Catalog No.
YHH34901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asn176
Predicted molecular weight
45.14 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16676
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FREAC-4, FOXD1, FREAC4, Forkhead-related protein FKHL8, Forkhead-related transcription factor 4, FKHL8, Forkhead box protein D1
Tumor-associated macrophage-derived exosomes modulate the immunotherapeutic sensitivity of SHH-medulloblastoma by targeting m6A-modified FOXD1., PMID:40401803
Acupotomy Ameliorates KOA Related Chondrocyte Premature Senescence Through YAP/FOXD1 Pathway., PMID:40241815
Neural crest-associated gene FOXD1 induces an immunosuppressive microenvironment by regulating myeloid-derived suppressor cells in melanoma., PMID:40210238
Mesenchymal Meis2 controls whisker development independently from trigeminal sensory innervation., PMID:40183774
Expression of ENL YEATS domain tumor mutations in nephrogenic or stromal lineage impairs kidney development., PMID:40087269
Targeting ALG3/FOXD1/BNIP3 Axis Prevents Mitophagy and Gemcitabine Resistance of Nasopharyngeal Carcinoma., PMID:40083705
Platelet-Derived Growth Factor Promotes Glomerular Mesangial Cells Differentiation of Human Bone Marrow Hematopoietic Stem Cells - An In Vitro Study., PMID:40065657
ZEB2 signaling is essential for ureteral smooth muscle cell differentiation and maintenance., PMID:40060690
Identification of transcription factors associated with the disease-free survival of triple-negative breast cancer through weighted gene co-expression network analysis., PMID:39917004
Transcription factor FOXD1 and miRNA-204-5p play a major role in B4GALNT2 downregulation in colon cancer., PMID:39805916
Integrated singlecell and bulk RNA-seq analysis identifies a prognostic signature related to inflammation in colorectal cancer., PMID:39757274
Tcf21 as a founder transcription factor in specifying Foxd1 cells to the juxtaglomerular cell lineage., PMID:39589156
FOXD1 activates KIFC1 to modulate aerobic glycolysis and reinforce cisplatin resistance of breast cancer., PMID:39541848
Forkhead box D subfamily genes in colorectal cancer: potential biomarkers and therapeutic targets., PMID:39494294
A modified model of PANoptosisto identify prognosis and immunotherapy response in bladder cancer., PMID:39368544
Echinacoside inhibits hepatocellular carcinoma progression by targeting the miR-30c-5p/FOXD1/KLF12 axis., PMID:39269873
FoxD1 expression identifies a distinct subset of hepatic stellate cells involved in liver fibrosis., PMID:39226736
Spatial transcriptomic revealed intratumor heterogeneity and cancer stem cell enrichment in colorectal cancer metastasis., PMID:39159882
Waterpipe smoke condensate induces epithelial-mesenchymal transformation and promotes metastasis of oral cancer by FOXD1 expression., PMID:38692456
Long non-coding RNAFOXD1-AS1 modulated CTCs epithelial-mesenchymal transition and immune escape in hepatocellular carcinoma in vitro by sponging miR-615-3p., PMID:38517478
Integrative analysis with machine learning identifies diagnostic and prognostic signatures in neuroblastoma based on differentially DNA methylated enhancers between INSS stage 4 and 4S neuroblastoma., PMID:38512513
Early embryogenesis in CHDFIDD mouse model reveals facial clefts and altered cranial neurogenesis., PMID:38511331
Assessing the fate and contribution of Foxd1-expressing embryonic precursors and their progeny in palatal development, homeostasis and excisional repair., PMID:38424240
Integrative analysis of potential diagnostic markers and therapeutic targets for glomerulus-associated diabetic nephropathy based on cellular senescence., PMID:38390397
Single-cell analysis reveals the spatial-temporal expression of genes associated with esophageal malformations., PMID:38355689
Identification of the six-hormone secretion-related gene signature as a prognostic biomarker for colon adenocarcinoma., PMID:38143338
The TRIM21-FOXD1-BCL-2 axis underlies hyperglycaemic cell death and diabetic tissue damage., PMID:38092733
SUMOylation of RALY promotes vasculogenic mimicry in glioma cells via the FOXD1/DKK1 pathway., PMID:37906341
Stromal netrin 1 coordinates renal arteriogenesis and mural cell differentiation., PMID:37823339
Netrin 1 directs vascular patterning and maturity in the developing kidney., PMID:37818607
Hedgehog signalling in Foxd1+ embryonic kidney stromal progenitors controls nephron formation via Cxcl12 and Wnt5a., PMID:37772431
Dissecting multifunctional roles of forkhead box transcription factor D1 in cancers., PMID:37716516
miR-30e-5p-mediated FOXD1 promotes cell proliferation by blocking cellular senescence and apoptosis through p21/CDK2/Rb signaling in head and neck carcinoma., PMID:37563111
FOXD1 promotes chemotherapy resistance by enhancing cell stemness in colorectal cancer through β‑catenin nuclear localization., PMID:37203394
Genome-wide DNA methylation profiling after Ayurveda intervention to bronchial asthmatics identifies differential methylation in several transcription factors with immune process related function., PMID:37018893
Identification of transcription factors related to diabetic tubulointerstitial injury., PMID:36978091
Transcription factors: a potential therapeutic target in head and neck squamous cell carcinoma., PMID:36974620
Inactivation of Invs/Nphp2 in renal epithelial cells drives infantile nephronophthisis like phenotypes in mouse., PMID:36920028
BMSC-Derived Exosomes Carrying lncRNA-ZFAS1 Alleviate Pulmonary Ischemia/Reperfusion Injury by UPF1-Mediated mRNA Decay of FOXD1., PMID:36652050
A comprehensive analysis of the FOX family for predicting kidney renal clear cell carcinoma prognosis and the oncogenic role of FOXG1., PMID:36585925
Foxd1-dependent induction of a temporal retinal character is required for visual function., PMID:36520654
ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis., PMID:36445780
FOXD1 is required for 3D patterning of the kidney interstitial matrix., PMID:36335435
FOXD1-dependent RalA-ANXA2-Src complex promotes CTC formation in breast cancer., PMID:36229838
FOXD1-mTOR Signaling Pathway on Oral Squamous Cell Carcinoma and Its Inhibition by Rosemary Extract (Invitro-Study)., PMID:36172670
Foxc1 and Foxc2 are indispensable for the maintenance of nephron and stromal progenitors in the developing kidney., PMID:36073617
FOXD1 facilitates pancreatic cancer cell proliferation, invasion, and metastasis by regulating GLUT1-mediated aerobic glycolysis., PMID:36057597
USP21 promotes self-renewal and tumorigenicity of mesenchymal glioblastoma stem cells by deubiquitinating and stabilizing FOXD1., PMID:35974001
Stromal Transcription Factor 21 Regulates Development of the Renal Stroma via Interaction with Wnt/β-Catenin Signaling., PMID:35919523
Identification of Antitumor miR-30e-5p Controlled Genes; Diagnostic and Prognostic Biomarkers for Head and Neck Squamous Cell Carcinoma., PMID:35886008
For research use only. Not for human or drug use.
