Catalog No.
YHJ21201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu528-Ser789
Predicted molecular weight
31.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8N3E9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PLCD3, Phosphoinositide phospholipase C-delta-3, Phospholipase C-delta-3, PLC-delta-3, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3, KIAA1964
Unraveling sex differences in Alzheimer's disease and related endophenotypes with brain proteomes., PMID:40346727
PLCD3 inhibits apoptosis and promotes proliferation, invasion and migration in gastric cancer., PMID:38305998
Revisiting Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients with Glioblastoma-Proteomic Alteration and Comparison Analysis with the Standard-of-Care Chemoirradiation., PMID:37892181
PLCD3 promotes malignant cell behaviors in esophageal squamous cell carcinoma via the PI3K/AKT/P21 signaling., PMID:37773107
A novel telomere-related gene prognostic signature for survival and drug treatment efficiency prediction in lung adenocarcinoma., PMID:37589509
Circ_0003747 promotes thyroid cancer progression by sponging miR-338-3p to upregulate PLCD3 expression., PMID:37166441
Analysis of the regulatory role of miR-34a-5p/PLCD3 in the progression of osteoarthritis., PMID:37079115
Cross-Trait Genetic Analyses Indicate Pleiotropy and Complex Causal Relationships between Headache and Thyroid Function Traits., PMID:36672757
CircMAP3K4 protects human lens epithelial cells from H2O2-induced dysfunction by targeting miR-193a-3p/PLCD3 axis in age-related cataract., PMID:36071682
Effectiveness of bortezomib and temozolomide for eradication of recurrent human glioblastoma cells, resistant to radiation., PMID:34689859
Phospholipase C Delta 3 inhibits apoptosis and promotes proliferation, migration, and invasion of thyroid cancer cells via Hippo pathway., PMID:33674820
Noteworthy prognostic value of phospholipase C delta genes in early stage pancreatic ductal adenocarcinoma patients after pancreaticoduodenectomy and potential molecular mechanisms., PMID:31808619
LncRNA PLCD3-OT1 Functions as a CeRNA to Prevent Age-Related Cataract by Sponging miR-224-5p and Regulating PLCD3 Expression., PMID:31725166
PLCD3, a flotillin2-interacting protein, is involved in proliferation, migration and invasion of nasopharyngeal carcinoma cells., PMID:29115528
Whole genome scan reveals the genetic signature of African Ankole cattle breed and potential for higher quality beef., PMID:28183280
Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia., PMID:26853712
Simultaneous loss of phospholipase Cδ1 and phospholipase Cδ3 causes cardiomyocyte apoptosis and cardiomyopathy., PMID:24810051
Alopecia in a viable phospholipase C delta 1 and phospholipase C delta 3 double mutant., PMID:22723964
Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk., PMID:22137330
Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women., PMID:22071413
Phospholipase Cdelta3 regulates RhoA/Rho kinase signaling and neurite outgrowth., PMID:21187285
Phospholipase Cδ3 is a novel binding partner of myosin VI and functions as anchoring of myosin VI on plasma membrane., PMID:21035487
Common variants in or near FGF5, CYP17A1 and MTHFR genes are associated with blood pressure and hypertension in Chinese Hans., PMID:20852445
Transcriptional profiling of septal wall of the right ventricular outflow tract in patients with idiopathic ventricular arrhythmias., PMID:19889179
Genome-wide association study identifies eight loci associated with blood pressure., PMID:19430483
Expression and function of phospholipase C in breast carcinoma., PMID:19344632
Phosphoinositide cycle gene polymorphisms affect the plasma lipid profile in the Quebec Family Study., PMID:19329342
Phospholipase C isoforms are localized at the cleavage furrow during cytokinesis., PMID:17041247
IL-2 and IL-10 production by human CD4+T cells is differentially regulated by p38: mode of stimulation-dependent regulation of IL-2., PMID:15249725
Phospholipase C delta-type consists of three isozymes: bovine PLCdelta2 is a homologue of human/mouse PLCdelta4., PMID:15219862
Membrane targeting of C2 domains of phospholipase C-delta isoforms., PMID:11706040
Downregulation of phospholipase C delta3 by cAMP and calcium., PMID:11500033
Assignment of the human PLC delta3 gene (PLCD3) to human chromosome band 17q21 by fluorescence in situ hybridization., PMID:10702670
Phospholipase C-delta3 binds with high specificity to phosphatidylinositol 4,5-bisphosphate and phosphatidic acid in bilayer membranes., PMID:10336610
Localization of phospholipase C delta3 in the cell and regulation of its activity by phospholipids and calcium., PMID:9799116
Phospholipase C isoforms delta 1 and delta 3 from human fibroblasts. High-yield expression in Escherichia coli, simple purification, and properties., PMID:9056492
Expression, purification and kinetic properties of human recombinant phospholipase C delta 3., PMID:9360711
For research use only. Not for human or drug use.
