Catalog No.
YHH37101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu47-Gly296
Predicted molecular weight
30.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16787
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Laminin-7 subunit alpha, Laminin-5 subunit alpha, Kalinin subunit alpha, E170, Epiligrin subunit alpha, Nicein subunit alpha, Laminin subunit alpha-3, LAMA3, Epiligrin 170 kDa subunit, Laminin-6 subunit alpha, LAMNA, laminin-5, laminin-332, epiligrin, kalinin, nicein, laminin-6, laminin-311, K-laminin, laminin-7, laminin-321, KS-laminin, laminin-13, laminin-323
miR-212-5p Regulates PM2.5-Induced Apoptosis by Targeting LAMC2 and LAMA3., PMID:40004224
Knockdown of LAMA3 enhances the sensitivity of colon cancer to oxaliplatin by regulating the Hippo-YAP pathway., PMID:39798821
Anti-Laminin β4 IgG Drives Tissue Damage in Anti-p200 Pemphigoid and Shows Interactions with Laminin α3 and γ1/2 Chains., PMID:39320300
TNF Induces Laminin-332-Encoding Genes in Endothelial Cells and Laminin-332 Promotes an Atherogenic Endothelial Phenotype., PMID:39201392
Molecular profiling of a cohort with epidermolysis bullosa in India: a single centre experience., PMID:39141798
Expression of the laminin genes family and its relationship to prognosis in pancreatic carcinoma., PMID:39039002
[Clinical and bioinformatics analysis of the relationship between LAMA3 DNA methylation expression and platinum resistance and prognosis in epithelial ovarian cancer]., PMID:38951081
Of LAMA3 and LAMB3: A novel gene therapy for epidermolysis bullosa., PMID:38631349
Correlation of laminin subunit alpha 3 expression in pancreatic ductal adenocarcinoma with tumor liver metastasis and survival., PMID:38452390
Lentiviral expression of wild-type LAMA3A restores cell adhesion in airway basal cells from children with epidermolysis bullosa., PMID:38429928
Laryngo-Onycho-Cutaneous Syndrome (LOCS)., PMID:38328664
LAMA3 Promotes Tumorigenesis of Oral Squamous Cell Carcinoma by METTL3-Mediated N6-Methyladenosine Modification., PMID:38305336
A missense mutation in Lama3 causes androgen alopecia., PMID:38012251
Heterozygous nonsense variants in laminin subunit 3α resulting in Ebstein's anomaly., PMID:37635785
A matrigel-free method for culture of pancreatic endocrine-like cells in defined protein-based hydrogels., PMID:36970620
Phenotypic variability in LAMA3-associated amelogenesis imperfecta., PMID:36326426
Novel variants in LAMA3 and COL7A1 and recurrent variant in KRT5 underlying epidermolysis bullosa in five Chinese families., PMID:35314946
LINC00936/microRNA-221-3p Regulates Tumor Progression in Ovarian Cancer by Interacting with LAMA3., PMID:35297352
[A pedigree study of laryngo-onycho-cutaneous syndrome with a novel mutation on LAMA3 gene]., PMID:35193344
Laminin Isoforms in Human Dental Pulp: Lymphatic Vessels Express Laminin-332, and Schwann Cell-Associated Laminin-211 Modulates CD163 Expression of M2-like Macrophages., PMID:34965967
Laminin alpha-3 and thrombospondin-1 differently regulate the survival and differentiation of hepatocytes and hepatic stem cells from neonatal mice., PMID:34956483
Gene expression profiling of laminin α3-blocked keratinocytes reveals an immune-independent mechanism of blistering., PMID:34796550
A case of mucous membrane pemphigoid with anti-laminin alpha 3 and beta 3 antibodies initially mimicking Stevens-Johnson syndrome., PMID:34196975
High expression of LAMA3/AC245041.2 gene pair associated with KRAS mutation and poor survival in pancreatic adenocarcinoma: a comprehensive TCGA analysis., PMID:34134622
LAMA3 DNA methylation and transcriptome changes associated with chemotherapy resistance in ovarian cancer., PMID:33992120
Identification and Computational Analysis of Novel Pathogenic Variants in Pakistani Families with Diverse Epidermolysis Bullosa Phenotypes., PMID:33921969
Atypical presentation of laryngo-onycho-cutaneous syndrome resulting from novel mutations in LAMA3A., PMID:33600006
Laminin‑332 mediates proliferation, apoptosis, invasion, migration and epithelial‑to‑mesenchymal transition in pancreatic ductal adenocarcinoma., PMID:33179081
Acute changes in nidogen-1 expression in the epidermal basement membrane of a 3-dimensional cultured human skin model after ultraviolet B irradiation., PMID:32920911
A novel mutation in LAMA3A gene in a child with laryngo-onycho-cutaneous syndrome from the Indian subcontinent., PMID:32719197
Human laminin α3 chain G1 domain is a receptor for plasminogen Kringle 5 on human endothelial cells by biological specificity technologies and molecular dynamic., PMID:32173023
Cervicovaginal fluid proteomic analysis to identify potential biomarkers for preterm birth., PMID:31758918
ENAM mutations and digenic inheritance., PMID:31478359
The Laminin Interactome: A Multifactorial Laminin-Binding Strategy by Nontypeable Haemophilus influenzae for Effective Adherence and Colonization., PMID:31034569
Downregulation of Extracellular Matrix and Cell Adhesion Molecules in Cumulus Cells of Infertile Polycystic Ovary Syndrome Women with and without Insulin Resistance., PMID:30507086
Targeted resequencing reveals genetic risks in patients with sporadic idiopathic pulmonary fibrosis., PMID:29920840
Aniridia-related keratopathy: Structural changes in naïve and transplanted corneal buttons., PMID:29889891
Novel autosomal recessive LAMA3 and PLEC variants underlie junctional epidermolysis bullosa generalized intermediate and epidermolysis bullosa simplex with muscular dystrophy in two consanguineous families., PMID:29797489
Substrate-mediated gene transduction of LAMA3 for promoting biological sealing between titanium surface and gingival epithelium., PMID:29096376
Natural history and clinical outcome of junctional epidermolysis bullosa generalized intermediate due to a LAMA3 mutation., PMID:29077994
Whole-Exome Sequencing Identifies Novel Variants for Tooth Agenesis., PMID:28813618
Identification of key genes associated with rheumatoid arthritis with bioinformatics approach., PMID:28767591
Comparison of gene expression profiles between dental pulp and periodontal ligament tissues in humans., PMID:28713908
Brassica rapa hairy root extracts promote skin depigmentation by modulating melanin production and distribution., PMID:28670794
Injury and defective regeneration of the epithelial basement membrane in corneal fibrosis: A paradigm for fibrosis in other organs?, PMID:28625845
EBM regeneration and changes in EBM component mRNA expression in stromal cells after corneal injury., PMID:28275314
Application of whole exome sequencing in elucidating the phenotype and genotype spectrum of junctional epidermolysis bullosa: A preliminary experience of a tertiary care centre in India., PMID:28087116
Carriers with functional null mutations in LAMA3 have localized enamel abnormalities due to haploinsufficiency., PMID:27827380
Genotype, Clinical Course, and Therapeutic Decision Making in 76 Infants with Severe Generalized Junctional Epidermolysis Bullosa., PMID:27375110
Targeted Disruption of the Lama3 Gene in Adult Mice Is Sufficient to Induce Skin Inflammation and Fibrosis., PMID:27729280
For research use only. Not for human or drug use.
