Catalog No.
YHJ13401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser546-Asp669
Predicted molecular weight
16.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q7RTS9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dymeclin, Dyggve-Melchior-Clausen syndrome protein, DYM
A Cryo-Electron Microscopy structure of yeast Pex5 in complex with a cargo uncovers a novel binding interface., PMID:40376748
Cathepsin X is a conserved cell death protein involved in algal response to environmental stress., PMID:40233752
CARD domains mediate anti-phage defence in bacterial gasdermin systems., PMID:39880956
The Potential of Defatted Yellow Mealworm (Tenebrio molitor) Meal as an Alternative Protein Source for Juvenile Chinese Mitten Crab (Eriocheir sinensis)., PMID:39555548
Further defining the molecular spectrum and long-term follow-up of 17 patients with Dyggve-Melchior-Clausen and Smith-McCort dysplasia type 2., PMID:38860472
Omalizumab for the Treatment of Multiple Food Allergies., PMID:38407394
VWD domain stabilization by autocatalytic Asp-Pro cleavage., PMID:38380729
Innate antiviral responses against Shaan virus infection in HEK293, A549 and MARC-145 cells and limited role of viperin against Shaan virus replication., PMID:38076073
Reactive Oxygen Species Modulator 1 Plays an Obligate Role in Cardiomyocyte Hypertrophy., PMID:38018429
The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase., PMID:37860961
PGR5-LIKE PHOTOSYNTHETIC PHENOTYPE1A redox states alleviate photoinhibition during changes in light intensity., PMID:37787609
Specific Learning Disorders: Variation Analysis of 15 Candidate Genes in 9 Multiplex Families., PMID:37629793
Diversity of CysD domains in gel-forming mucins., PMID:37526947
Stable Mammalian Serum Albumins Designed for Bacterial Expression., PMID:37385581
A Rab33b missense mouse model for Smith-McCort dysplasia shows bone resorption defects and altered protein glycosylation., PMID:37359363
CLIC4 Regulates Endothelial Barrier Control by Mediating PAR1 Signaling via RhoA., PMID:37317855
Allosteric communication between ligand binding domains modulates substrate inhibition in adenylate kinase., PMID:37094144
A Novel Homozygous Nonsense Variant in the DYM Underlies Dyggve-Melchior-Clausen Syndrome in Large Consanguineous Family., PMID:36833437
Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer., PMID:36585453
Herd and animal factors affect the variability of total and differential somatic cell count in bovine milk., PMID:36516415
Allergen recognition by specific effector Th2 cells enables IL-2-dependent activation of regulatory T-cell responses in humans., PMID:36089900
A Novel Triple-Action Inhibitor Targeting B-Cell Receptor Signaling and BRD4 Demonstrates Preclinical Activity in Chronic Lymphocytic Leukemia., PMID:35743155
[Clinical and genetic analysis of a Chinese pedigree affected with Dyggve-Melchior-Clausen syndrome due to a novel frameshift variant of DYM gene]., PMID:35446968
The identification and characterization of an oxalyl-CoA synthetase from grass pea (Lathyrus sativus L.)., PMID:35359497
Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea., PMID:35271851
Computationally designed dual-color MRI reporters for noninvasive imaging of transgene expression., PMID:35102291
Expression of SARS-CoV-2 Spike Protein Receptor Binding Domain on Recombinant B. subtilis on Spore Surface: A Potential COVID-19 Oral Vaccine Candidate., PMID:35062663
Bilateral Severe Genu Varum in Dyggve-Melchior-Clausen Syndrome - A Case Report., PMID:35004383
SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution., PMID:34400835
Overexpression of miR-122 Impairs Intestinal Barrier Function and Aggravates Acute Pancreatitis by Downregulating Occludin Expression., PMID:34235595
Bromodomain and Extraterminal Protein Inhibitor, Apabetalone (RVX-208), Reduces ACE2 Expression and Attenuates SARS-Cov-2 Infection In Vitro., PMID:33919584
Community-Wide Experimental Evaluation of the PROSS Stability-Design Method., PMID:33781758
A Molecular Lid Mechanism of K+ Channel Blocker Action Revealed by a Cone Peptide., PMID:33771569
IceBear: an intuitive and versatile web application for research-data tracking from crystallization experiment to PDB deposition., PMID:33559605
Maxillofacial Bone Grafting Materials: 2021 Update., PMID:33213708
A homozygous nonsense variant in DYM underlies Dyggve-Melchior-Clausen syndrome associated with ectodermal features., PMID:32886330
Plasma Circular RNA DYM Related to Major Depressive Disorder and Rapid Antidepressant Effect Treated by Visual Cortical Repetitive Transcranial Magnetic Stimulation., PMID:32663980
Maxillofacial Bone Grafting Materials., PMID:32111281
Enzyme Evolution: An Epistatic Ratchet versus a Smooth Reversible Transition., PMID:31873734
Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC., PMID:31852845
Safety, Tolerability, Pharmacokinetics, Target Occupancy, and Concentration-QT Analysis of the Novel BTK Inhibitor Evobrutinib in Healthy Volunteers., PMID:31654487
Pore-modulating toxins exploit inherent slow inactivation to block K+ channels., PMID:31444298
Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces., PMID:31442220
The four-helix bundle in cholinesterase dimers: Structural and energetic determinants of stability., PMID:31202688
Whole-genome analysis identifying candidate genes of altitude adaptive ecological thresholds in yak populations., PMID:31062447
Ultrahigh specificity in a network of computationally designed protein-interaction pairs., PMID:30538236
RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma., PMID:30478445
CircDYM ameliorates depressive-like behavior by targeting miR-9 to regulate microglial activation via HSP90 ubiquitination., PMID:30413800
Automated Design of Efficient and Functionally Diverse Enzyme Repertoires., PMID:30270109
Manipulating the Folding Landscape of a Multidomain Protein., PMID:30088929
For research use only. Not for human or drug use.
