Catalog No.
YHJ17701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu2685-Gln2850
Predicted molecular weight
19.17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q86YZ3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HRNR, Hornerin, S100A18
DEAD-Box Helicase 6 Blockade in Brain-Derived Aβ Oligomers From Alzheimer's Disease Patients Attenuates Neurotoxicity., PMID:40276647
Circular RNA CDYL facilitates hepatocellular carcinoma stemness and PD-L1+ exosomes-mediated immunotherapy resistance via stabilizing hornerin protein by blocking synoviolin 1-mediated ubiquitination., PMID:40250664
Effect of tumour necrotic factor-α, interleukin-17 and interleukin-22 on the expression of filaggerin-2 and hornerin: Analysis of a three-dimensional psoriatic skin model., PMID:39624730
A N7-methylguanosine modified circular RNA, circIPP2A2, promotes malignant behaviors in hepatocellular carcinoma by serving as a scaffold in modulating the Hornerin/PI3K/AKT/GSK3β axis., PMID:39616161
Immune response to topical sodium lauryl sulfate differs from classical irritant and allergic contact dermatitis., PMID:39498726
A meta-analysis of bulk RNA-seq datasets identifies potential biomarkers and repurposable therapeutics against Alzheimer's disease., PMID:39433822
Clinical Significance of HRNR Expression in Patients With Stage II/III Gastric Cancer After Curative Gastrectomy., PMID:39348954
Urine biomarkers can predict prostate cancer and PI-RADS score prior to biopsy., PMID:39103428
Mutational profile evaluates metastatic capacity of Chinese colorectal cancer patients, revealed by whole-exome sequencing., PMID:38492821
Cerebrospinal fluid proteomic signatures are associated with symptom severity of first-episode psychosis., PMID:38340697
Comparative genomics of monotremes provides insights into the early evolution of mammalian epidermal differentiation genes., PMID:38228724
Microbial, proteomic, and metabolomic profiling of the estrous cycle in wild house mice., PMID:38171017
Expression of hornerin in skin lesions of atopic dermatitis and skin diseases., PMID:38123340
Identification of molecular biomarkers associated with non-small-cell lung carcinoma (NSCLC) using whole-exome sequencing., PMID:37694353
Altered expression of S100 fused-type proteins in an atopic dermatitis skin model., PMID:36995036
PROK2, HRNR, and FIG4 as potential genetic biomarkers of high bleeding propensity in East Asian patients with acute coronary syndrome using ticagrelor., PMID:36263704
Effects of Autophagy Modulators and Dioxin on the Expression of Epidermal Differentiation Proteins on Psoriasis-Like Keratinocytes in vitro and ex vivo., PMID:35769934
Genomic analyses reveal SCN7A is associated with the prognosis of esophageal squamous cell carcinoma., PMID:34993672
A proximity proteomics screen in three-dimensional spheroid cultures identifies novel regulators of lumen formation., PMID:34815476
Ichthyosis: case report in a Colombian man with genetic alterations in ABCA12 and HRNR genes., PMID:34039366
Exome-Wide Association Analysis Suggests LRP2BP as a Susceptibility Gene for Endothelial Injury in Systemic Sclerosis in the Han Chinese Population., PMID:33069728
Could cellular and signaling abnormalities converge to provoke atopic dermatitis?, PMID:33048449
Expression Profiles of Genes Encoding Cornified Envelope Proteins in Atopic Dermatitis and Cutaneous T-Cell Lymphomas., PMID:32213830
Exome sequencing identifies novel mutation signatures of UV radiation and trichostatin A in primary human keratinocytes., PMID:32188867
Transient epidermal barrier deficiency and lowered allergic threshold in filaggrin-hornerin (FlgHrnr-/- ) double-deficient mice., PMID:30828807
Hornerin contains a Linked Series of Ribosome-Targeting Peptide Antibiotics., PMID:30385807
High Order Formation and Evolution of Hornerin in Primates., PMID:30256937
Evaluation of Single Nucleotide Variants in Ethiopian Patients with Atopic Dermatitis., PMID:30251743
Hornerin promotes tumor progression and is associated with poor prognosis in hepatocellular carcinoma., PMID:30103712
[Progress in fungal polyketide biosynthesis]., PMID:29424130
Expression and Regulation of S100 Fused-Type Protein Hornerin at the Ocular Surface and Lacrimal Apparatus., PMID:29183042
Identification of the S100 fused-type protein hornerin as a regulator of tumor vascularity., PMID:28916756
Identification of biomarker sets for predicting the efficacy of sublingual immunotherapy against pollen-induced allergic rhinitis., PMID:28575522
Deimination of Human Hornerin Enhances its Processing by Calpain-1 and its Cross-Linking by Transglutaminases., PMID:27742573
Atopic Dermatitis Susceptibility Variants in Filaggrin Hitchhike Hornerin Selective Sweep., PMID:27678121
In vitro effects of sex hormones in human meibomian gland epithelial cells., PMID:27569371
Discovery of serum protein biomarkers in drug-free patients with major depressive disorder., PMID:27105922
Association of a Single Nucleotide Polymorphism in a Late Cornified Envelope-like Proline-rich 1 Gene (LELP1) with Atopic Dermatitis., PMID:26608070
Whole-exome sequencing of Ethiopian patients with ichthyosis vulgaris and atopic dermatitis., PMID:25819062
In a three-dimensional reconstructed human epidermis filaggrin-2 is essential for proper cornification., PMID:25695608
Antioxidant soybean tar Glyteer rescues T-helper-mediated downregulation of filaggrin expression via aryl hydrocarbon receptor., PMID:25482884
The changes of Proteome in MG-63 cells after induced by calcitonin gene-related peptide., PMID:25305488
A fluorimetric readout reporting the kinetics of nucleotide-induced human ribonucleotide reductase oligomerization., PMID:25256246
The hand eczema proteome: imbalance of epidermal barrier proteins., PMID:25244099
Ultraviolet B irradiation induces the expression of hornerin in xenotransplanted human skin., PMID:23751202
Association of the chromosome 11q13.5 variant with atopic dermatitis in Austrian patients., PMID:23557745
Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin., PMID:23403047
Clofarabine targets the large subunit (α) of human ribonucleotide reductase in live cells by assembly into persistent hexamers., PMID:22840768
Hornerin, an S100 family protein, is functional in breast cells and aberrantly expressed in breast cancer., PMID:22727333
Expression profile of cornified envelope structural proteins and keratinocyte differentiation-regulating proteins during skin barrier repair., PMID:22329734
For research use only. Not for human or drug use.
