Catalog No.
YHJ22001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu49-Asn242
Predicted molecular weight
24.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8N4E7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ferritin, mitochondrial, FTMT
Stimulation of Soluble Guanylyl Cyclase (sGC) by Cinaciguat Attenuates Sepsisinduced Cardiac Injury., PMID:40396316
Human mitochondrial ferritin exhibits highly unusual iron-O2 chemistry distinct from that of cytosolic ferritins., PMID:40393986
Mitochondrial ferritin inhibition aggravates pacing-induced ventricular arrhythmias after myocardial infarction by promoting cardiomyocyte ferroptosis., PMID:40023300
Bidirectional Mendelian Randomization identifies plasma proteins associated with urticaria risk., PMID:39961865
Mendelian randomization analysis of plasma proteins reveals potential novel tumor markers for gastric cancer., PMID:39875498
Angiotensin type 1 and type 2 receptors-induced mitochondrial dysfunction promotes ferroptosis in cardiomyocytes., PMID:39789125
Mitochondrial ferritin upregulation by deferiprone reduced neuronal ferroptosis and improved neurological deficits via NDRG1/Yap pathway in a neonatal rat model of germinal matrix hemorrhage., PMID:39318194
[Mechanism of ligustilide in attenuating OGD/R-induced HT22 cell injury based on FtMt inhibition of ferroptosis]., PMID:39307749
Transcriptome and proteomic analysis reveal the protective mechanism of acupuncture on reproductive function in mice with asthenospermia., PMID:39286182
FTMT-dependent mitophagy is crucial for ferroptosis resistance in cardiac fibroblast., PMID:39168410
Iron accumulation in ovarian microenvironment damages the local redox balance and oocyte quality in aging mice., PMID:38781731
Luteolin attenuates CCl4-induced hepatic injury by inhibiting ferroptosis via SLC7A11., PMID:38755566
Mitochondrial ferritin alleviates ferroptosis in a kainic acid-induced mouse epilepsy model by regulating iron homeostasis: Involvement of nuclear factor erythroid 2-related factor 2., PMID:38439636
Cold-inducible RNA binding protein alleviates iron overload-induced neural ferroptosis under perinatal hypoxia insult., PMID:38388728
Mitochondrial ferritin upregulation reduced oxidative stress and blood-brain-barrier disruption by maintaining cellular iron homeostasis in a neonatal rat model of germinal matrix hemorrhage., PMID:38281588
Newly uncovered biochemical and functional aspects of ferritin., PMID:37440196
Immunohistochemical Analysis of Mitochondrial Ferritin in the Midbrain of Patients with Parkinson's Disease., PMID:37124956
FtMt reduces oxidative stress-induced trophoblast cell dysfunction via the HIF-1α/VEGF signaling pathway., PMID:36859279
A genome-wide association study identifies a novel association between SDC3 and apparent treatment-resistant hypertension., PMID:36447229
Mitochondrial ferritin expression in human macrophages is facilitated by thrombin-mediated cleavage under hypoxia., PMID:36416578
The Ferroptosis Inhibitor Liproxstatin-1 Ameliorates LPS-Induced Cognitive Impairment in Mice., PMID:36364859
Mitochondrial ferritin alleviates apoptosis by enhancing mitochondrial bioenergetics and stimulating glucose metabolism in cerebral ischemia reperfusion., PMID:36179435
Expression of Iron Metabolism Proteins in Patients with Chronic Heart Failure., PMID:35160288
LC3/FtMt Colocalization Patterns Reveal the Progression of FtMt Accumulation in Nigral Neurons of Patients with Progressive Supranuclear Palsy., PMID:35008961
PURA-Related Developmental and Epileptic Encephalopathy: Phenotypic and Genotypic Spectrum., PMID:34790866
The multifaceted regulation of mitophagy by endogenous metabolites., PMID:34583624
Immunohistochemical Study of Mitochondrial Ferritin in the Midbrain of Patients with Progressive Supranuclear Palsy., PMID:34276103
Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis., PMID:33953171
Mitochondrial Ferritin Deficiency Promotes Osteoblastic Ferroptosis Via Mitophagy in Type 2 Diabetic Osteoporosis., PMID:33594527
Iron loss triggers mitophagy through induction of mitochondrial ferritin., PMID:32975364
FtMt promotes glioma tumorigenesis and angiogenesis via lncRNA SNHG1/miR-9-5p axis., PMID:32858123
Hypoxia inhibits ferritinophagy, increases mitochondrial ferritin, and protects from ferroptosis., PMID:32810738
Effects of FTMT Expression by Retinal Pigment Epithelial Cells on Features of Angiogenesis., PMID:32455741
A Variation in FGF14 Is Associated with Downbeat Nystagmus in a Genome-Wide Association Study., PMID:32157568
A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia., PMID:31882562
Biallelic variants in LARS2 and KARS cause deafness and (ovario)leukodystrophy., PMID:30737337
Differences in Gene Expression Profiles and Phenotypes of Differentiated SH-SY5Y Neurons Stably Overexpressing Mitochondrial Ferritin., PMID:30670947
Synthesis of 5-Hydroxy-3',4',7-trimethoxyflavone and Related Compounds and Elucidation of Their Reversal Effects on BCRP/ABCG2-Mediated Anticancer Drug Resistance., PMID:30187992
Roflumilast enhances cisplatin-sensitivity and reverses cisplatin-resistance of ovarian cancer cells via cAMP/PKA/CREB-FtMt signalling axis., PMID:30069985
Mitochondrial ferritin expression in erythroid cells from patients with alpha-thalassaemia., PMID:29993346
Mitochondrial Ferritin Is a Hypoxia-Inducible Factor 1α-Inducible Gene That Protects from Hypoxia-Induced Cell Death in Brain., PMID:29402144
Lack of mitochondrial ferritin aggravated neurological deficits via enhancing oxidative stress in a traumatic brain injury murine model., PMID:28963372
Mitochondrial Ferritin Protects Hydrogen Peroxide-Induced Neuronal Cell Damage., PMID:28840060
The Construction and Characterization of Mitochondrial Ferritin Overexpressing Mice., PMID:28703745
Characterization of a Novel Monoclonal Antibody against Human Mitochondrial Ferritin and Its Immunohistochemical Application in Human and Monkey Substantia Nigra., PMID:28386150
Mitochondrial Ferritin Deletion Exacerbates β-Amyloid-Induced Neurotoxicity in Mice., PMID:28191272
Impact of TET2 deficiency on iron metabolism in erythroblasts., PMID:28167288
Mitochondrial ferritin protects SH-SY5Y cells against H2O2-induced oxidative stress and modulates α-synuclein expression., PMID:28163159
The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis., PMID:28066232
Mitochondrial ferritin deficiency reduces male fertility in mice., PMID:28063464
For research use only. Not for human or drug use.
