Catalog No.
YHJ23401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn257-Asn477
Predicted molecular weight
27.22 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8NAC3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IL-17RC, IL-17RL, ZcytoR14, Interleukin-17 receptor C, Interleukin-17 receptor homolog, IL17Rhom, IL17RC, IL-17 receptor C, Interleukin-17 receptor-like protein
Evolutionary insights and poly(I:C)-induced changes in expression and m6A modifications of il17ra and il17rc in Miichthysmiiuy., PMID:40239933
Brain-wide mapping of immune receptors uncovers a neuromodulatory role of IL-17E and the receptor IL-17RB., PMID:40199322
Analysis of Striped Bass (Morone saxatilis) and White Bass (M. chrysops) Splenic Transcriptome Following Streptococcus iniae Infection., PMID:39961922
Deciphering the role of IL17RA in psoriasis and chronic mucocutaneous candidiasis: shared pathways and distinct manifestations., PMID:39911581
Interleukin 17 RA and RC gene polymorphisms and increased preeclampsia risk: Single and combined genetic analysis., PMID:39908641
Rhythmic IL-17 production by γδ T cells maintains adipose de novo lipogenesis., PMID:39478228
Combination therapy of systemic and local metformin improves imiquimod-induced psoriasis-like lesions with type 2 diabetes: the role of AMPK/KGF/STAT3 axis., PMID:39446079
Altered expression pattern of immune response-related genes and isoforms in hypersensitivity pneumonitis lung fibroblasts., PMID:39402115
Protein biomarker signatures of preeclampsia - a longitudinal 5000-multiplex proteomics study., PMID:39390022
Rare Genetic Variants of NLRP12 in Admixed Latino-American Children With SARS-CoV-2-Related Multisystem Inflammatory Syndrome., PMID:39328079
Genetic polymorphisms to identify patients with an optimal response to tildrakizumab in psoriasis patients from real-life clinical practice., PMID:39081053
[IL-17A and IL-17F: from discovery to target of biologics - an illustrative example of translational research]., PMID:39007775
Identification and functional characterization of fish IL-17 receptors suggest important roles in the response to nodavirus infection., PMID:38827125
Interleukin 17F Gene Polymorphism as a Potential Protective Factor in the Immunopathology of Ocular Toxoplasmosis., PMID:38767154
LECs regulate neutrophil clearance through IL-17RC/CMTM4/NF-κB axis at sites of inflammation or infection., PMID:38754839
Reciprocal crosstalk between Th17 and mesothelial cells promotes metastasis-associated adhesion of ovarian cancer cells., PMID:38566518
Association of interleukin-17A and chemokine/vascular endothelial growth factor-induced angiogenesis in newly diagnosed patients with bladder cancer., PMID:38515019
IL-17-producing cells in ankylosing spondylitis patients show gender-based differences in gene expression., PMID:38436300
Isolated Chronic Mucocutaneous Candidiasis due to a Novel Duplication Variant of IL17RC., PMID:38129603
Identification of cytokine-induced cell communications by pan-cancer meta-analysis., PMID:38054018
Innate Error Immunities of the Th17 Immune Pathway Associated With Chronic Mucocutaneous Candidiasis: A Systematic Review., PMID:38051840
Interleukin-17 and inflammatory bowel disease: a 2-sample Mendelian randomization study., PMID:38045694
Biomass-related PM2.5 induced inflammatory microenvironment via IL-17F/IL-17RC axis., PMID:38036089
IL-17 receptor A functions to help maintain barrier integrity and limit activation of immunopathogenic response to H. pylori infection., PMID:38014948
Differential effects of interleukin-17A and 17F on cell interactions between immune cells and stromal cells from synovium or skin., PMID:37932356
Interleukin-17 signaling influences CD8+ T cell immunity and tumor progression according to the IL-17 receptor subunit expression pattern in cancer cells., PMID:37808403
IL-17A inhibitor-induced leucocytoclastic vasculitis is responsive to IL-23 blockade in a psoriatic arthritis patient., PMID:37679036
Interaction of Interleukin-17A with a Th2 Response in a Mouse Model of Allergic Airway Inflammation., PMID:37443808
Chronic mucocutaneous candidiasis presenting as refractory fissured tongue in a patient with IL-17RC mutation: the first reported case of Chinese ethnicity., PMID:37395078
Interleukin-17 receptor C is essential for the pro-inflammatory pathogenicity of granulocyte-macrophage-colony-stimulating factor-producing T helper cells in experimental autoimmune uveitis., PMID:37336144
SARS-CoV-2 ORF8 Mediates Signals in Macrophages and Monocytes through MyD88 Independently of the IL-17 Receptor., PMID:37265402
Gene Expression Changes in Cytokine and Chemokine Receptors in Association with Melanoma Liver Metastasis., PMID:37240247
RUPP Th17s cause hypertension and mitochondrial dysfunction in the kidney and placenta during pregnancy., PMID:37104924
Interleukin-17A knockout or self-recovery alleviated autoimmune reaction induced by fluoride in mouse testis., PMID:37086998
IL-17A expression by both T cells and non-T cells contribute to HSV-IL-2-induced CNS demyelination., PMID:36817487
Associations of IL-17 and IL-17 receptor polymorphisms with Behçet's disease in Denizli Province of Turkey., PMID:36701075
Integrated multi-omics reveals novel microbe-host lipid metabolism and immune interactions in the donkey hindgut., PMID:36466834
Low-Dose IL-2 Attenuated Depression-like Behaviors and Pathological Changes through Restoring the Balances between IL-6 and TGF-β and between Th17 and Treg in a Chronic Stress-Induced Mouse Model of Depression., PMID:36430328
IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling., PMID:36260993
IL-17A promotes Helicobacter pylori-induced gastric carcinogenesis via interactions with IL-17RC., PMID:36125689
Synoviocytes and skin fibroblasts show opposite effects on IL-23 production and IL-23 receptor expression during cell interactions with immune cells., PMID:36088336
Main human inborn errors of immunity leading to fungal infections., PMID:35863627
MEFV, IRF8, ADA, PEPD, and NBAS gene variants and elevated serum cytokines in a patient with unilateral sporadic Meniere's disease and vascular congestion over the endolymphatic sac., PMID:35847575
Interleukin-17 governs hypoxic adaptation of injured epithelium., PMID:35709248
Cross-tissue single-cell transcriptomic landscape reveals the key cell subtypes and their potential roles in the nutrient absorption and metabolism in dairy cattle., PMID:35499046
Predictive value of single-nucleotide polymorphisms in curve progression of adolescent idiopathic scoliosis., PMID:35434775
Impact of Adalimumab Treatment on Interleukin-17 and Interleukin-17 Receptor Expression in Skin and Synovium of Psoriatic Arthritis Patients with Mild Psoriasis., PMID:35203534
IL-17 Receptor C Signaling Controls CD4+ TH17 Immune Responses and Tissue Injury in Immune-Mediated Kidney Diseases., PMID:35167487
Expression and activity of IL-17 receptor subunits in human cutaneous cells as targets for anti-IL-17 therapeutic antibodies., PMID:35062060
Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation., PMID:35004653
For research use only. Not for human or drug use.
