Catalog No.
YHH06301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg403-Met499
Predicted molecular weight
13.79 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15311
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dinitrophenyl S-glutathione ATPase, RLIP1, RalBP1, DNP-SG ATPase, 76 kDa Ral-interacting protein, Ral-interacting protein 1, RalA-binding protein 1, RLIP76, RALBP1
Discovery of a novel quinoline RIP1 inhibitor and its treatment of acute liver injury in mice., PMID:40088687
ALKBH5 suppresses gastric cancer tumorigenesis and metastasis by inhibiting the translation of uncapped WRAP53 RNA isoforms in an m6A-dependent manner., PMID:39815301
Rlip76 in ageing and Alzheimer's disease: Focus on oxidative stress and mitochondrial mechanisms., PMID:39617058
RIP1 inhibition reduces chondrocyte apoptosis through downregulating nuclear factor-kappa B signaling in a mouse osteoarthritis model., PMID:39514126
RIP1 inhibition protects retinal ganglion cells in glaucoma models of ocular injury., PMID:39448868
Identification and Functional Analysis of Ras-Related Associated with Diabetes Gene (rrad) in Edwardsiella piscicida-Resistant Individuals of Japanese Flounder (Paralichthys olivaceus)., PMID:39408905
Regulation of Drosophila brain development and organ growth by the Minibrain/Rala signaling network., PMID:39271109
Enhancing carboplatin sensitivity in ovarian cancer cells by blocking the mercapturic acid pathway transporter., PMID:39051454
Ursolic acid improves necroptosis via STAT3 signaling in intestinal ischemia/reperfusion injury., PMID:38971110
A novel route of intercellular copper transport and detoxification in oyster hemocytes., PMID:38917627
Mifepristone protects acetaminophen induced liver injury through NRF2/GSH/GST mediated ferroptosis suppression., PMID:38906233
Regulation of brain development by the Minibrain/Rala signaling network., PMID:38766038
Electroacupuncture Inhibits Neuroinflammation Induced by Astrocytic Necroptosis Through RIP1/MLKL/TLR4 Pathway in a Mouse Model of Spinal Cord Injury., PMID:37982922
The role of RLIP76 in oxidative stress and mitochondrial dysfunction: Evidence based on autopsy brains from Alzheimer's disease patients., PMID:37926360
Abnormal interaction of Rlip with mutant APP/Abeta and phosphorylated tau reduces wild-type Rlip levels and disrupt Rlip function in Alzheimer's disease., PMID:37633469
A novel RIP1-mediated canonical WNT signaling pathway that promotes colorectal cancer metastasis via β -catenin stabilization-induced EMT., PMID:37500894
Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights., PMID:37371116
FOXO3 Deficiency in Neutrophils Drives Colonic Inflammation and Tumorigenesis., PMID:37298680
Rlip overexpression reduces oxidative stress and mitochondrial dysfunction in Alzheimer's disease: Mechanistic insights., PMID:37225106
MDR1 Inhibition Reverses Doxorubicin-Resistance in Six Doxorubicin-Resistant Canine Prostate and Bladder Cancer Cell Lines., PMID:37175843
XIAP deletion sensitizes mice to TNF-induced and RIP1-mediated death., PMID:37041175
Pharmacogenetics of the Primary and Metastatic Osteosarcoma: Gene Expression Profile Associated with Outcome., PMID:36982681
Rlip Protein: A Potential Target for COVID-19., PMID:36816155
Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module., PMID:36812304
Crucial Role of RLIP76 in Promoting Glycolysis and Tumorigenesis by Stabilization of HIF-1α in Glioma Cells Under Hypoxia., PMID:35998001
Liver X receptor agonists exert antitumor effects against hepatocellular carcinoma via inducing REPS2 expression., PMID:35995867
RILP inhibits proliferation, migration, and invasion of PC3 prostate cancer cells., PMID:35981451
Astrocyte-Derived TNF-α-Activated Platelets Promote Cerebral Ischemia/Reperfusion Injury by Regulating the RIP1/RIP3/AKT Signaling Pathway., PMID:35781632
Rlip76: An Unexplored Player in Neurodegeneration and Alzheimer's Disease?, PMID:35682775
The RAL Enigma: Distinct Roles of RALA and RALB in Cancer., PMID:35626682
CDDO-Me Attenuates CA1 Neuronal Death by Facilitating RalBP1-Mediated Mitochondrial Fission and 4-HNE Efflux in the Rat Hippocampus Following Status Epilepticus., PMID:35624848
The ABCB1, ABCC2 and RALBP1 polymorphisms are associated with carbamazepine response in epileptic patient: a systematic review., PMID:35325436
Rlip Depletion Alters Oncogene Transcription at Multiple Distinct Regulatory Levels., PMID:35158795
Identification of key candidate genes and pathways associated with colorectal aberrant crypt foci-to-adenoma-to-carcinoma progression., PMID:35154601
Anagliptin prevents lipopolysaccharide (LPS)- induced inflammation and activation of macrophages., PMID:35045357
Receptor Interacting Protein Kinase Pathways Regulate Innate B Cell Developmental Checkpoints But Not Effector Function in Mice., PMID:34956189
Bcl-3 promotes TNF-induced hepatocyte apoptosis by regulating the deubiquitination of RIP1., PMID:34853447
RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer's Disease., PMID:34831336
Relevance of NR1I2 variants on carbamazepine therapy in Mexican Mestizos with epilepsy at a tertiary-care hospital., PMID:34612084
Coeloglossum viride var. bracteatum extract attenuates Aβ-induced toxicity by inhibiting RIP1-driven inflammation and necroptosis., PMID:34506939
Inhibition of neuronal necroptosis mediated by RIP1/RIP3/MLKL provides neuroprotective effects on kaolin-induced hydrocephalus in mice., PMID:34374150
Haploinsufficiency Interactions between RALBP1 and p53 in ERBB2 and PyVT Models of Mouse Mammary Carcinogenesis., PMID:34283045
Acrolein but not its metabolite, 3-Hydroxypropylmercapturic acid (3HPMA), activates vascular transient receptor potential Ankyrin-1 (TRPA1): Physiological to toxicological implications., PMID:34271065
Discovery of a Necroptosis Inhibitor Improving Dopaminergic Neuronal Loss after MPTP Exposure in Mice., PMID:34069782
RLIP76: A Structural and Functional Triumvirate., PMID:34064388
Parallel Rap1>RalGEF>Ral and Ras signals sculpt the C. elegans nervous system., PMID:33991533
Casp8 acts through A20 to inhibit PD-L1 expression: The mechanism and its implication in immunotherapy., PMID:33934451
TNF-α Triggers RIP1/FADD/Caspase-8-Mediated Apoptosis of Astrocytes and RIP3/MLKL-Mediated Necroptosis of Neurons Induced by Angiostrongylus cantonensis Infection., PMID:33683530
5-((7-Chloro-6-fluoro-1h-indol-3-yl) methyl)-3-methylimidazolidine-2,4-dione as a RIP1 inhibitor protects LPS/D-galactosamine-induced liver failure., PMID:33662432
Effects of Hsp90 inhibitor on the RIP1-RIP3-MLKL pathway during the development of heart failure in mice., PMID:33640405
For research use only. Not for human or drug use.
