Catalog No.
YHH34001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Met316
Predicted molecular weight
38.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16659
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in 50mM Tris, 150mM NaCl, pH 8.0, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
p97-MAPK, ERK3, PRKM6, Mitogen-activated protein kinase 6, MAP kinase isoform p97, MAPK 6, ERK-3, MAP kinase 6, Extracellular signal-regulated kinase 3, MAPK6
SERPINA1 methylation as a novel diagnostic marker for early-stage papillary thyroid carcinoma via MAPK6-AKT/mTOR pathway., PMID:40442821
Anticancer Effects of MAPK6 siRNA-Loaded PLGA Nanoparticles in the Treatment of Breast Cancer., PMID:39823246
Disturbed shear stress promotes atherosclerosis through TRIM21-regulated MAPK6 degradation and consequent endothelial inflammation., PMID:39763069
ACS2 and ACS6, especially ACS2 is involved in MPK6 evoked production of ethylene under Cd stress, which exacerbated Cd toxicity in Arabidopsis thaliana., PMID:39672386
Transcriptome analysis of the cytokine storm-related genes among the subtypes of idiopathic multicentric Castleman disease., PMID:39462545
RMD and Its Suppressor MAPK6 Control Root Circumnutation and Obstacle Avoidance via BR Signaling., PMID:39408870
Atypical MAPKs in cancer., PMID:39348153
Comparison of the gene expression profiles of endometrial and trophoblastic cells in women with recurrent miscarriage: A bioinformatics approach., PMID:39205919
The circ_0003928/miR-31-5p/MAPK6 cascade affects high glucose-induced inflammatory response, fibrosis and oxidative stress in HK-2 cells., PMID:38964515
ERK3 is involved in regulating cardiac fibroblast function., PMID:38872461
Characterization of putative calcium-dependent protein kinase-1 (TaCPK-1) gene: hubs in signalling and tolerance network of wheat under terminal heat., PMID:38725866
miR-144 affects the immune response and activation of inflammatory responses in Cynoglossus semilaevis by regulating the expression of CsMAPK6., PMID:38670413
Bioinformatic Identification and Expression Analyses of the MAPK-MAP4K Gene Family Reveal a Putative Functional MAP4K10-MAP3K7/8-MAP2K1/11-MAPK3/6 Cascade in Wheat (Triticum aestivum L.)., PMID:38611471
Long non-coding RNA DANCR increases spinal cord neuron apoptosis and inflammation of spinal cord injury by mediating the microRNA-146a-5p/MAPK6 axis., PMID:38551688
Evaluation of BG, NPR1, and PAL in cotton plants through Virus Induced gene silencing reveals their role in whitefly stress., PMID:38360122
Melatonin-mediated regulation of autophagy is independent of ABA under drought stress in sensitive variety of Gossypium hirsutum L., PMID:38346368
The WRKY17-WRKY50 complex modulates anthocyanin biosynthesis to improve drought tolerance in apple., PMID:38142750
Triazolo[4,5-d]pyrimidin-5-amines based ERK3 inhibitors fail to demonstrate selective effects on adipocyte function., PMID:37992885
Phosphoproteomics Reveal New Candidates in Abnormal Spermatogenesis of Pseudomales in Cynoglossus semilaevis., PMID:37511189
CircGAB1 Facilitates Podocyte Injury Through Sponging miR-346 and Activating MAPK6 in Diabetic Nephropathy., PMID:37440116
Deoxythymidylate kinase (DTYMK) participates in cell cycle arrest to promote pancreatic adenocarcinoma progression regulated by miR-491-5p through TP53 and is associated with tumor immune infiltration., PMID:37435228
Systemic Diclofenac Sodium Reduces Postoperative rhBMP-2 Induced Neuroinflammation: A Rodent Model Study., PMID:37326447
Increased methylation of ZNF671 suppresses tumor progression by promoting MAPK6 transcription in laryngeal carcinoma., PMID:37215982
Viral synergism suppresses R gene-mediated resistance by impairing downstream defense mechanisms in soybean., PMID:37099452
ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization., PMID:37057894
Altered Cathepsin B Expression as a Diagnostic Marker of Skeletal Muscle Insulin Resistance in Type 2 Diabetes., PMID:37026167
HNF4G increases cisplatin resistance in lung adenocarcinoma via the MAPK6/Akt pathway., PMID:36923501
CircDNAJC11 interacts with TAF15 to promote breast cancer progression via enhancing MAPK6 expression and activating the MAPK signaling pathway., PMID:36895010
Uncovering the genetic links of diabetic erectile dysfunction and chronic prostatitis/chronic pelvic pain syndrome., PMID:36846330
Comprehensive analysis of the PTPN13 expression and its clinical implication in breast cancer., PMID:36812232
Dimethylthiourea Alleviates Drought Stress by Suppressing Hydrogen Peroxide-Dependent Abscisic Acid-Mediated Oxidative Responses in an Antagonistic Interaction with Salicylic Acid in Brassica napus Leaves., PMID:36421468
miR-128-3p inhibits the inflammation by targeting MAPK6 in penicillin-induced astrocytes., PMID:36250437
Phosphoproteomics of extracellular vesicles integrated with multiomics analysis reveals novel kinase networks for lung cancer., PMID:36148632
The immunity priming effect of the Arabidopsis phyllosphere resident yeast Protomyces arabidopsidicola strain C29., PMID:36118213
Docking simulation and ADMET prediction based investigation on the phytochemical constituents of Noni (Morinda citrifolia) fruit as a potential anticancer drug., PMID:36034317
Targeting ERK3/MK5 complex for treatment of obesity and diabetes., PMID:35523049
LncRNA LINC00649 recruits TAF15 and enhances MAPK6 expression to promote the development of lung squamous cell carcinoma via activating MAPK signaling pathway., PMID:35228660
ERK3-MK5 signaling regulates myogenic differentiation and muscle regeneration by promoting FoxO3 degradation., PMID:35141958
Exosomes from miR-374a-5p-modified mesenchymal stem cells inhibit the progression of renal fibrosis by regulating MAPK6/MK5/YAP axis., PMID:35137672
Identification of Crucial Hub Genes and Differential T Cell Infiltration in Idiopathic Pulmonary Arterial Hypertension Using Bioinformatics Strategies., PMID:35127829
Rab31 promotes the invasion and metastasis of cervical cancer cells by inhibiting MAPK6 degradation., PMID:34975321
Identification of Potential Osteoporosis miRNA Biomarkers Using Bioinformatics Approaches., PMID:34777562
MAPK6-AKT signaling promotes tumor growth and resistance to mTOR kinase blockade., PMID:34767444
Pharmacoinformatics-based investigation of bioactive compounds of Rasam (South Indian recipe) against human cancer., PMID:34728718
Conditional ERK3 overexpression cooperates with PTEN deletion to promote lung adenocarcinoma formation in mice., PMID:34719109
Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism., PMID:34642330
Aberrant activation of m6A demethylase FTO renders HIF2αlow/- clear cell renal cell carcinoma sensitive to BRD9 inhibitors., PMID:34586831
WRKY53 integrates classic brassinosteroid signaling and the mitogen-activated protein kinase pathway to regulate rice architecture and seed size., PMID:34003966
miR‑653‑5p suppresses the growth and migration of breast cancer cells by targeting MAPK6., PMID:33495824
LncRNA GAS6-AS2 promotes non-small-cell lung cancer cell proliferation via regulating miR-144-3p/ MAPK6 axis., PMID:33459113
For research use only. Not for human or drug use.
