical Probe., PMID:35286090
A novel HDAC11 inhibitor potentiates the tumoricidal effects of cordycepin against malignant peripheral nerve sheath tumor through the Hippo signaling pathway., PMID:35261809
Integrated bioinformatics analysis to identify key genes related to the prognosis of esophageal squamous cell carcinoma., PMID:35116493
Role of Hub Genes in the Occurrence and Development of Testicular Cancer Based on Bioinformatics., PMID:35082515
Bioinformatics Analysis Using ATAC-seq and RNA-seq for the Identification of 15 Gene Signatures Associated With the Prediction of Prognosis in Hepatocellular Carcinoma., PMID:34760691
For research use only. Not for human or drug use.
