Catalog No.
DHE51802
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG4-kappa
Clonality
Monoclonal
Target
GCGR, Glucagon receptor, GL-R
Concentration
2.55 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P47871
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
REGN-1193, CAS: 1452387-69-7
Clone ID
Crotedumab
Glucagon receptor as a drug target: A witches' brew of eye of newt (peptides) and toe of frog (receptors), PMID: 28842950
A first-in-human pharmacodynamic and pharmacokinetic study of a fully human anti-glucagon receptor monoclonal antibody in normal healthy volunteers, PMID: 28755409
Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys, PMID: 26020795
Glucagon receptor as a drug target: A witches' brew of eye of newt (peptides) and toe of frog (receptors)., PMID:28842950
A first-in-human pharmacodynamic and pharmacokinetic study of a fully human anti-glucagon receptor monoclonal antibody in normal healthy volunteers., PMID:28755409
Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys., PMID:26020795
For research use only. Not for human or drug use.
