Catalog No.
YHH13801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser485-Asn683
Predicted molecular weight
24.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q155Q3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KIAA1735, DIXDC1, Dixin, CCD1, DIX domain-containing protein 1, Coiled-coil protein DIX1, Coiled-coil-DIX1
Screening of novel biomarkers for breast cancer based on WGCNA and multiple machine learning algorithms., PMID:37434679
Smoking and tetramer tryptase accelerate intervertebral disc degeneration by inducing METTL14-mediated DIXDC1 m6 modification., PMID:37340635
Identification of candidate genes for nicotine withdrawal in C57BL/6J × DBA/2J recombinant inbred mice., PMID:36781202
DIX domain containing 1 (DIXDC1) modulates VEGFR2 level in vasculatures to regulate embryonic and postnatal retina angiogenesis., PMID:35144597
Circular RNA circ_0000423 promotes gastric cancer cell proliferation, migration and invasion via the microR-582-3p/Disheveled-Axin domain containing 1 axis., PMID:34898351
Identification of Novel Serological Autoantibodies in Takayasu Arteritis Patients Using HuProt Arrays., PMID:33545363
Proteomic Analysis Reveals Autism-Associated Gene DIXDC1 Regulates Proteins Associated with Mitochondrial Organization and Function., PMID:33337894
Comprehensive characterization of driver genes in diffuse large B cell lymphoma., PMID:32565964
LncRNA SNHG20 enhances the progression of oral squamous cell carcinoma by regulating the miR-29a/DIXDC1/Wnt regulatory axis., PMID:32495922
Nuclear accumulation of pyruvate kinase M2 promotes liver regeneration via activation of signal transducer and activator of transcription 3., PMID:32198052
Hepatitis B Virus-Encoded MicroRNA (HBV-miR-3) Regulates Host Gene PPM1A Related to Hepatocellular Carcinoma., PMID:31686644
DIXDC1 promotes the growth of acute myeloid leukemia cells by upregulating the Wnt/β-catenin signaling pathway., PMID:30257373
DIXDC1 prevents oxygen-glucose deprivation/reoxygenation-induced injury in hippocampal neurons in vitro by promoting Wnt/β-catenin signaling., PMID:30229845
Suppression of Disheveled-Axin Domain Containing 1 (DIXDC1) by MicroRNA-186 Inhibits the Proliferation and Invasion of Retinoblastoma Cells., PMID:29264763
Interplay between FMRP and lncRNA TUG1 regulates axonal development through mediating SnoN-Ccd1 pathway., PMID:29211876
MicroRNA-154 Inhibits the Growth and Invasion of Gastric Cancer Cells by Targeting DIXDC1/WNT Signaling., PMID:28800791
Structural basis for Ccd1 auto-inhibition in the Wnt pathway through homomerization of the DIX domain., PMID:28798413
MicroRNA-539 inhibits glioma cell proliferation and invasion by targeting DIXDC1., PMID:28704799
Inhibition of DIXDC1 by microRNA-1271 suppresses the proliferation and invasion of prostate cancer cells., PMID:28153722
Expression of Dixdc1 and its Role in Astrocyte Proliferation after Traumatic Brain Injury., PMID:27873129
DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants., PMID:27829159
Knockdown of DIXDC1 Inhibits the Proliferation and Migration of Human Glioma Cells., PMID:27817168
DIXDC1 promotes tumor proliferation and cell adhesion mediated drug resistance (CAM-DR) via enhancing p-Akt in Non-Hodgkin's lymphomas., PMID:27701018
Overexpression of DIXDC1 correlates with enhanced cell growth and poor prognosis in human pancreatic ductal adenocarcinoma., PMID:27498060
DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling., PMID:27752079
Dixdc1 targets CyclinD1 and p21 via PI3K pathway activation to promote Schwann cell proliferation after sciatic nerve crush., PMID:27521891
Downregulated expression of DIXDC1 in hepatocellular carcinoma and its correlation with prognosis., PMID:27468723
Inhibition of β-catenin signaling protects against CTGF-induced alveolar and vascular pathology in neonatal mouse lung., PMID:26991260
A Tale of the Good and Bad: Remodeling of the Microtubule Network in the Brain by Cdk5., PMID:26944284
DIXDC1 activates the Wnt signaling pathway and promotes gastric cancer cell invasion and metastasis., PMID:25648220
An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential., PMID:25042806
DIXDC1 increases the invasion and migration ability of non-small-cell lung cancer cells via the PI3K-AKT/AP-1 pathway., PMID:23813858
Huaier aqueous extract inhibits ovarian cancer cell motility via the AKT/GSK3β/β-catenin pathway., PMID:23667667
Therapeutic effects of microRNA-582-5p and -3p on the inhibition of bladder cancer progression., PMID:23295946
Crystallographic characterization of the DIX domain of the Wnt signalling positive regulator Ccd1., PMID:21795788
Elevation of WNT5A expression in polyp formation in Lkb1+/- mice and Peutz-Jeghers syndrome., PMID:21341271
DISC1-binding proteins in neural development, signalling and schizophrenia., PMID:21195721
Abnormal behavior in mice mutant for the Disc1 binding partner, Dixdc1., PMID:22832659
Molecular basis of Wnt activation via the DIX domain protein Ccd1., PMID:21189423
Switching DISC1 function in neurogenesis: Dixdc1 selects DISC1 binding partners., PMID:20643344
Dixdc1 is a critical regulator of DISC1 and embryonic cortical development., PMID:20624590
Wnt signaling stabilizes the DIXDC1 protein through decreased ubiquitin-dependent degradation., PMID:20085589
DIXDC1 targets p21 and cyclin D1 via PI3K pathway activation to promote colon cancer cell proliferation., PMID:19572978
A novel monoclonal antibody specific to DIXDC1 protein., PMID:19519246
DIXDC1 co-localizes and interacts with gamma-tubulin in HEK293 cells., PMID:19375513
DIXDC1 promotes retinoic acid-induced neuronal differentiation and inhibits gliogenesis in P19 cells., PMID:18629627
Dynamic recruitment of axin by Dishevelled protein assemblies., PMID:17606995
Crystallization and preliminary X-ray crystallographic studies of the axin DIX domain., PMID:17554179
DIXDC1 isoform, l-DIXDC1, is a novel filamentous actin-binding protein., PMID:16814745
Expression of mouse Coiled-coil-DIX1 (Ccd1), a positive regulator of Wnt signaling, during embryonic development., PMID:16378754
For research use only. Not for human or drug use.
