Catalog No.
YHJ06501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro41-Phe271
Predicted molecular weight
28.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6P179
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ERAP2, Endoplasmic reticulum aminopeptidase 2, Leukocyte-derived arginine aminopeptidase, LRAP, L-RAP
Black Death protective gene mutation shows ambiguous role in type 1 diabetes, its complications, and common viral infections., PMID:40449626
An integrated multi-omics analysis identifies protein biomarkers and potential drug targets for psoriatic arthritis., PMID:39953266
The important roles of ERAP1, ERAP2 genes polymorphisms and their DNA methylation levels in pulmonary tuberculosis., PMID:39910453
Association of ERAP1 and ERAP2 gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population., PMID:39906739
Elucidating the mechanism of phthalates induced osteoporosis through network toxicology and molecular docking., PMID:39884015
Defining a genetic background for bamboo spine and axial spondyloarthritis., PMID:39828050
Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint., PMID:39561763
Mendelian Randomization Estimates the Effects of Plasma and Cerebrospinal Fluid Proteins on Intelligence, Fluid Intelligence Score, and Cognitive Performance., PMID:39495227
The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response., PMID:39123229
Identification of immune-inflammation targets for intracranial aneurysms: a multiomics and epigenome-wide study integrating summary-data-based Mendelian randomization, single-cell-type expression analysis, and DNA methylation regulation., PMID:39051921
The association between endoplasmic reticulum aminopeptidase 2 gene single nucleotide polymorphisms and the risk of psoriasis and psoriatic arthritis in Egyptians., PMID:39046539
ERAP Inhibitors in Autoimmunity and Immuno-Oncology: Medicinal Chemistry Insights., PMID:39011823
Integrating plasma proteomics with genome-wide association data to identify novel drug targets for inflammatory bowel disease., PMID:39009667
Epistatic interaction between ERAP2 and HLA modulates HIV-1 adaptation and disease outcome in an Australian population., PMID:38980912
Identification of immune- and oxidative stress-related signature genes as potential targets for mRNA vaccines for pancreatic cancer patients., PMID:38968513
A study of the association between single nucleotide polymorphisms of the endoplasmic reticulum aminopeptidase 2 (ERAP2) gene and the risk of ankylosing spondylitis in Egyptians., PMID:38704785
ERAP1 and ERAP2 gene variants as potential clinical biomarkers of anti-interleukin-17A response in psoriasis vulgaris., PMID:38616723
The Role of Aminopeptidase ERAP1 in Human Pathology-A Review., PMID:38534723
Innovate therapeutic targets for autoimmune diseases: insights from proteome-wide mendelian randomization and Bayesian colocalization., PMID:38515381
ERAP-1 and ERAP-2 Variants in Liver Injury After COVID-19 mRNA Vaccination: A US Multicenter Study., PMID:38314748
Endoplasmic reticulum aminopeptidase 2 regulates CD4+ T cells pyroptosis in rheumatoid arthritis., PMID:38273310
A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs., PMID:38190099
Evolutionary immuno-genetics of endoplasmic reticulum aminopeptidase II (ERAP2)., PMID:37925533
ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-Epitopes., PMID:37686141
Critical genes in human photoaged skin identified using weighted gene co-expression network analysis., PMID:37454939
Discovery of Biomarkers for Amyotrophic Lateral Sclerosis from Human Cerebrospinal Fluid Using Mass-Spectrometry-Based Proteomics., PMID:37238921
Juvenile idiopathic arthritis-associated genetic loci exhibit spatially constrained gene regulatory effects across multiple tissues and immune cell types., PMID:37229810
M1-aminopeptidase family - beyond antigen-trimming activities., PMID:37216842
The role of endoplasmic reticulum aminopeptidases in type 1 diabetes mellitus., PMID:37059356
EULAR study group on 'MHC-I-opathy': identifying disease-overarching mechanisms across disciplines and borders., PMID:36987655
Potential diagnostic markers and therapeutic targets for rheumatoid arthritis with comorbid depression based on bioinformatics analysis., PMID:36911710
Variation in ERAP2 has opposing effects on severe respiratory infection and autoimmune disease., PMID:36889308
A Comparative Review of Pregnancy and Cancer and Their Association with Endoplasmic Reticulum Aminopeptidase 1 and 2., PMID:36834865
Shedding new light on the role of ERAP1 in Type 1 diabetes: A perspective on disease management., PMID:36740089
Cell-Specific and Variant-Linked Alterations in Expression of ERAP1, ERAP2, and LNPEP Aminopeptidases in Psoriasis., PMID:36716917
ERAP2 supports TCR recognition of three immunotherapy targeted tumor epitopes., PMID:36608422
Retina-arrestin specific CD8+ T cells are not implicated in HLA-A29-positive birdshot chorioretinitis., PMID:36581221
The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities., PMID:36569828
Identification of Reduced ERAP2 Expression and a Novel HLA Allele as Components of a Risk Score for Susceptibility to Liver Injury Due to Amoxicillin-Clavulanate., PMID:36496055
Construction of a mitochondrial dysfunction related signature of diagnosed model to obstructive sleep apnea., PMID:36468038
Whole-exome sequencing study identifies four novel gene loci associated with diabetic kidney disease., PMID:36444934
ERAP/HLA-C and KIR Genetic Profile in Couples with Recurrent Implantation Failure., PMID:36293373
Evolution of immune genes is associated with the Black Death., PMID:36261521
ERAP2 as a potential biomarker for predicting gemcitabine response in patients with pancreatic cancer., PMID:36214762
The emerging multifunctional roles of ERAP1, ERAP2 and IRAP between antigen processing and renin-angiotensin system modulation., PMID:36203608
Discovery of the First Selective Nanomolar Inhibitors of ERAP2 by Kinetic Target-Guided Synthesis., PMID:35904863
To Be or Not to Be: The Case of Endoplasmic Reticulum Aminopeptidase 2., PMID:35769458
Phenylsulfamoyl Benzoic Acid Inhibitor of ERAP2 with a Novel Mode of Inhibition., PMID:35767698
Newly identified genetic variants associated with idiosyncratic drug-induced liver injury., PMID:35645018
A Short ERAP2 That Binds IRAP Is Expressed in Macrophages Independently of Gene Variation., PMID:35563348
For research use only. Not for human or drug use.
