Catalog No.
YHH11201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr47-Asn300
Predicted molecular weight
30.00 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15485
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hucolin, FCNL, Collagen/fibrinogen domain-containing protein 2, 37 kDa elastin-binding protein, Serum lectin p35, Ficolin-2, EBP-37, FCN2, Ficolin-beta, L-ficolin, Ficolin-B
Proteins associated with rehospitalization, mortality and diuretic resistance in acutely decompensated heart failure., PMID:40504107
Potential diagnostic marker gene set for non-alcoholic steatohepatitis associated hepatocellular carcinoma with lymphocyte infiltration., PMID:40386252
Species differences in opsonization and phagocyte recognition of preclinical poly-2-alkyl-2-oxazoline-coated nanoparticles., PMID:40102395
Identification of Cardiometabolic Protein Biomarkers for Acute Myocardial Infarction Using Olink Proteomics., PMID:40013238
Novel plasma biomarkers of amyloid plaque pathology and cortical thickness: Evaluation of the NULISA targeted proteomic platform in an ethnically diverse cohort., PMID:39989429
Proteomics Analysis of Five Potential Plasma-derived Exosomal Biomarkers for Acute Myocardial Infarction., PMID:39754756
[Effect of FCN gene single nucleotide polymorphism on the susceptibility of pre-eclampsia in Han nationality pregnant women]., PMID:39581768
Unveiling ficolins: diagnostic and prognostic biomarkers linked to the Tumor Microenvironment in Lung Cancer., PMID:39390580
Inflammatory proteins associated with Alzheimer's disease reduced by a GLP1 receptor agonist: a post hoc analysis of the EXSCEL randomized placebo controlled trial., PMID:39358806
Machine learning approach to predict blood-secretory proteins and potential biomarkers for liver cancer using omics data., PMID:39216516
Identification of Hub Genes in Liver Hepatocellular Carcinoma Based on Weighted Gene Co-expression Network Analysis., PMID:38683466
Genetic insight into putative causes of xanthelasma palpebrarum: a Mendelian randomization study., PMID:38601164
Construction and validation of a joint diagnosis model based on random forest and artificial intelligence network for hepatitis B-related hepatocellular carcinoma., PMID:38482416
Ficolin-A/2 Aggravates Severe Lung Injury through Neutrophil Extracellular Traps Mediated by Gasdermin D-Induced Pyroptosis., PMID:38442803
Variants of IL6, IL10, FCN2, RNASE3, IL12B and IL17B loci are associated with Schistosoma mansoni worm burden in the Albert Nile region of Uganda., PMID:38033168
Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis., PMID:37903821
A genome-wide association scan reveals novel loci for facial traits of Koreans., PMID:37734486
Selected SNPs of FCN2 Associated with Chronic Tonsillitis in the Polish Adult Population., PMID:36833169
Association of low ficolin-2 concentration in cord serum with respiratory distress syndrome in preterm newborns., PMID:36733481
Association of the FCN2 Gene Promoter Region Polymorphisms with Very Low Birthweight in Preterm Neonates., PMID:36499663
Ficolin-2: A potential immune-related therapeutic target with low expression in liver cancer., PMID:36425563
A mechanistic framework for cardiometabolic and coronary artery diseases., PMID:36276926
Comprehensive Analysis of Prognostic Value and Immune Infiltration of Ficolin Family Members in Hepatocellular Carcinoma., PMID:35928441
The adverse inflammatory response of tobacco smoking in COVID-19 patients: biomarkers from proteomics and metabolomics., PMID:35772384
Ficolin-2 Plasma Level Assesses Liver Fibrosis in Non-Alcoholic Fatty Liver Disease., PMID:35269955
Lectin and alternative complement pathway activation in cutaneous manifestations of IgA-vasculitis: A new target for therapy?, PMID:35121432
Comprehensive mass spectrometry for development of proteomic biomarkers of intracranial aneurysms., PMID:34973552
Polymorphisms of the FCN2 Gene 3'UTR Region and Their Clinical Associations in Preterm Newborns., PMID:34777352
Novel FCN2 Variants and Haplotypes are Associated with Rheumatic Heart Disease., PMID:34529517
Plasma Proteomic Biomarkers Relating to Alzheimer's Disease: A Meta-Analysis Based on Our Own Studies., PMID:34366831
Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins., PMID:34290717
Identification and Validation of Hub Genes Associated With Hepatocellular Carcinoma Via Integrated Bioinformatics Analysis., PMID:34277395
Hepatitis B Virus Infection Among Leprosy Patients: A Case for Polymorphisms Compromising Activation of the Lectin Pathway and Complement Receptors., PMID:33643280
PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells., PMID:33446637
Genes and SNPs in the pathway of immune response and caries risk: a systematic review and meta-analysis., PMID:33327793
Characterization of differentially expressed plasma proteins in patients with acute myocardial infarction., PMID:32736138
Proteomic changes in intracranial blood during human ischemic stroke., PMID:32641418
A novel urinary biomarker protein panel to identify children with ureteropelvic junction obstruction - A pilot study., PMID:32620509
Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults., PMID:32601370
iTRAQ-based proteomic analysis reveals potential serum biomarkers of allergic and nonallergic asthma., PMID:32424932
Association of FCN2 polymorphisms and Ficolin-2 levels with dengue fever in Vietnamese patients., PMID:32088336
Associations of Ficolins With Hematological Malignancies in Patients Receiving High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantations., PMID:32047495
Modulation of plasma protein expression in bullfrog (Rana catesbeiana) tadpoles during seasonal acclimatization and thermal acclimation., PMID:31987871
Association of ficolin-2 gene polymorphisms and susceptibility to systemic lupus erythematosus in Egyptian children and adolescents: a multicenter study., PMID:31184250
Complement proteins regulating macrophage polarisation on biomaterials., PMID:31128512
A Rare Genetic Defect of MBL2 Increased the Risk for Progression of IgA Nephropathy., PMID:30967869
Role of lectin pathway complement proteins and genetic variants in organ damage and disease severity of systemic sclerosis: a cross-sectional study., PMID:30885245
Serum Proteomic Changes as Candidate Biomarkers of Intermediate Liver Fibrosis in Chronic Hepatitis B Infection., PMID:30883302
Association of ficolin-2 (FCN2) functional polymorphisms and protein levels with rheumatic fever and rheumatic heart disease: relationship with cardiac function., PMID:30775605
Expression of human ficolin-2 in hepatocytes confers resistance to infection by diverse hepatotropic viruses., PMID:30747617