Catalog No.
YHJ15001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr30-Ala399
Predicted molecular weight
44.07 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q86SJ2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Differentially expressed in gastric adenocarcinomas, AMIGO-2, AMIGO2, Amphoterin-induced protein 2, DEGA, ALI1, Alivin-1
Mendelian randomization analysis of the causal relationship between plasma proteins and childhood asthma., PMID:40193678
Hepatic Stellate Cells Activated by Cancer Cell-derived AMIGO2-containing Small Extracellular Vesicles Promote Cancer Cell Migration by Producing IL-8., PMID:40155010
Perineuronal Nets on CA2 Pyramidal Cells and Parvalbumin-Expressing Cells Differentially Regulate Hippocampal-Dependent Memory., PMID:39740999
Perineuronal nets on CA2 pyramidal cells and parvalbumin-expressing cells differentially regulate hippocampal dependent memory., PMID:39574580
Prevention of liver metastasis via the pharmacological suppression of AMIGO2 expression in tumor cells., PMID:39548119
AMIGO2 characterizes cancer-associated fibroblasts in metastatic colon cancer and induces the release of paracrine active tumorigenic secretomes., PMID:39523830
AMIGO2 enhances the invasive potential of colorectal cancer by inducing EMT., PMID:39379686
Role of AMIGO2 in cancer progression: Novel insights (Review)., PMID:39049987
A Targetable Secreted Neural Protein Drives Pancreatic Cancer Metastatic Colonization and HIF1α Nuclear Retention., PMID:39028915
Knockdown of AMIGO2 suppresses proliferation and migration through regulating PPAR-γ in bladder cancer., PMID:38978149
AMIGO2 is involved in the spread of peritoneal metastasis in serous ovarian cancer via promoting adhesion to the peritoneal mesothelial cells., PMID:38811439
METTL3 knockdown suppresses RA-FLS activation through m6A-YTHDC2-mediated regulation of AMIGO2., PMID:38432455
The METTL3-m6A-YTHDC1-AMIGO2 axis contributes to cell proliferation and migration in esophageal squamous cell carcinoma., PMID:38360124
AMIGO2 is a pivotal therapeutic target related to M2 polarization of macrophages in pancreatic ductal adenocarcinoma., PMID:38189855
AMIGO2 attenuates innate cisplatin sensitivity by suppression of GSDME-conferred pyroptosis in non-small cell lung cancer., PMID:37438979
A Novel Cuproptosis-Associated Gene Signature to Predict Prognosis in Patients with Pancreatic Cancer., PMID:36714025
Construction of a novel choline metabolism-related signature to predict prognosis, immune landscape, and chemotherapy response in colon adenocarcinoma., PMID:36451813
Liver Metastasis Formation Is Defined by AMIGO2 Expression via Adhesion to Hepatic Endothelial Cells in Human Gastric and Colorectal Cancer Cells., PMID:35843033
A dorsal CA2 to ventral CA1 circuit contributes to oxytocinergic modulation of long-term social recognition memory., PMID:35811321
Adhesion molecule Amigo2 is involved in the fasciculation process of the fasciculus retroflexus., PMID:35727300
Mechanical Strain Induces Transcriptomic Reprogramming of Saphenous Vein Progenitors., PMID:35711359
The impact of AMIGO2 on prognosis and hepatic metastasis in gastric cancer patients., PMID:35296279
AMIGO1 Promotes Axon Growth and Territory Matching in the Retina., PMID:35169021
Establishment of an antibody specific for AMIGO2 improves immunohistochemical evaluation of liver metastases and clinical outcomes in patients with colorectal cancer., PMID:35094710
AMIGO2 contained in cancer cell-derived extracellular vesicles enhances the adhesion of liver endothelial cells to cancer cells., PMID:35039535
Dysregulated BMP2 in the Placenta May Contribute to Early-Onset Preeclampsia by Regulating Human Trophoblast Expression of Extracellular Matrix and Adhesion Molecules., PMID:34970543
CDK7 and MITF repress a transcription program involved in survival and drug tolerance in melanoma., PMID:34296805
SFPQ promotes an oncogenic transcriptomic state in melanoma., PMID:34218270
Kv2 channel-AMIGO β-subunit assembly modulates both channel function and cell adhesion molecule surface trafficking., PMID:34137443
The identification of neutrophils-mediated mechanisms and potential therapeutic targets for the management of sepsis-induced acute immunosuppression using bioinformatics., PMID:33761636
Genome-Wide DNA Methylation Analysis of a Cohort of 41 Patients Affected by Oculo-Auriculo-Vertebral Spectrum (OAVS)., PMID:33530447
In vivo selection of highly metastatic human ovarian cancer sublines reveals role for AMIGO2 in intra-peritoneal metastatic regulation., PMID:33524500
AMIGO2 Expression as a Potential Prognostic Biomarker for Gastric Cancer., PMID:33288564
Methylphenidate effects on mice odontogenesis and connections with human odontogenesis., PMID:32869117
Proteomic Classification and Identification of Proteins Related to Tissue Healing of Platelet-Rich Plasma., PMID:32117548
AMIGO2 Scales Dendrite Arbors in the Retina., PMID:31693896
Impact of Astrocyte Depletion upon Inflammation and Demyelination in a Murine Animal Model of Multiple Sclerosis., PMID:31409036
A novel nonsense substitution identified in the AMIGO2 gene in an Occulo-Auriculo-Vertebral spectrum patient., PMID:31074142
Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo., PMID:29924804
Loss of AMIGO2 causes dramatic damage to cardiac preservation after ischemic injury., PMID:29718531
Colorectal cancer stages transcriptome analysis., PMID:29182684
Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene., PMID:29149598
Linking site-specific loss of histone acetylation to repression of gene expression by the mycotoxin ochratoxin A., PMID:29098329
Identification of molecular biomarkers for pancreatic cancer with mRMR shortest path method., PMID:28611293
Amigo2-upregulation in Tumour Cells Facilitates Their Attachment to Liver Endothelial Cells Resulting in Liver Metastases., PMID:28272394
AMIGO2 modulates T cell functions and its deficiency in mice ameliorates experimental autoimmune encephalomyelitis., PMID:28119027
Perineuronal Nets Suppress Plasticity of Excitatory Synapses on CA2 Pyramidal Neurons., PMID:27277807
AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation., PMID:26553931
MiR-183 Regulates ITGB1P Expression and Promotes Invasion of Endometrial Stromal Cells., PMID:26357653
Transcriptomic-anatomic analysis of the mouse habenula uncovers a high molecular heterogeneity among neurons in the lateral complex, while gene expression in the medial complex largely obeys subnuclear boundaries., PMID:25244943
For research use only. Not for human or drug use.
