Catalog No.
YHJ17501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser354
Predicted molecular weight
42.59 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q86YM7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Homer protein homolog 1, HOMER1, Homer-1, SYN47
A Novel Signature Composed of Hypoxia, Glycolysis, Lactylation Related Genes to Predict Prognosis and Immunotherapy in Hepatocellular Carcinoma., PMID:40302343
Early α-synuclein aggregation decreases corticostriatal glutamate drive and synapse density., PMID:40250719
ELK4 induced upregulation of HOMER3 promotes the proliferation and metastasis in glioma via Wnt/β-catenin/EMT signaling pathway., PMID:40205485
Calcium-sensing receptors promoted Homer1 expression and osteogenic differentiation in bone marrow mesenchymal stem cells., PMID:40059879
Expression pattern of Arc in the hippocampus of a rat model of epilepsy and depression comorbidity., PMID:40023450
Thrombelastography and Serum Homer1 to Assess Hemorrhagic Transformation After Thrombolysis in Acute Ischemic Stroke., PMID:39967522
Temporal Trends in Serum Homer1 Levels and Their Prognostic Implications in Aneurysmal Subarachnoid Hemorrhage: A Prospective Cohort Study., PMID:39911298
DNA2 knockout aggravates cerebral ischemia/reperfusion injury by reducing postsynaptic Homer1a., PMID:39846189
Corrigendum: Gestational hypothyroxinemia induces ASD-like phenotypes in behavior, proinflammatory markers, and glutamatergic protein expression in mouse offspring of both sexes., PMID:39726846
CA1 ensembles expressing immediate-early genes are driven by context switch, shrink with sustained presence, and show no effect of change of task demands., PMID:39710210
Single-Nucleus RNA Sequencing Reveals That Gabra6+ Neurons in Prefrontal Cortex Promote the Progression of PTSD After Shockwave-Induced TBI., PMID:39665190
Aberrant encoding of event saliency in the orbitofrontal cortex following loss of the psychiatric-associated circular RNA, circHomer1., PMID:39609379
Thioctic acid shield against lipopolysaccharide depression and endoplasmic reticulum stress: GR7M/Homer/ATF6 signaling., PMID:39584686
Polyploid cancer cells reveal signatures of chemotherapy resistance., PMID:39578659
Genomic regions and biological mechanisms underlying climatic resilience traits derived from automatically-recorded vaginal temperature in lactating sows under heat stress conditions., PMID:39574795
Polyploid cancer cells reveal signatures of chemotherapy resistance., PMID:39483900
Polyploid cancer cells reveal signatures of chemotherapy resistance., PMID:39229204
The mGluR5-mediated Arc activation protects against experimental traumatic brain injury in rats., PMID:39107945
The noncoding circular RNA circHomer1 regulates synaptic development and experience-dependent plasticity in mouse visual cortex., PMID:39091722
Elaboration of the Homer1 recognition landscape reveals incomplete divergence of paralogous EVH1 domains., PMID:38989636
FAT1 as a tumor mutation burden specific gene affects the immunotherapy effect in head and neck squamous cell cancer., PMID:38986165
Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo., PMID:38769196
Perinatal stress modulates glutamatergic functional connectivity: A post-synaptic density immediate early gene-based network analysis., PMID:38762163
Gestational hypothyroxinemia induces ASD-like phenotypes in behavior, proinflammatory markers, and glutamatergic protein expression in mouse offspring of both sexes., PMID:38752179
HOMER1 Polymorphism and Parkinson's Disease-Psychosis: Is there an Association?, PMID:38751916
Quantitative proteomics of dorsolateral prefrontal cortex reveals an early pattern of synaptic dysmaturation in children with idiopathic autism., PMID:38696595
Changes in SLITRK1 Level in the Amygdala Mediate Chronic Neuropathic Pain-Induced Anxio-Depressive Behaviors in Mice., PMID:38682225
Elaboration of the Homer1 Recognition Landscape Reveals Incomplete Divergence of Paralogous EVH1 Domains., PMID:38645240
Extracellular vesicle encapsulated Homer1a as novel nanotherapeutics against intracerebral hemorrhage in a mouse model., PMID:38582897
Preso enhances mGluR1-mediated excitotoxicity by modulating the phosphorylation of mGluR1-Homer1 complex and facilitating an ER stress after traumatic brain injury., PMID:38531909
A single 24 h maternal separation at PND 9 promotes behavioral resilience of female C57BL/6J mice and the possible role of hippocampal Homer1a., PMID:38455582
CircRNAs in Alzheimer's disease: What are the prospects?, PMID:38125754
Homer 1 genotype AA variant relates to congenital splay leg syndrome in piglets by repressing Pax7 in myogenic progenitors., PMID:38099002
Homer1 ameliorates ischemic stroke by inhibiting necroptosis-induced neuronal damage and neuroinflammation., PMID:38091015
Homer1 Protects against Retinal Ganglion Cell Pyroptosis by Inhibiting Endoplasmic Reticulum Stress-Associated TXNIP/NLRP3 Inflammasome Activation after Middle Cerebral Artery Occlusion-Induced Retinal Ischemia., PMID:38069134
Homer1a reduces inflammatory response after retinal ischemia/reperfusion injury., PMID:38051906
Low-dose PLX5622 treatment prevents neuroinflammatory and neurocognitive sequelae after sepsis., PMID:38041192
Influence of metabolic stress and metformin on synaptic protein profile in SH-SY5Y-derived neurons., PMID:38010200
High-Content Screening of Synaptic Density Modulators in Primary Neuronal Cultures., PMID:37882787
Effect of SKF96365 on Myocardial Fibrosis in Type-II Diabetic Rats., PMID:37796683
The protective role of sulforaphane and Homer1a in retinal ischemia-reperfusion injury: Unraveling the neuroprotective interplay., PMID:37487941
Blunted type-5 metabotropic glutamate receptor-mediated polyphosphoinositide hydrolysis in two mouse models of monogenic autism., PMID:37392820
Epigenomic analysis of Alzheimer's disease brains reveals diminished CTCF binding on genes involved in synaptic organization., PMID:37302762
Postsynaptic Protein Shank3a Deficiency Synergizes with Alzheimer's Disease Neuropathology to Impair Cognitive Performance in the 3xTg-AD Murine Model., PMID:37253603
Transcriptome Analysis Reveals the Age-Related Developmental Dynamics Pattern of the Longissimus Dorsi Muscle in Ningxiang Pigs., PMID:37239410
hsa_circ_0006916 Exerts Effect on Amyloid Beta-Induced Neuron Injury by Targeting miR-217/HOMER1., PMID:37094855
Comparative Study of Time-Dependent Aluminum Exposure and Post-Exposure Recovery Shows Better Improvement in Synaptic Changes and Neuronal Pathology in Rat Brain After Short-Term Exposure., PMID:37093344
Subtype classification based on t cell proliferation-related regulator genes and risk model for predicting outcomes of lung adenocarcinoma., PMID:37077919
Genetic mapping identifies Homer1 as a developmental modifier of attention., PMID:36993710
Quantitative DNA-PAINT imaging of AMPA receptors in live neurons., PMID:36936077