Catalog No.
YHJ11101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln522-Met784
Predicted molecular weight
56.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6ZN28
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MACC1, SH3 domain-containing protein 7a5, Metastasis-associated in colon cancer protein 1
Knockdown of MACC1 expression attenuates colorectal cancer cell glucose metabolism by suppressing GLUT4 membrane translocation., PMID:40501119
Mitochondria-related genes as prognostic signature of endometrial cancer and the effect of MACC1 on tumor cells., PMID:40354443
MACC1 is a potential prognostic biomarker for cancer immunotherapy in lung adenocarcinoma., PMID:40117327
Establishment of Stable Knockdown of MACC1 Oncogene in Patient-Derived Ovarian Cancer Organoids., PMID:39728624
LncRNA MACC1-AS1 facilitates the cell growth of small cell lung cancer by sequestering miR-579-3p and mediating NOTCH1-pathway., PMID:39401633
Innovative Therapeutic Delivery of Metastasis-Associated in Colon Cancer 1-Suppressing miRNA Using High Transmembrane 4 L6 Family Member 5-Targeting Exosomes in Colorectal Cancer Mouse Models., PMID:39273182
MACC1 enhances an oncogenic RNA splicing of IRAK1 through interacting with HNRNPH1 in lung adenocarcinoma., PMID:39221900
Induction of circulating ABCB1 transcripts under platinum-based chemotherapy indicates poor prognosis and a bone micrometastatic phenotype in ovarian cancer patients., PMID:39180062
Therapeutic targeting of voltage-gated sodium channel NaV1.7 for cancer metastasis., PMID:39045054
Prognostic risk stratification value of MACC1 expression in patients with gastric cancer., PMID:38867026
Identification of MACC1 as a potential biomarker for pulmonary arterial hypertension based on bioinformatics and machine learning., PMID:38552277
miR-330-5p Suppress Cell Growth and Invasion via Disrupting HSF4-mediated MACC1/STAT3 Pathway in Colorectal Cancer., PMID:38420805
LncRNA MACC1-AS1 induces gemcitabine resistance in pancreatic cancer cells through suppressing ferroptosis., PMID:38413579
Global Proteomics Analysis of Lysophosphatidic Acid Signaling in PC-3 Human Prostate Cancer Cells: Role of CCN1., PMID:38396744
[MACC1 knockdown enhances RSL3-induced ferroptosis in human colorectal cancer cells by inhibiting GPX4 expression]., PMID:38293989
CircXRN2 accelerates colorectal cancer progression through regulating miR-149-5p/MACC1 axis and EMT., PMID:38291092
GIPC1 regulates MACC1-driven metastasis., PMID:38144523
COX19 Is a New Target of MACC1 and Promotes Colorectal Cancer Progression by Regulating Copper Transport in Mitochondria., PMID:38141772
Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis., PMID:37865992
Metastasis Associated in Colorectal Cancer 1 (MACC1) mRNA Expression Is Enhanced in Sporadic Vestibular Schwannoma and Correlates to Deafness., PMID:37627117
Curcumin inhibits malignant behavior of colorectal cancer cells by regulating M2 polarization of tumor-associated macrophages and metastasis associated in colon cancer 1 (MACC1) expression., PMID:37599210
Long Intergenic Non-Protein Coding RNA 519 Promotes the Biological Activities of Tongue Squamous Cell Carcinoma by Sponging microRNA-876-3p and Consequently Upregulating MACC1 [Retraction]., PMID:37525843
MACC1 and MET as markers associated with progression and metastasis in cutaneous melanoma., PMID:37496665
Effects of Co-Culture EBV-miR-BART1-3p on Proliferation and Invasion of Gastric Cancer Cells Based on Exosomes., PMID:37345178
MACC1 and Gasdermin-E (GSDME) regulate the resistance of colorectal cancer cells to irinotecan., PMID:37307707
Integrative multiomics analysis identifies a metastasis-related gene signature and the potential oncogenic role of EZR in breast cancer., PMID:37304008
Cantharidin and Its Analogue Norcantharidin Inhibit Metastasis-Inducing Genes S100A4 and MACC1., PMID:36674695
MACC1-Dependent Antitumor Effect of Curcumin in Colorectal Cancer., PMID:36432477
Differences of macrophages in the tumor microenvironment as an underlying key factor in glioma patients., PMID:36389681
MACC1 promotes pancreatic cancer metastasis by interacting with the EMT regulator SNAI1., PMID:36333284
Correlation of miRNA-21 and blood Cr levels with tumor infiltration and distant metastasis in renal cancer patients., PMID:36029501
Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis., PMID:36008464
Parecoxib expresses anti-metastasis effect through inhibition of epithelial-mesenchymal transition and the Wnt/β-catenin signaling pathway in human colon cancer DLD-1 cell line., PMID:35917206
Core-Clock Genes Regulate Proliferation and Invasion via a Reciprocal Interplay with MACC1 in Colorectal Cancer Cells., PMID:35884519
MACC1 Promotes the Progression and Is a Novel Biomarker for Predicting Immunotherapy Response in Colorectal Cancer., PMID:35874635
Calcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker., PMID:35597866
Circ_0001174 facilitates osteosarcoma cell proliferation, migration, and invasion by targeting the miR-186-5p/MACC1 axis., PMID:35279159
The Relationship between MACC1/c-Met/Cyclin D1 Axis Expression and Prognosis in ESCC., PMID:35242498
Alpha-fetoprotein can promote gastric cancer progression via upregulation of metastasis-associated colon cancer 1., PMID:35126726
Circ_0002577/miR-126-5p/MACC1 axis promotes endometrial carcinoma progression by regulation of proliferation, migration, invasion, and apoptosis of endometrial carcinoma cells., PMID:35103833
IFN-γ affects pancreatic cancer properties by MACC1-AS1/MACC1 axis via AKT/mTOR signaling pathway., PMID:35037236
Obesity, colorectal cancer and MACC1 expression: A possible novel molecular association., PMID:35014688
MACC1 regulates the AKT/STAT3 signaling pathway to induce migration, invasion, cancer stemness, and suppress apoptosis in cervical cancer cells., PMID:34939526
Insulin-like Growth Factor Binding Protein-2 (IGFBP2) Is a Key Molecule in the MACC1-Mediated Platelet Communication and Metastasis of Colorectal Cancer Cells., PMID:34830078
Whole Exome Sequencing Study in a Family with Type 2 Diabetes Mellitus., PMID:34815695
A potential role for metastasis-associated in colon cancer 1 (MACC1) as a pan-cancer prognostic and immunological biomarker., PMID:34814302
Long Intergenic Non-Protein Coding RNA 519 Promotes the Biological Activities of Tongue Squamous Cell Carcinoma by Sponging microRNA-876-3p and Consequently Upregulating MACC1 [Expression of Concern]., PMID:34707372
The Prognostic Significance of MACC1 Expression in Breast Cancer and Its Relationship to Immune Cells in the Tumor Microenvironment and Patient Survival., PMID:34577857
Long Noncoding RNA LINC01703 Exacerbates the Malignant Properties of Non-Small Cell Lung Cancer by Upregulating MACC1 in a MicroRNA-605-3p-Mediated Manner., PMID:34493358
Association of MACC1 expression with lymphatic metastasis in colorectal cancer: A nested case-control study., PMID:34343214
For research use only. Not for human or drug use.
