Catalog No.
YHH03301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp175-Pro400
Predicted molecular weight
28.70 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15149
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PLEC1, HD1, Hemidesmosomal protein 1, Plectin, Plectin-1, PLTN, PLEC, PCN
Correlation of plasma plectin levels with small intracranial aneurysms instability and prognosis., PMID:40375046
Exome sequencing reveals low-frequency and rare variant contributions to multiple sclerosis susceptibility in Turkish families., PMID:40188234
Molecular mimicry-driven autoimmunity in chronic rhinosinusitis with nasal polyps., PMID:39984131
Blood biomarker fingerprints in a cohort of patients with CHRNE-related congenital myasthenic syndrome., PMID:39948634
Plectin, a novel regulator in migration, invasion and adhesion of ovarian cancer., PMID:39915800
Loss of Glutathione-S-Transferase Theta 2 (GSTT2) Modulates the Tumor Microenvironment and Response to BCG Immunotherapy in a Murine Orthotopic Model of Bladder Cancer., PMID:39769061
Epoxy metabolites of linoleic acid promote the development of breast cancer via orchestrating PLEC/NFκB1/CXCL9-mediated tumor growth and metastasis., PMID:39695149
Plakin Expression in Serous Epithelial Ovarian Cancer Has the Potential to Impede Metastatic Spread and Epithelial-Mesenchymal Transition: A Comparative Expression Analysis of Immunohistochemical and In Silico Datasets., PMID:39682273
The genetic architecture of hip shape and its role in the development of hip osteoarthritis and fracture., PMID:39574169
Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits., PMID:39537608
ΔNp63α promotes radioresistance in esophageal squamous cell carcinoma through the PLEC-KEAP1-NRF2 feedback loop., PMID:39500864
Exploring novel natural compound-based therapies for Duchenne muscular dystrophy management: insights from network pharmacology, QSAR modeling, molecular dynamics, and free energy calculations., PMID:39415830
Data-augmented machine learning scoring functions for virtual screening of YTHDF1 m6A reader protein., PMID:39405731
Plectin: Dual Participation in Tumor Progression., PMID:39334817
ITGB4-Related pyloric atresia without epidermolysis in two siblings., PMID:39322060
Plectin-1-targeted recognition for enhancing comprehensive therapy in pancreatic ductal adenocarcinoma., PMID:39291372
Novel PLEC variants associated with infantile cholestasis., PMID:39168815
Machine learning-based identification of biomarkers and drugs in immunologically cold and hot pancreatic adenocarcinomas., PMID:39152432
Integrative analysis of transcriptome-wide association study and mRNA expression profile identified risk genes for bipolar disorder., PMID:39151574
Genetics of Cardiac Aging Implicate Organ-Specific Variation., PMID:39148824
Identification of Pathogenic Pathways for Recurrence of Focal Segmental Glomerulosclerosis after Kidney Transplantation., PMID:39125467
Association of R-loop binding proteins with prognosis and anti-tumor drug sensitivity in lung adenocarcinoma: a bioinfor-matic study., PMID:39044569
Loss of cell junctional components and matrix alterations drive cell desquamation and fibrotic changes in Idiopathic Pulmonary Fibrosis., PMID:38948715
Homozygosity for a Rare Plec Variant Suggests a Contributory Role in Congenital Insensitivity to Pain., PMID:38928066
Protein interactome analysis of ATP1B1 in alveolar epithelial cells using Co-Immunoprecipitation mass spectrometry and parallel reaction monitoring assay., PMID:38912441
Expanding the Clinical Phenotype of PLECTIN-Related Plectinopathies., PMID:38912134
Identification of the cytoplasmic DNA-Sensing cGAS-STING pathway-mediated gene signatures and molecular subtypes in prostate cancer., PMID:38877472
Deletion of Tmem268 in mice suppresses anti-infectious immune responses by downregulating CD11b signaling., PMID:38730209
DOTA-Based Plectin-1 Targeted Contrast Agent Enables Detection of Pancreatic Cancer in Human Tissue., PMID:38608197
Comprehensive machine learning boosts structure-based virtual screening for PARP1 inhibitors., PMID:38582911
Genetic architecture of the structural connectome., PMID:38438384
HSPB1 as an RNA-binding protein mediates the pathological process of osteoarthritis., PMID:38429742
Failure of cholic acid therapy in a child with a bile acid synthesis defect and harboring plectin mutations., PMID:38426803
Advantages of whole-exome sequencing over immunomapping in 67 Brazilian patients with epidermolysis bullosa., PMID:38368142
[Plectin Promotes the Migration of Hepatocellular Carcinoma Cells Through Inducing F-actin Polymerization]., PMID:38322534
Bioinformatics analysis of a disease-specific lncRNA-miRNA-mRNA regulatory network in recurrent spontaneous abortion (RSA)., PMID:38310583
Plectin plays a role in the migration and volume regulation of astrocytes: a potential biomarker of glioblastoma., PMID:38263015
Identification of AGO2 and PLEC genes polymorphisms in Hu sheep and their relationship with body size traits., PMID:38149679
Phosphatase to kinase switch of a critical enzyme contributes to timing of cell differentiation., PMID:38055339
Plectin Deficiency in Fibroblasts Deranges Intermediate Filament and Organelle Morphology, Migration, and Adhesion., PMID:37716646
Role of plectin and its interacting molecules in cancer., PMID:37632650
Novel biallelic variants in the PLEC gene are associated with severe hearing loss., PMID:37393735
Joint analysis of WES and RNA-Seq identify signature genes related to metastasis in prostate cancer., PMID:37378426
Identification of Somatic Mutations in Plasma Cell-Free DNA from Patients with Metastatic Oral Squamous Cell Carcinoma., PMID:37373553
[Clinicopathological and gene mutation characteristics of uterine carcinosarcoma]., PMID:37357193
The Versatility of Plectin in Cancer: A Pan-Cancer Analysis on Potential Diagnostic and Prognostic Impacts of Plectin Isoforms., PMID:37262182
Transcriptome Analysis Reveals the Age-Related Developmental Dynamics Pattern of the Longissimus Dorsi Muscle in Ningxiang Pigs., PMID:37239410
Asparagine Uptake: a Cellular Strategy of Methylocystis to Combat Severe Salt Stress., PMID:37184406
Z-Disk-Associated Plectin (Isoform 1d): Spatial Arrangement, Interaction Partners, and Role in Filamin C Homeostasis., PMID:37174658
Inflammatory Response and Exosome Biogenesis of Choroid Plexus Organoids Derived from Human Pluripotent Stem Cells., PMID:37108817
For research use only. Not for human or drug use.
