Catalog No.
YHJ13101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn29-Trp229
Predicted molecular weight
25.97 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q7LGA3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HS2ST1, HS2ST, 2OST, Heparan sulfate 2-O-sulfotransferase 1, KIAA0448, 2-O-sulfotransferase
Prognostic implications of glucose metabolism pathways in colon adenocarcinoma: a comprehensive outlook on the molecular landscape and immunotherapy., PMID:40345006
Development and Validation of a Predictive Model for Resistance to Platinum-Based Chemotherapy in Patients with Ovarian Cancer through Proteomic Analysis., PMID:39253780
Prognostic significance of HS2ST1 expression in patients with hepatocellular carcinoma., PMID:39153155
MEG3-Mediated Oral Squamous-Cell-Carcinoma-Derived Exosomal miR-421 Activates Angiogenesis by Targeting HS2ST1 in Vascular Endothelial Cells., PMID:39062818
Two novel predictive biomarkers for osteosarcoma and glycolysis pathways: A profiling study on HS2ST1 and SDC3., PMID:36086752
Prognostic significance of hedgehog signaling network-related gene expression in breast cancer patients., PMID:33417295
Chromosome 2 Fragment Substitutions in Dahl Salt-Sensitive Rats and RNA Sequencing Identified Enpep and Hs2st1 as Vascular Inflammatory Modulators., PMID:33161775
Bi-allelic Pathogenic Variants in HS2ST1 Cause a Syndrome Characterized by Developmental Delay and Corpus Callosum, Skeletal, and Renal Abnormalities., PMID:33159882
The Heparan Sulfate Sulfotransferases HS2ST1 and HS3ST2 Are Novel Regulators of Breast Cancer Stem-Cell Properties., PMID:33102470
HS2ST1-dependent signaling pathways determine breast cancer cell viability, matrix interactions, and invasive behavior., PMID:32573871
Sulfated syndecan 1 is critical to preventing cellular senescence by modulating fibroblast growth factor receptor endocytosis., PMID:32530114
BCP crystals promote chondrocyte hypertrophic differentiation in OA cartilage by sequestering Wnt3a., PMID:32371389
Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity., PMID:31940721
Changes in heparan sulfate sulfotransferases and cell-surface heparan sulfate during SKM-1 cells granulocytic differentiation and A549 cells epithelial-mesenchymal transition., PMID:31863309
Structure-based design of nucleoside-derived analogues as sulfotransferase inhibitors., PMID:35530783
Heparan Sulfate Biosynthetic System Is Inhibited in Human Glioma Due to EXT1/2 and HS6ST1/2 Down-Regulation., PMID:29104277
2- and 6-O-sulfated proteoglycans have distinct and complementary roles in cranial axon guidance and motor neuron migration., PMID:27048738
Proteoglycan expression correlates with the phenotype of malignant and non-malignant EBV-positive B-cell lines., PMID:26527314
Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature., PMID:19395651
Expression of genes encoding for proteins involved in heparan sulphate and chondroitin sulphate chain synthesis and modification in normal and malignant plasma cells., PMID:19298595
Glycogene expression in conjunctiva of patients with dry eye: downregulation of Notch signaling., PMID:19011014
Hydrogen peroxide as a potential mediator of the transcriptional regulation of heparan sulphate biosynthesis in keratinocytes., PMID:18463796
For research use only. Not for human or drug use.
