Catalog No.
YHH15901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu85-His332
Predicted molecular weight
29.17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15653
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IKBB, IkB-beta, TRIP9, TRIP-9, IkappaBbeta, I-kappa-B-beta, IkB-B, NFKBIB, NF-kappa-B inhibitor beta, TR-interacting protein 9, NF-kappa-BIB, Thyroid receptor-interacting protein 9
Dipeptidyl peptidase 9 (DPP9) depletion from hepatocytes in experimental primary liver cancer., PMID:40187163
Discovering new hub genes of dilated cardiomyopathy., PMID:40074718
Transcriptome analysis of the cytokine storm-related genes among the subtypes of idiopathic multicentric Castleman disease., PMID:39462545
Selective Hypoxia-Sensitive Oxomer Formation by FIH Prevents Binding of the NF-κB Inhibitor IκBβ to NF-κB Subunits., PMID:38644795
Differential Gene Expression Profiles in Inflammatory Bowel Disease Patients from Kurdistan, Iraq., PMID:38434468
Lost and Found: The Family of NF-κB Inhibitors Is Larger than Assumed in Salmonid Fish., PMID:37373375
New insights into the mechanism of ammonia toxicity: Focus on Cactus., PMID:36508831
Absence of IκBβ/NFκB signaling does not attenuate acetaminophen-induced hepatic injury., PMID:36426684
Differential expression of genes regulated by the glucocorticoid receptor pathway in patients with pulmonary tuberculosis., PMID:35526591
Establishment of the TBX-code reveals aberrantly activated T-box gene TBX3 in Hodgkin lymphoma., PMID:34807923
APAP-Induced IκBβ/NFκB Signaling Drives Hepatic Il6 Expression and Associated Sinusoidal Dilation., PMID:34726736
The Acute Hepatic NF-κB-Mediated Proinflammatory Response to Endotoxemia Is Attenuated in Intrauterine Growth-Restricted Newborn Mice., PMID:34539638
Potential biomarkers: differentially expressed proteins of the extrinsic coagulation pathway in plasma samples from patients with depression., PMID:34488523
Micro RNAs 26b, 20a inversely correlate with GSK-3 β/NF-κB/NLRP-3 pathway to highlight the additive promising effects of atorvastatin and quercetin in experimental induced arthritis., PMID:34426107
Inhibition of soluble epoxide hydrolase alleviates insulin resistance and hypertension via downregulation of SGLT2 in the mouse kidney., PMID:33864813
Syntaxin 4 Mediates NF-κB Signaling and Chemokine Ligand Expression via Specific Interaction With IκBβ., PMID:33526588
Febuxostat Attenuates the Induction of Vascular Cell Adhesion Protein 1 by TNF-α in Human Umbilical Vein Endothelial Cells., PMID:33176323
Long noncoding RNA LINC01578 drives colon cancer metastasis through a positive feedback loop with the NF-κB/YY1 axis., PMID:33040438
IL-1α released from oral epithelial cells upon candidalysin exposure initiates an early innate epithelial response., PMID:33038250
A Novel Mechanism for NF-κB-activation via IκB-aggregation: Implications for Hepatic Mallory-Denk-Body Induced Inflammation., PMID:32912968
Anti-inflammatory and anti-proliferative action of adiponectin mediated by insulin signaling cascade in human vascular smooth muscle cells., PMID:32789574
Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway., PMID:32685465
Control of Murine Primordial Follicle Growth Activation by IκB/NFκB Signaling., PMID:32542534
Gold Nanocomplex Strongly Modulates the PI3K/Akt Pathway and Other Pathways in MCF-7 Breast Cancer Cell Line., PMID:32397063
CpG-ODN-mediated TLR9 innate immune signalling and calcium dyshomeostasis converge on the NFκB inhibitory protein IκBβ to drive IL1α and IL1β expression., PMID:32064589
The NF-κB regulator IκBβ exhibits different molecular interactivity and phosphorylation status from IκBα in an IKK2-catalysed reaction., PMID:32017069
Mechanism and implications of morphogen shuttling: Lessons learned from dorsal and Cactus in Drosophila., PMID:31987808
Apigenin Prevent Abdominal Aortic Aneurysms Formation by Inhibiting the NF-κB Signaling Pathway., PMID:31821190
Short-Term Microgravity Influences Cell Adhesion in Human Breast Cancer Cells., PMID:31731625
Silencing of SPARC represses heterotopic ossification via inhibition of the MAPK signaling pathway., PMID:31548362
miR-20a regulates inflammatory in osteoarthritis by targeting the IκBβ and regulates NK-κB signaling pathway activation., PMID:31451219
Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors., PMID:31363162
Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy., PMID:30994864
Toll-Like Receptor and miRNA-let-7e Expression Alter the Inflammatory Response in Leishmania amazonensis-Infected Macrophages., PMID:30555476
Changes in mRNA expression of members of TGFB1-associated pathways in human leukocytes during EBV infection., PMID:30465450
Insights into the genomic landscape of MYD88 wild-type Waldenström macroglobulinemia., PMID:30401751
Effect of PEA-OXA on neuropathic pain and functional recovery after sciatic nerve crush., PMID:30217164
Really interesting new gene finger protein 121 is a tumor suppressor of renal cell carcinoma., PMID:30149063
Role of Thrombospondin-1 and Nuclear Factor-κB Signaling Pathways in Antiangiogenesis of Infantile Hemangioma., PMID:30148773
Effect of selected strains of lactobacilli on the antioxidant and anti-inflammatory properties of sourdough., PMID:30036730
Statistical Framework for Uncertainty Quantification in Computational Molecular Modeling., PMID:29989988
Mechanism of vaccinia viral protein B14-mediated inhibition of IκB kinase β activation., PMID:29748387
Changes of KEAP1/NRF2 and IKB/NF-κB Expression Levels Induced by Cell-Free DNA in Different Cell Types., PMID:29743966
Protection by mTOR Inhibition on Zymosan-Induced Systemic Inflammatory Response and Oxidative/Nitrosative Stress: Contribution of mTOR/MEK1/ERK1/2/IKKβ/IκB-α/NF-κB Signalling Pathway., PMID:29110153
Inhibition of IκBβ/NFκB signaling prevents LPS-induced IL1β expression without increasing apoptosis in the developing mouse lung., PMID:28753596
Hypothalamic stem cells control ageing speed partly through exosomal miRNAs., PMID:28746310
Cinnamon extracts exert intrapancreatic cytoprotection against streptozotocin in vivo., PMID:28694207
Systematic review and meta-analysis: pharmacogenetics of anti-TNF treatment response in rheumatoid arthritis., PMID:28607508
Succinamide derivatives of melampomagnolide B and their anti-cancer activities., PMID:28545815
Upregulation of miRNA-4776 in Influenza Virus Infected Bronchial Epithelial Cells Is Associated with Downregulation of NFKBIB and Increased Viral Survival., PMID:28448456