Catalog No.
YHJ06401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe512-Phe785
Predicted molecular weight
58.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6P0Q8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Microtubule-associated serine/threonine-protein kinase 2, KIAA0807, MAST2, MAST205
Clinical Outcomes and Genomic Alterations in Gleason Score 10 Prostate Cancer., PMID:40227503
DexDesign: an OSPREY-based algorithm for designing de novo D-peptide inhibitors., PMID:38757573
DexDesign: A new OSPREY-based algorithm for designing de novo D-peptide inhibitors., PMID:38405797
Microtubule-Associated Serine/Threonine (MAST) Kinases in Development and Disease., PMID:37569286
Rare-variant association analysis reveals known and new age-related hearing loss genes., PMID:36788145
Integration of transcriptome sequencing and whole genome resequencing reveal candidate genes in egg production of upright and pendulous-comb chickens., PMID:36739803
Revealing phosphorylation regulatory networks during embryogenesis of honey bee worker and drone (Apis mellifera)., PMID:36225314
Identification of fusions with potential clinical significance in melanoma., PMID:35871080
Whole Exome Sequencing Study in a Family with Type 2 Diabetes Mellitus., PMID:34815695
Dynamic Control of Signaling by Phosphorylation of PDZ Binding Motifs., PMID:34014523
PDZ Sample Quality Assessment by Biochemical and Biophysical Characterizations., PMID:34014518
Host PDZ-containing proteins targeted by SARS-CoV-2., PMID:33864728
Detection of loci exhibiting pleiotropic effects on body weight and egg number in female broilers., PMID:33811218
A rare coding mutation in the MAST2 gene causes venous thrombosis in a French family with unexplained thrombophilia: The Breizh MAST2 Arg89Gln variant., PMID:33465109
ACE2 Interaction Networks in COVID-19: A Physiological Framework for Prediction of Outcome in Patients with Cardiovascular Risk Factors., PMID:33233425
MAST1 variant causes mega-corpus-callosum syndrome with cortical malformations but without cerebellar hypoplasia., PMID:32198973
High MAST2 mRNA expression and its role in diagnosis and prognosis of liver cancer., PMID:31882722
Structure-based optimization of a PDZ-binding motif within a viral peptide stimulates neurite outgrowth., PMID:31346033
Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations., PMID:30449657
A comprehensive analysis of polymorphic variants in steroid hormone and insulin-like growth factor-1 metabolism and risk of in situ breast cancer: Results from the Breast and Prostate Cancer Cohort Consortium., PMID:29114882
Intragenic multi-exon deletion in the FBN1 gene in a child with mildly dilated aortic sinus: a retrotransposal event., PMID:28331219
Novel genes in brain tissues of EAE-induced normal and obese mice: Upregulation of metal ion-binding protein genes in obese-EAE mice., PMID:27956064
A Screen for Genomic Disorders of Infertility Identifies MAST2 Duplications Associated with Nonobstructive Azoospermia in Humans., PMID:26203179
Deciphering the unconventional peptide binding to the PDZ domain of MAST2., PMID:25942057
A novel e8a2 BCR-ABL1 fusion with insertion of MAST2 exon 2 in a four-way translocation t (1;17;9;22) (p35;q24;q44;q11) in a patient with chronic myeloid leukemia., PMID:25899399
MAST2 and NOTCH1 translocations in breast carcinoma and associated pre-invasive lesions., PMID:24140425
A functional yeast survival screen of tumor-derived cDNA libraries designed to identify anti-apoptotic mammalian oncogenes., PMID:23717670
MAST205 competes with cystic fibrosis transmembrane conductance regulator (CFTR)-associated ligand for binding to CFTR to regulate CFTR-mediated fluid transport., PMID:23504457
Interference with the PTEN-MAST2 interaction by a viral protein leads to cellular relocalization of PTEN., PMID:22894835
Transcriptional regulation of human-specific SVAF₁ retrotransposons by cis-regulatory MAST2 sequences., PMID:22609064
Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer., PMID:22101766
[MAST2-like protein kinase from grape vine Vitis vinifera: cloning of catalytic domain cDNA]., PMID:20722285
Bioinformatic search of plant microtubule-and cell cycle related serine-threonine protein kinases., PMID:20158871
Attenuation of rabies virulence: takeover by the cytoplasmic domain of its envelope protein., PMID:20086240
Novel family of human transposable elements formed due to fusion of the first exon of gene MAST2 with retrotransposon SVA., PMID:19961423
[Bioinformatic search of plant protein kinases, participating in microtubule protein phosphorylation and cell division regulation]., PMID:19938639
5'-Transducing SVA retrotransposon groups spread efficiently throughout the human genome., PMID:19652014
Exon-trapping mediated by the human retrotransposon SVA., PMID:19635844
In vivo inactivation of MASTL kinase results in thrombocytopenia., PMID:19460416
Association of genetic variation in mitotic kinases with breast cancer risk., PMID:19404734
Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen., PMID:18007665
[Identification of a novel human MAST4 gene, a new member of the microtubule associated serine-threonine kinase family]., PMID:17086981
Coexpression of MAST205 inhibits the activity of Na+/H+ exchanger NHE3., PMID:16159897
Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases., PMID:15951562