Catalog No.
YHJ01501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser457-Gly707
Predicted molecular weight
29.12 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q5GFL6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Colon cancer secreted protein 2, AMACO, CCSP-2, VWA2, von Willebrand factor A domain-containing protein 2, A domain-containing protein similar to matrilin and collagen
Finding Potential Drug Targets for Pre-Eclampsia Using Mendelian Randomisation and Colocalisation Analysis., PMID:40028697
Multi-Omics Approaches Uncovered Critical mRNA-miRNA-lncRNA Networks Regulating Multiple Birth Traits in Goat Ovaries., PMID:39596531
The integrated molecular and histological analysis defines subtypes of esophageal squamous cell carcinoma., PMID:39419971
VWA2 protein molecular mechanism predicts colorectal cancer: Promoting cell invasion and migration by inhibiting NK cell activation., PMID:39245093
The Fraser Complex Proteins (Frem1, Frem2, and Fras1) Can Form Anchoring Cords in the Absence of AMACO at the Dermal-Epidermal Junction of Mouse Skin., PMID:37047755
Construction of mouse cochlin mutants with different GAG-binding specificities and their use for immunohistochemistry., PMID:36511224
Anchoring Cords: A Distinct Suprastructure in the Developing Skin., PMID:35613627
Biomolecular imaging of colorectal tumor lesions using a FITC-labeled scFv-Cκ fragment antibody., PMID:34433835
The Importance of Sex in the Discovery of Colorectal Cancer Prognostic Biomarkers., PMID:33572952
Contribution of homozygous and compound heterozygous missense mutations in VWA2 to Alzheimer's disease., PMID:33023779
Structure and interactions of the archaeal motility repression module ArnA-ArnB that modulates archaellum gene expression in Sulfolobus acidocaldarius., PMID:30902813
Epigenetic and transcriptional dysregulation of VWA2 associated with a MYC-driven oncogenic program in colorectal cancer., PMID:30038405
A homozygous missense variant in VWA2, encoding an interactor of the Fraser-complex, in a patient with vesicoureteral reflux., PMID:29351342
Molecular Imaging of Colorectal Tumors by Targeting Colon Cancer Secreted Protein-2 (CCSP-2)., PMID:28886423
A novel Dock8 gene mutation confers diabetogenic susceptibility in the LEW.1AR1/Ztm-iddm rat, an animal model of human type 1 diabetes., PMID:26363782
A new component of the Fraser complex., PMID:24732331
AMACO is a component of the basement membrane-associated Fraser complex., PMID:24232570
B cells, dendritic cells, and macrophages are required to induce an autoreactive CD4 helper T cell response in experimental epidermolysis bullosa acquisita., PMID:23960233
A rapid cloning method employing orthogonal end protection., PMID:22685543
A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13., PMID:21385852
Expression of the AMACO (VWA2 protein) ortholog in zebrafish., PMID:19861176
Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment., PMID:19651211
Extensive contacts between ADAMTS13 exosites and von Willebrand factor domain A2 contribute to substrate specificity., PMID:18492952
O-glucosylation and O-fucosylation occur together in close proximity on the first epidermal growth factor repeat of AMACO (VWA2 protein)., PMID:18434322
IDDM17: polymorphisms in the AMACO gene are associated with dominant protection against type 1A diabetes in a Bedouin Arab family., PMID:15699509
Colon cancer secreted protein-2 (CCSP-2), a novel candidate serological marker of colon neoplasia., PMID:15580307
Identification and characterization of AMACO, a new member of the von Willebrand factor A-like domain protein superfamily with a regulated expression in the kidney., PMID:14506275
For research use only. Not for human or drug use.
