Catalog No.
YHJ03901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ile342
Predicted molecular weight
50.39 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q5VYX0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C10orf59, RNLS, Monoamine oxidase-C, Renalase, MAO-C
Pathological forms of TDP-43 in amyotrophic lateral sclerosis (ALS) promote aberrant telomere elongation., PMID:40379219
Interaction of kidney proteins of normal and hypertensive rats with fragments of renalase peptide RP220., PMID:40326017
Interaction of rat kidney proteins with the renalase peptide RP220 and its potential proteolytic fragment RP224-232: a comparative proteomic analysis., PMID:40045725
Neuronal TDP-43 aggregation drives changes in microglial morphology prior to immunophenotype in amyotrophic lateral sclerosis., PMID:39985110
Low Renalase Levels in Newly Diagnosed CML: Dysregulation Sensitive to Modulation by Tyrosine Kinase Inhibitors., PMID:39728688
Phylogenomic insights into the diversity and evolution of RPW8-NLRs and their partners in plants., PMID:39312623
Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival., PMID:39102218
Beta cells deficient for Renalase counteract autoimmunity by shaping natural killer cell activity., PMID:38975343
Proteomic profiling of renal tissue of normo- and hypertensive rats with the renalase peptide RP220 as an affinity ligand., PMID:38940203
Renalase inhibition regulates β cell metabolism to defend against acute and chronic stress., PMID:38915698
Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity., PMID:38513655
A multi-ancestry genome-wide association study in type 1 diabetes., PMID:38453145
Evaluation of some nonroutine cardiac biomarkers among adults and children with beta-thalassemia major., PMID:38417033
Renalase mediates macrophage-to-fibroblast crosstalk to attenuate pressure overload-induced pathological myocardial fibrosis., PMID:38230609
The search for potential hypotensive peptides in the amino acid sequence of human renalase and their identification in proteolytic fragments of this protein., PMID:38153055
Renalase regulates renal tubular injury in diabetic nephropathy via the p38MAPK signaling pathway., PMID:37732586
The effect of renalase-derived peptides on viability of HepG₂ and PC3 cells., PMID:37384910
Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain., PMID:37118836
Broader functions of TIR domains in Arabidopsis immunity., PMID:36893276
Plasma renalase levels are associated with the development of acute pancreatitis., PMID:36697349
Cardiac-specific renalase overexpression alleviates CKD-induced pathological cardiac remodeling in mice., PMID:36588579
RENALASE: DISCOVERY, BIOLOGY, AND THERAPEUTIC APPLICATIONS., PMID:36196172
EDS1 complexes are not required for PRR responses and execute TNL-ETI from the nucleus in Nicotiana benthamiana., PMID:36151929
Aerobic Exercise Training Improves Renal Injury in Spontaneously Hypertensive Rats by Increasing Renalase Expression in Medulla., PMID:35898283
Renalase and its receptor, PMCA4b, are expressed in the placenta throughout the human gestation., PMID:35322081
Inhibition of renalase drives tumour rejection by promoting T cell activation., PMID:35219026
Structural basis of NLR activation and innate immune signalling in plants., PMID:34981187
A new biochemistry connecting pathogen detection to induced defense in plants., PMID:34921418
Kidney-Targeted Renalase Agonist Prevents Cisplatin-Induced Chronic Kidney Disease by Inhibiting Regulated Necrosis and Inflammation., PMID:34921111
Arabidopsis ADR1 helper NLR immune receptors localize and function at the plasma membrane in a phospholipid dependent manner., PMID:34628646
How activated NLRs induce anti-microbial defenses in plants., PMID:34623378
CCR -NB-LRR proteins MdRNL2 and MdRNL6 interact physically to confer broad-spectrum fungal resistance in apple (Malus × domestica)., PMID:34610171
The Effect of Renalase rs2576178 and rs10887800 Polymorphisms on Ischemic Stroke Susceptibility in Young Patients (<50 Years): A Case-Control Study and In Silico Analysis., PMID:34603559
Renalase: A Multi-Functional Signaling Molecule with Roles in Gastrointestinal Disease., PMID:34440775
NADase and now Ca2+ channel, what else to learn about plant NLRs?, PMID:37676511
Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity., PMID:34099661
Two unequally redundant "helper" immune receptor families mediate Arabidopsis thaliana intracellular "sensor" immune receptor functions., PMID:32925907
Renalase Attenuates Mouse Fatty Liver Ischemia/Reperfusion Injury through Mitigating Oxidative Stress and Mitochondrial Damage via Activating SIRT1., PMID:31949882
Inferring RPW8-NLRs's evolution patterns in seed plants: case study in Vitis vinifera., PMID:31823009
Genetic and immunopathological analysis of CHCHD10 in Australian amyotrophic lateral sclerosis and frontotemporal dementia and transgenic TDP-43 mice., PMID:31690696
The large repertoire of conifer NLR resistance genes includes drought responsive and highly diversified RNLs., PMID:31406137
Help wanted: helper NLRs and plant immune responses., PMID:31063902
Multivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth., PMID:30995994
Proteomic profiling data of HEK293 proteins bound to human recombinant renalases-1 and -2., PMID:30456273
Genome-Wide Methylation Analysis Identifies NOX4 and KDM5A as Key Regulators in Inhibiting Breast Cancer Cell Proliferation by Ginsenoside Rg3., PMID:30149757
Genome-Wide Identification of NBS-Encoding Resistance Genes in Sunflower (Helianthus annuus L.)., PMID:30061549
Prediction of type 1 diabetes using a genetic risk model in the Diabetes Autoimmunity Study in the Young., PMID:28695611
Distinct Patterns of Gene Gain and Loss: Diverse Evolutionary Modes of NBS-Encoding Genes in Three Solanaceae Crop Species., PMID:28364035
Comparative Analysis of Renin-Angiotensin System (RAS)-Related Gene Expression Between Hypertensive and Normotensive Rats., PMID:28138124
Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy., PMID:27445147
For research use only. Not for human or drug use.
