Catalog No.
YHJ02701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu30-His317
Predicted molecular weight
35.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q5T4F7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FRP-1b, SFRP5, Secreted apoptosis-related protein 3, FRP1B, Frizzled-related protein 1b, SARP-3, sFRP-5, SARP3, Secreted frizzled-related protein 5
sFRP5 ameliorates atherosclerosis by suppressing the JNK/TLR9 pathway in macrophages., PMID:40409587
Evolutionary and Structural Assessment of the Human Secreted Frizzled-Related Protein (SFRP) Family., PMID:40372458
Expression and Effects of FUS/Sfrp5/Wnt5 in Atherosclerosis Development., PMID:40340876
UHRF1-mediated epigenetic reprogramming regulates glycolysis to promote progression of B-cell acute lymphoblastic leukemia., PMID:40301374
Association of Serum Secreted Frizzled-Related Protein 5 Levels With Coronary Artery Disease., PMID:40213711
The Relationship Between Serum SFRP5, ApoA-I, HDL3-C Level and In-Stent Restenosis After PCI in Acute Myocardial Infarction and the Combined Predictive Value., PMID:40056066
The mesenteric adipokine SFRP5 alleviated intestinal epithelial apoptosis improving barrier dysfunction in Crohn's disease., PMID:39759008
Expression, prognosis, immunological infiltration, and DNA methylation of members of the SFRP gene family in colorectal cancer: a comparative bioinformatic and experimental analysis., PMID:39729237
Chondroprotective functions of neutrophil-derived extracellular vesicles by promoting the production of secreted frizzled-related protein 5 in cartilage., PMID:39604981
SP1-mediated transcriptional repression of SFRP5 is correlated with cardiac fibroblast activation and atrial myocyte apoptosis in the development of atrial fibrillation., PMID:39536929
Increased susceptibility to diet-induced obesity in female mice impairs ovarian steroidogenesis: The role of elevated leptin signalling on nodal activity inhibition in theca cells., PMID:39536822
Serum adiponectin level is negatively related to insulin resistance in women with polycystic ovary syndrome., PMID:39475750
C6 and KLRG2 are pyroptosis subtype-related prognostic biomarkers and correlated with tumor-infiltrating lymphocytes in lung adenocarcinoma., PMID:39438534
The Role of Secreted Frizzled-Related Protein 5 (Sfrp5) in Overweight and Obesity in Childhood and Adolescence., PMID:39339733
Brainstem transcriptomic changes in male Wistar rats after acute stress, comparing the use of duplex specific nuclease (DSN)., PMID:39300279
Prognostic significance of serum secreted frizzled-related protein 5 in patients with acute aortic dissection., PMID:39253195
Expression Pattern of PDE4B, PDE4D, and SFRP5 Markers in Colorectal Cancer., PMID:39202484
Secreted Frizzled-Related Protein 5 Mediates Wnt5a Expression in Microcystin-Leucine-Arginine-Induced Liver Lipid Metabolism Disorder in Mice., PMID:39198250
Role of SFRP5 in Non-Small Cell Lung Cancer and Its Correlation with SUV of 18F-FDG PET-CT., PMID:39074839
Diagnostic and prognostic significance of circulating secreted frizzled-related protein 5 in colorectal cancer., PMID:38872420
Role of secreted frizzled-related protein 5 in granulosa cells of hu sheep ovaries., PMID:38805996
Secreted frizzled-related protein 5 overexpression reverses oxLDL-induced lipid accumulation in human vascular smooth muscle cells., PMID:38714325
Bone canonical Wnt signaling is downregulated in type 2 diabetes and associates with higher advanced glycation end-products (AGEs) content and reduced bone strength., PMID:38598270
Secreted frizzled-related protein 5 protects against renal fibrosis by inhibiting Wnt/β-catenin pathway., PMID:38584843
Transcriptomic Analysis Reveals Intrinsic Abnormalities in Endometrial Polyps., PMID:38473810
Silencing of forkhead box C1 reduces nasal epithelial barrier damage in mice with allergic rhinitis via epigenetically upregulating secreted frizzled-related protein 5., PMID:38422887
SFRP5 Partially Inhibits the Proliferation and Migration of Airway Smooth Muscle Cells in Children with Asthma by Regulating the Wnt/β-Catenin Signaling Pathway., PMID:38409837
Identification of candidate regulatory genes for intramuscular fatty acid composition in pigs by transcriptome analysis., PMID:38347496
Efficacy of Yisui granule on myelodysplastic syndromes in SKM-1 mouse xenograft model through suppressing Wnt/β-catenin signaling pathway., PMID:38213242
Research Progress on the Mechanism of the SFRP-Mediated Wnt Signalling Pathway Involved in Bone Metabolism in Osteoporosis., PMID:38194214
Expression of secreted frizzled-related proteins in acute aortic dissection patients and the effects on prognosis., PMID:38188253
Concentration of Secreted Frizzled-Related Proteins (SFRPs) in Non-Small Cell Lung Carcinoma Subtypes-A Preliminary Study., PMID:37999144
The synergy of serum SFRP5 levels and the TyG index in predicting coronary artery disease and prognosing major adverse cardiovascular events., PMID:37957661
Role and mechanism of PVN-sympathetic-adipose circuit in depression and insulin resistance induced by chronic stress., PMID:37870400
Transcriptional expression, prognostic value and immune infiltration of SFRP family in colorectal cancer: a study based on comprehensive bioinformatics and in vitro analyses., PMID:37701102
Secreted frizzled-related protein 5: A promising therapeutic target for metabolic diseases via regulation of Wnt signaling., PMID:37549604
Cumulative effects of exercise training and consumption of propolis on managing diabetic dyslipidemia in adult women: a single-blind, randomized, controlled trial with pre-post-intervention assessments., PMID:37542207
Association of Circulating Plasma Secreted Frizzled-Related Protein 5 (Sfrp5) Levels with Cardiac Function., PMID:37504530
Effect of glucagon-like peptide-1 receptor agonist on insulin secretion index and serum Wnt5a protein in patients with new-onset type 2 diabetes mellitus., PMID:37255814
TFAP2C inhibits cell autophagy to alleviate myocardial ischemia/reperfusion injury by regulating miR-23a-5p/SFRP5/Wnt5a axis., PMID:37191968
Pinostrobin induces acute leukemia cell apoptosis via the regulation of miR-410-5p and SFRP5., PMID:37164308
Leptin/SFRP5 ratio as a potential predictor of postpartum weight retention. A prospective pilot study., PMID:37042328
Extracellular matrix-based gene signature for predicting prognosis in colon cancer and immune microenvironment., PMID:36915600
Secreted Frizzled Related Protein 5 (SFRP5) Serum Levels Are Decreased in Critical Illness and Sepsis and Are Associated with Short-Term Mortality., PMID:36830849
Frizzled receptors and SFRP5 in lipid metabolism: Current findings and potential applications., PMID:36631199
Human epicardial adipose tissue inflammation correlates with coronary artery disease., PMID:36603481
Transgenerational bone toxicity in F3 medaka (Oryzias latipes) induced by ancestral benzo[a]pyrene exposure: Cellular and transcriptomic insights., PMID:36522066
Wingless-related integration site (WNT) signaling is activated during the inflammatory response upon cardiac surgery: A translational study., PMID:36440011
Intestinal precursors avoid being misinduced to liver cells by activating Cdx-Wnt inhibition cascade., PMID:36396123
Increased Secreted Frizzled-Related Protein 5 mRNA Expression in the Adipose Tissue of Women with Nonalcoholic Fatty Liver Disease Associated with Obesity., PMID:36077270
For research use only. Not for human or drug use.
