Catalog No.
YHH32901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly3-Ser134
Predicted molecular weight
16.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16643
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
D0S117E, DBN1, Developmentally-regulated brain protein, Drebrin
Mechanisms underlying sustained resilience against anorexia nervosa from sub-anesthetic ketamine: A review and new research based on electron microscopic analyses of synapses using a mouse model., PMID:40403996
Cx45 regulation by kinases and impact of expression in heart failure., PMID:40280467
Dynamic Interchange of Local Residue-Residue Interactions in the Largely Extended Single Alpha-Helix in Drebrin., PMID:40192062
MAZ-induced lncRNA H19 regulates proliferation and differentiation of porcine skeletal muscle satellite cells via sponge miR-935/miR-296-5p and the p38 MAPK pathway., PMID:40164245
Molecular switch of the dendrite-to-spine transport of TDP-43/FMRP-bound neuronal mRNAs and its impairment in ASD., PMID:39815169
Inhibition of IRAP Enhances the Expression of Pro-Cognitive Markers Drebrin and MAP2 in Rat Primary Neuronal Cells., PMID:39596085
The actin cytoskeleton is important for pseudorabies virus infection., PMID:39255726
Junctional Adhesion Molecule (JAM)-C recruitment of Pard3 and drebrin to cell contacts initiates neuron-glia recognition and layer-specific cell sorting in developing cerebella., PMID:38585827
Targeting the cytoskeleton as a therapeutic approach to substance use disorders., PMID:38499081
A lack of drebrin causes olfactory impairment., PMID:38376048
Insights into early pathogenesis of sporadic Alzheimer's disease: role of oxidative stress and loss of synaptic proteins., PMID:38260013
Sorl1 knockout inhibits expression of brain-derived neurotrophic factor: involvement in the development of late-onset Alzheimer's disease., PMID:38051905
Super-resolution imaging reveals the relationship between CaMKIIβ and drebrin within dendritic spines., PMID:37659612
Effects of 660-nm LED photobiomodulation on drebrin expression pattern and astrocyte migration., PMID:37069238
A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer's disease exacerbated with high fat diet., PMID:36895036
The well-developed actin cytoskeleton and Cthrc1 expression by actin-binding protein drebrin in myofibroblasts promote cardiac and hepatic fibrosis., PMID:36690273
Chinese herbal compound Jinsiwei improves synaptic plasticity in mice with sporadic Alzheimer's disease induced by streptozotocin., PMID:36639998
Clinical Implications and Molecular Characterization of Drebrin-Positive, Tumor-Infiltrating Exhausted T Cells in Lung Cancer., PMID:36430217
Identification of some calcium binding proteins and neural cell markers in rat testis and epididymis during postnatal development., PMID:36376057
Phldb2 is essential for regulating hippocampal dendritic spine morphology through drebrin in an adult-type isoform-specific manner., PMID:36162735
Individual differences in the positive outcome from adolescent ketamine treatment in a female mouse model of anorexia nervosa involve drebrin A at excitatory synapses of the medial prefrontal cortex., PMID:36121749
Neuronal paxillin and drebrin mediate BDNF-induced force transduction and growth cone turning in a soft-tissue-like environment., PMID:35977504
Cranial irradiation induces cognitive decline associated with altered dendritic spine morphology in the young rat hippocampus., PMID:35962792
SARM1 Suppresses Axon Branching Through Attenuation of Axonal Cytoskeletal Dynamics., PMID:35264929
Microscopic Temperature Control Reveals Cooperative Regulation of Actin-Myosin Interaction by Drebrin E., PMID:34751025
Postsynaptic structure formation of human iPS cell-derived neurons takes longer than presynaptic formation during neural differentiation in vitro., PMID:34629097
The drebrin/EB3 pathway regulates cytoskeletal dynamics to drive neuritogenesis in embryonic cortical neurons., PMID:34478582
Drebrin attenuates atherosclerosis by limiting smooth muscle cell transdifferentiation., PMID:33914863
The actin binding protein drebrin helps to protect against the development of seizure-like events in the entorhinal cortex., PMID:33883605
Herpes Simplex Virus Type 1 Neuronal Infection Triggers the Disassembly of Key Structural Components of Dendritic Spines., PMID:33708072
Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking., PMID:33674568
Alteration of CYP2E1, DBN1, DNMT1, miRNA-335, miRNA-21, c-Fos and Cox-2 gene expression in prefrontal cortex of rats' offspring submitted to prenatal ethanol exposure during their neurodevelopment and the preventive role of nancocurcumin administration: A histological, ultrastructural and molecular study., PMID:33657396
Preservation of dendritic spine morphology and postsynaptic signaling markers after treatment with solid lipid curcumin particles in the 5xFAD mouse model of Alzheimer's amyloidosis., PMID:33557949
Drebrin regulates cytoskeleton dynamics in migrating neurons through interaction with CXCR4., PMID:33414275
Genetic Knockout of the Serotonin Reuptake Transporter Results in the Reduction of Dendritic Spines in In vitro Rat Cortical Neuronal Culture., PMID:33403594
Long Non-coding RNA H19 Regulates Porcine Satellite Cell Differentiation Through miR-140-5p/SOX4 and DBN1., PMID:33324629
Biased localization of actin binding proteins by actin filament conformation., PMID:33239610
The actin binding protein α-actinin-2 expression is associated with dendritic spine plasticity and migrating granule cells in the rat dentate gyrus following pilocarpine-induced seizures., PMID:33098872
Exploring Potential Proteomic Biomarkers for Prognosis of Infective Endocarditis through Profiled Autoantibodies by an Immunomics Protein Array Technique., PMID:32990583
Drebrin expression patterns in patients with refractory temporal lobe epilepsy and hippocampal sclerosis., PMID:32662890
Integrated Analysis of Key Differentially Expressed Genes Identifies DBN1 as a Predictive Marker of Response to Endocrine Therapy in Luminal Breast Cancer., PMID:32545448
Potential Neurodevelopmental Effects of Pediatric Intensive Care Sedation and Analgesia: Repetitive Benzodiazepine and Opioid Exposure Alters Expression of Glial and Synaptic Proteins in Juvenile Rats., PMID:32426747
Progranulin/EphA2 axis: A novel oncogenic mechanism in bladder cancer., PMID:32417448
Dimerization of Human Drebrin-like Protein Governs Its Biological Activity., PMID:32282191
TFAP2A Induced ITPKA Serves as an Oncogene and Interacts with DBN1 in Lung Adenocarcinoma., PMID:32015686
Testosterone modulates structural synaptic plasticity of primary cultured hippocampal neurons through ERK - CREB signalling pathways., PMID:31805308
X-irradiation of developing hippocampal neurons causes changes in neuron population phenotypes, dendritic morphology and synaptic protein expression in surviving neurons at maturity., PMID:31711782
Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes., PMID:31586053
A novel role for the actin-binding protein drebrin in regulating opiate addiction., PMID:31515501
Post-mortem Characterisation of a Case With an ACTG1 Variant, Agenesis of the Corpus Callosum and Neuronal Heterotopia., PMID:31231230
For research use only. Not for human or drug use.
