Catalog No.
YHH11501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gln143
Predicted molecular weight
18.71 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15506
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CT22, SPA17, Sp17-1, SP17, Cancer/testis antigen 22, Sperm surface protein Sp17, Sperm autoantigenic protein 17, Sperm protein 17
Whole-genome bisulfite sequencing of X and Y sperm in Holstein bulls reveals differences in autosomal methylation status., PMID:40119264
Decreased AKAP4/PKA signaling pathway in high DFI sperm affects sperm capacitation., PMID:37695244
Sperm protein antigen 17 and Sperm flagellar 1 cancer testis antigens are expressed in a rare case of ciliated foregut cyst of the common hepatic duct., PMID:37224658
A Comparative Cross-Platform Analysis to Identify Potential Biomarker Genes for Evaluation of Teratozoospermia and Azoospermia., PMID:36292606
Quantitative phosphoproteomics analyses reveal the regulatory mechanisms related to frozen-thawed sperm capacitation and acrosome reaction in yak (Bos grunniens)., PMID:36277216
ANXA2, SP17, SERPINA5, PRDX2 genes, and sperm DNA fragmentation differentially represented in male partners of infertile couples with normal and abnormal sperm parameters., PMID:36177795
Sperm Autoantigenic Protein 17 Predicts the Prognosis and the Immunotherapy Response of Cancers: A Pan-Cancer Analysis., PMID:35592314
Bull Sperm Capacitation Is Accompanied by Redox Modifications of Proteins., PMID:34360666
Beyond PKA: Evolutionary and structural insights that define a docking and dimerization domain superfamily., PMID:34256050
Identification of new biomarkers in immune microenvironment of testicular germ cell tumour., PMID:33544925
Gene Co-expression Network Analysis for Identifying Modules and Functionally Enriched Pathways in Vitiligo Disease: A Systems Biology Study., PMID:33463119
Serum Sp17 Autoantibody Serves as a Potential Specific Biomarker in Patients with SAPHO Syndrome., PMID:33392854
Immunogenicity and contraceptive efficacy of recombinant fusion protein encompassing Sp17 spermatozoa-specific protein and GnRH: Relevance of adjuvants and microparticles based delivery to minimize number of injections., PMID:31845450
Effect of Antioxidant Supplementation on the Sperm Proteome of Idiopathic Infertile Men., PMID:31623114
Genome-wide association study for age at puberty in young Nelore bulls., PMID:31515857
Sperm Protein Antigen 17 Expression Correlates With Lymph Node Metastasis and Worse Overall Survival in Patients With Breast Cancer., PMID:31417875
Sperm Proteome Analysis and Identification of Fertility-Associated Biomarkers in Unexplained Male Infertility., PMID:31336797
Cancer-testis antigens as biomarkers for Merkel cell carcinoma: Pitfalls and opportunities., PMID:31218705
Validity and prognostic significance of sperm protein 17 as a tumor biomarker for epithelial ovarian cancer: a retrospective study., PMID:30309325
Oligopeptides for Immunotherapy Approaches in Ovarian Cancer Treatment., PMID:29793409
Proteomic Signatures of Sperm Mitochondria in Varicocele: Clinical Use as Biomarkers of Varicocele Associated Infertility., PMID:29530785
Development of a M cell-targeted microparticulate platform, BSK02™, for oral immunization against the ovarian cancer antigen, sperm protein 17., PMID:29504239
Treatment of semen samples with α-chymotrypsin alters the expression pattern of sperm functional proteins-a pilot study., PMID:29409138
[Association study of genetic markers of schizophrenia and its cognitive endophenotypes]., PMID:29372809
Towards the identification of reliable sperm biomarkers for male infertility: A sperm proteomic approach., PMID:29205438
Novel Sperm and Gonadotropin-releasing Hormone-based Recombinant Fusion Protein: Achievement of 100% Contraceptive Efficacy by Co-immunization of Male and Female Mice., PMID:27676172
In Vitro Assessment of the Expression and T Cell Immunogenicity of the Tumor-Associated Antigens BORIS, MUC1, hTERT, MAGE-A3 and Sp17 in Uterine Cancer., PMID:27618037
Umbilical cord blood-derived dendritic cells infected by adenovirus for SP17 expression induce antigen-specific cytotoxic T cells against NSCLC cells., PMID:26300426
Mapping T and B cell epitopes in sperm protein 17 to support the development of an ovarian cancer vaccine., PMID:26263201
Novel antigens in non-small cell lung cancer: SP17, AKAP4, and PTTG1 are potential immunotherapeutic targets., PMID:25739119
Sperm protein 17 and AKAP-associated sperm protein cancer/testis antigens are expressed in ciliated hepatic foregut cysts., PMID:25600306
Increased levels of sperm protein 17 mRNA and circulating antibodies in periampullary carcinoma patients., PMID:25348194
Sperm protein 17 is an oncofetal antigen: a lesson from a murine model., PMID:24811209
Analysis of GAGE, NY-ESO-1 and SP17 cancer/testis antigen expression in early stage non-small cell lung carcinoma., PMID:24103781
Anti-Sp17 monoclonal antibody-doxorubicin conjugates as molecularly targeted chemotherapy for ovarian carcinoma., PMID:23943313
Sperm protein 17, MAGE-C1 and NY-ESO-1 in hepatocellular carcinoma: expression frequency and their correlation with clinical parameters., PMID:23923079
Translating sperm protein 17 as a target for immunotherapy from the bench to the bedside in the light of cancer complexity., PMID:23330722
Limited SP17 expression within tumors diminishes its therapeutic potential., PMID:23137323
Anti-Sp17 monoclonal antibody with antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity activities against human ovarian cancer cells., PMID:22198696
Sperm protein 17: clinical relevance of a cancer/testis antigen, from contraception to cancer immunotherapy, and beyond., PMID:21557640
Prospects and challenges for immunotherapy of ovarian cancer--what can we learn from the tumor microenvironment?, PMID:21557634
In vivo molecular targeting effects of anti-Sp17- ICG-Der-02 on hepatocellular carcinoma evaluated by an optical imaging system., PMID:21366930
Potential target antigens for a universal vaccine in epithelial ovarian cancer., PMID:20885926
Sperm protein 17 is highly expressed in endometrial and cervical cancers., PMID:20712874
[Biological activity assays and cellular imaging of anti-human sperm protein 17 immunomagnetic nanoparticles]., PMID:19900363
Overexpression of human sperm protein 17 increases migration and decreases the chemosensitivity of human epithelial ovarian cancer cells., PMID:19744347
Sperm protein 17 is a novel marker for predicting cisplatin response in esophageal squamous cancer cell lines., PMID:19685492
Sperm protein 17 is expressed in the sperm fibrous sheath., PMID:19604394
[Aberrant expression of sperm protein 17 enhances migration of ovarian cancer cell line HO-8910]., PMID:19102497
For research use only. Not for human or drug use.
