Catalog No.
YHJ21701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val168-Pro378
Predicted molecular weight
25.55 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8N441
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FGF homologous factor receptor, FGFR-like protein, Fibroblast growth factor receptor 5, Fibroblast growth factor receptor-like 1, FGF receptor-like protein 1, FGFRL1, FGFR-5, FHFR, FGFR5
Identifying therapeutic target genes for migraine by systematic druggable genome-wide Mendelian randomization., PMID:38867170
Pancreatic cancer stem cell-derived exosomal miR-210 mediates macrophage M2 polarization and promotes gemcitabine resistance by targeting FGFRL1., PMID:38134594
LncRNA VPS9D1-AS1 regulates miR-187-3p/fibroblast growth factor receptor-like 1 axis to promote proliferation, migration, and invasion of prostate cancer cells., PMID:37929340
Shared Genetics and Comorbid Genes of Amyotrophic Lateral Sclerosis and Parkinson's Disease., PMID:37534731
Presence of PD-1 similarity genes in monocytes may promote the development of type 1 diabetes mellitus and poor prognosis of pancreatic cancer., PMID:37130628
Aberrant Expression of FGFRL1 in Esophageal Cancer and Its Regulation by miR-107., PMID:37116156
Downregulation of miR-210-3p Attenuates High Glucose-Induced Angiogenesis of Vascular Endothelial Cells via Targeting FGFRL1., PMID:37062273
Transcriptome analyses reveal differentially expressed genes associated with development of the palatal organ in bighead carp (Hypophthalmichthys nobilis)., PMID:36990038
Genetic variants of FGFR family associated with height, hypertension, and osteoporosis., PMID:36876654
Distinct effects of SDC3 and FGFRL1 on selective neurodegeneration in AD and PD., PMID:36629784
HuR affects chemoresistance of small cell lung cancer by regulating FGFRL1 expression., PMID:36160905
FGFRL1 and FGF genes are associated with height, hypertension, and osteoporosis., PMID:35980984
[Overexpression of fibroblast growth factor receptor like 1 (FGFRL1) inhibits proliferation and migration of HCT116 human colon cancer cells, and promotes their apoptosis]., PMID:35365991
Comprehending fibroblast growth factor receptor like 1: Oncogene or tumor suppressor?, PMID:34689016
Epigenetic landscape in blood leukocytes following ketosis and weight loss induced by a very low calorie ketogenic diet (VLCKD) in patients with obesity., PMID:34139469
Genomic relevance of FGF14 and associated genes on the prognosis of pancreatic cancer., PMID:34061869
Genome reveals giraffe's recipe for standing tall., PMID:33737467
Combination of Ginsenosides Rb2 and Rg3 Promotes Angiogenic Phenotype of Human Endothelial Cells via PI3K/Akt and MAPK/ERK Pathways., PMID:33643049
Evidence that FGFRL1 contributes to congenital diaphragmatic hernia development in humans., PMID:33443296
[Expression of fibroblast growth factor receptor like 1 protein in oral squamous cell carcinoma and its influence on tumor cell proliferation and migration]., PMID:33085242
Dissecting the Interaction of FGF8 with Receptor FGFRL1., PMID:33019532
Lung CSC-derived exosomal miR-210-3p contributes to a pro-metastatic phenotype in lung cancer by targeting FGFRL1., PMID:32396269
Whole exome sequencing identifies multiple novel candidate genes in familial gastroschisis., PMID:32163230
Fibroblast growth factor receptor-like-1: a new therapeutic target and unfavorable prognostic indicator for rectal adenocarcinoma., PMID:32098557
FGFRL1 affects chemoresistance of small-cell lung cancer by modulating the PI3K/Akt pathway via ENO1., PMID:31957179
Functional domains of the FgfrL1 receptor., PMID:31923383
Long non-coding RNA FGD5-AS1 promotes non-small cell lung cancer cell proliferation through sponging hsa-miR-107 to up-regulate FGFRL1., PMID:31919528
The Genetic Basis of Scale-Loss Phenotype in the Rapid Radiation of Takifugu Fishes., PMID:31835491
The role of fibroblast growth factor receptor (FGFR) protein-tyrosine kinase inhibitors in the treatment of cancers including those of the urinary bladder., PMID:31770593
Gene-gene interactions and associations of six hypertension related single nucleotide polymorphisms with obesity risk in a Chinese children population., PMID:30217759
FGFRL1 deficiency reduces motility and tumorigenic potential of cells derived from oesophageal squamous cell carcinomas., PMID:29963148
FGFRL1 Promotes Ovarian Cancer Progression by Crosstalk with Hedgehog Signaling., PMID:29675438
Prenatal diagnosis of a 1.6-Mb 4p16.3 interstitial microdeletion encompassing FGFRL1 and TACC3 associated with bilateral cleft lip and palate of Wolf-Hirschhorn syndrome facial dysmorphism and short long bones., PMID:29241927
Role of fibroblast growth factor receptors (FGFR) and FGFR like-1 (FGFRL1) in mesenchymal stromal cell differentiation to osteoblasts and adipocytes., PMID:28923346
Evolution of the fusogenic activity of the receptor FGFRL1., PMID:28596102
Fibroblast growth factor receptors in breast cancer., PMID:28459213
DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patients., PMID:28211912
Receptor FGFRL1 acts as a tumor suppressor in nude mice when overexpressed in HEK 293 Tet-On cells., PMID:28101211
MicroRNA-210 promotes cancer angiogenesis by targeting fibroblast growth factor receptor-like 1 in hepatocellular carcinoma., PMID:27666683
Receptor FGFRL1 does not promote cell proliferation but induces cell adhesion., PMID:27220341
MicroRNA alteration and putative target genes in high-grade prostatic intraepithelial neoplasia and prostate cancer: STAT3 and ZEB1 are upregulated during prostate carcinogenesis., PMID:27017949
Glucose tolerance in obese men is associated with dysregulation of some angiogenesis-related gene expressions in subcutaneous adipose tissue., PMID:29537219
Differential mRNA expression profiling in ovarian endometriotic tissue with versus without leuprolide acetate treatment., PMID:26374406
Cell-cell fusion induced by the Ig3 domain of receptor FGFRL1 in CHO cells., PMID:26025674
Systematic transcriptome analysis reveals tumor-specific isoforms for ovarian cancer diagnosis and therapy., PMID:26015570
Divergent functions of fibroblast growth factor receptor-like 1 genes in grass carp (Ctenopharyngodon idella)., PMID:25981703
Identification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies., PMID:25941324
Phylogenetic analysis of receptor FgfrL1 shows divergence of the C-terminal end in rodents., PMID:25934085
Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase of miR-210 in lung adenocarcinoma cells and their exosomes., PMID:25263437
For research use only. Not for human or drug use.
