Catalog No.
YHJ09801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly117-Ala198
Predicted molecular weight
11.85 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6UXH0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Lipasin, C19orf80, ANGPTL8, RIFL, Refeeding-induced fat and liver protein, Angiopoietin-like protein 8, Betatrophin
Mult-omics analysis reveals the lipid-lowering effects of sea buckthorn and milk thistle solid beverage in hyperlipidemic rats., PMID:40472616
Angiopoietin-like protein inhibitors: Promising agents for the treatment of familial hypercholesterolemia and atherogenic dyslipidemia., PMID:40344904
Angiopoietin-Like Protein Family-Mediated Functions in Modulating Triglyceride Metabolism and Related Metabolic Diseases., PMID:40302331
Clinical Value of Circulating Angiopoietin-like Protein 8/Betatrophin Levels in Patients with Acute Pancreatitis., PMID:40282999
Circulating angiopoietin-like protein 8 (ANGPTL8) and steatotic liver disease related to metabolic dysfunction: an updated systematic review and meta-analysis., PMID:40276549
Elevated serum asprosin and ANGPTL8 gene expression as novel biomarkers for the diagnosis and prognosis of acute coronary syndrome., PMID:40255338
Associations Between APOC3 and ANGPTL8 Gene Polymorphisms With MASLD Risk and the Mediation Effect of Triglyceride on MASLD in the Chinese Population., PMID:40192643
ANGPTL3/8 is an atypical unfoldase that regulates intravascular lipolysis by catalyzing unfolding of lipoprotein lipase., PMID:40112106
Multilayer regulation of postprandial triglyceride metabolism in response to acute cold exposure., PMID:39892721
Circulating ANGPTL3/8 Concentrations Are Associated With an Atherogenic Lipoprotein Profile and Increased CHD Risk in Swedish Population-Based Studies., PMID:39882603
Osteopontin Levels in Maternal Serum, Cord Blood, and Breast Milk According to Gestational Diabetes Mellitus: A Case-Control Study., PMID:39770956
New exploration on pathogenesis and early diagnosis of gestational diabetes., PMID:39764537
Relationship between serum levels of ANGPTL8, Apo C2, and human placental lactogen (hPL) in patients with gestational diabetes mellitus: Interaction of LPL regulators with hPL, a possible contributing factor to insulin resistance., PMID:39700905
Adipocyte Angptl8 deletion improves glucose and energy metabolism and obesity associated inflammation in mice., PMID:39640567
The mediating role of remnant cholesterol in the associations of Angiopoietin-like 8 with all-cause, CVD, and cancer death: the China Cardiometabolic Disease and Cancer Cohort (4C) study., PMID:39604542
Social Bonds Retain Oxytocin-Mediated Brain-Liver Axis to Retard Atherosclerosis., PMID:39601150
Angiopoietin-like protein 8 directs DNA damage responses towards apoptosis by stabilizing PARP1-DNA condensates., PMID:39592710
Inhibition of the ANGPTL3/8 Complex for the Prevention and Treatment of Atherosclerotic Cardiovascular Disease., PMID:39565562
Highland Barley Alleviates High-Fat Diet-Induced Obesity and Liver Injury Through the IRS2/PI3K/AKT Signaling Pathway in Rats., PMID:39458511
Adipokine/hepatokines profiling of fatty liver in adolescents and young adults: cross-sectional and prospective analyses of the BCAMS study., PMID:39400684
Associations of Circulating ANGPTL3, C-Terminal Domain-Containing ANGPTL4, and ANGPTL3/8 and ANGPTL4/8 Complexes with LPL Activity, Diabetes, Inflammation, and Cardiovascular Mortality., PMID:39392008
ASGR1 Deficiency Inhibits Atherosclerosis in Western Diet-Fed ApoE-/- Mice by Regulating Lipoprotein Metabolism and Promoting Cholesterol Efflux., PMID:39387120
The relationship between rheumatoid arthritis and epicardial fat thickness, and serum levels of chemerin, adropin, and betatrophin., PMID:39302228
Angiopoietin-like Proteins and Lipoprotein Lipase: The Waltz Partners That Govern Triglyceride-Rich Lipoprotein Metabolism? Impact on Atherogenesis, Dietary Interventions, and Emerging Therapies., PMID:39274442
The determinants of leptin, angiopoietin like 8, and thyroid hormones levels in Saudi females with type 2 diabetes mellitus: A retrospective study., PMID:39252284
Postprandial exercise regulates tissue-specific triglyceride uptake through angiopoietin-like proteins., PMID:39171527
Association between thermogenic brown fat and genes under positive natural selection in circumpolar populations., PMID:39160621
Inhibition of ANGPTL8 protects against diabetes-associated cognitive dysfunction by reducing synaptic loss via the PirB signaling pathway., PMID:39095838
Evaluation of serum levels of sestrin 2 and betatrophin in type 2 diabetic patients with diabetic nephropathy., PMID:39030467
ANGPTL8 deficiency attenuates lipopolysaccharide-induced liver injury by improving lipid metabolic dysregulation., PMID:39019343
Transcriptomic Analyses Reveal the Effects of Walnut Kernel Cake on Adipose Deposition in Pigs., PMID:38927603
Triglyceride-rich lipoprotein, remnant cholesterol, and apolipoproteins CII, CIII, and E in patients with schizophrenia., PMID:38879166
The correlations between angiopoietin like 8 and cardiometabolic risk factors in Saudi women with type 2 diabetes mellitus: A pilot study., PMID:38843864
Dyslipidemia and ANGPTL8 evaluation in young females with Type 1 diabetes mellitus., PMID:38836992
Angiopoietin-2 and Angiopoietin-like Proteins with a Prospective Role in Predicting Diabetic Nephropathy., PMID:38790911
Thrombospondin-2 as a potential noninvasive biomarker of hepatocyte injury but not liver fibrosis in children with MAFLD: A preliminary study., PMID:38774195
Association Between rs2278426 Polymorphism of the ANGPTL8 Gene and Polycystic Ovary Syndrome., PMID:38645655
Predictive value of angiopoietin-like protein 8 in metabolic dysfunction-associated fatty liver disease and its progression: A case-control study., PMID:38591072
Serum proteins differentially expressed in gestational diabetes mellitus assessed using isobaric tag for relative and absolute quantitation proteomics., PMID:38576811
The minor allele of ANGPTL8 rs2278426 has a protective effect against CAD in T2DM patients., PMID:38552749
A unified model for regulating lipoprotein lipase activity., PMID:38521668
Characterization of sexual dimorphism in ANGPTL4 levels and function., PMID:38431115
Eight weeks of daily cottonseed oil intake attenuates postprandial angiopoietin-like proteins 3 and 4 responses compared to olive oil in adults with hypercholesterolemia: A secondary analysis of a randomized clinical trial., PMID:38295507
Silencing ANGPTL8 reduces mouse preadipocyte differentiation and insulin signaling., PMID:38272177
Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner., PMID:38211696
Positive correlation of ANGPTL8 expression in human visceral adipose tissue with body mass index., PMID:38191275
Adolescent obesity and ANGPTL8: correlations with high sensitivity C-reactive protein, leptin, and chemerin., PMID:38189043
Emerging insights into the roles of ANGPTL8 beyond glucose and lipid metabolism., PMID:38107478
Correlation Between the Levels of ANGPTL3, ANGPTL4, ANGPTL8 and Postprandial Triglyceride-Rich Lipoprotein (TRL)., PMID:38084361
Gender-Dependent Associations between Serum Betatrophin Levels and Lipoprotein Subfractions in Diabetic and Nondiabetic Obese Patients., PMID:38003693
For research use only. Not for human or drug use.
