Catalog No.
YHG89401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Pro272
Predicted molecular weight
33.29 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q14764
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
LRP, Major vault protein, Lung resistance-related protein, MVP
Proteomic analysis reveals modulation of key proteins in follicular thyroid cancer progression., PMID:40394764
Quantitative Proteomic Analysis of Cardiac Xenograft Failure in a Pig-to-Non-Human Primate Model Identifies NF-κB as a Critical Immunomodulatory Target., PMID:40375624
Identification of a Biomarker Panel in Extracellular Vesicles Derived From Non-Small Cell Lung Cancer (NSCLC) Through Proteomic Analysis and Machine Learning., PMID:40366616
Endothelial major vault protein alleviates vascular remodeling via promoting Parkin-mediated mitophagy., PMID:40348769
Intercellular contractile force attenuates chemosensitivity through Notch-MVP-mediated nuclear drug export., PMID:40333760
Genome-wide association study and multi-ancestry meta-analysis identify common variants associated with carotid artery intima-media thickness., PMID:40321265
Discovery of novel ancestry specific genes for androgens and hypogonadism in Million Veteran Program Men., PMID:40316537
Comprehensive genetic analysis based on multi - omics reveals novel therapeutic targets for mitral valve prolapse and drug molecular dynamics simulation., PMID:40311696
MVP-LCN2 axis triggers evasion of ferroptosis to drive hepatocarcinogenesis and sorafenib resistance., PMID:40262414
Soluble Guanylate Cyclase Stimulator, BAY41-8543: A Promising Approach for the Treatment of Chronic Heart Failure Caused by Pressure and Volume Overload., PMID:40159447
Whole exome sequencing of 80 cases of sporadic mitral valve prolapse reveals novel disease-associated genes and variants in a Southern Chinese population., PMID:40131712
Mesenchymal Stem Cells and Fibroblasts Contribute to Microvascular Proliferation in Glioblastoma and are Correlated with Immunosuppression and Poor Outcome., PMID:40131028
Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk., PMID:40119478
Notch1 and Major Vault Proteins Modulate Temozolomide Resistance in Glioblastoma., PMID:40100070
Development and application of multivalent nanobody-functionalized plasmonic probes in SERS sensing platforms., PMID:40023071
Integrating fragment-based screening with targeted protein degradation and genetic rescue to explore eIF4E function., PMID:40016190
Vault Particles in Cancer Progression, Multidrug Resistance, and Drug Delivery: Current Insights and Future Applications., PMID:40004027
An endothelial SOX18-mevalonate pathway axis enables repurposing of statins for infantile hemangioma., PMID:39998898
ENDOGLIN (CD105): A marker of tumour vasculature for assessment of malignant potential of oral submucous fibrosis., PMID:39949694
Large-scale multi-omics identifies drug targets for heart failure with reduced and preserved ejection fraction., PMID:39915329
Optimization on cell lysis and capture process of human adenovirus type 5 produced in suspension HEK293 cells., PMID:39914788
Mitral Valve Prolapse Caused by TLL1 Gain-of-Function Mutation., PMID:39880331
Investigation of Genomic and Transcriptomic Risk Factors of Clopidogrel Response in African Americans., PMID:39868839
Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosis., PMID:39794479
Synthetic inhibition of SREBP2 and the mevalonate pathway blocks rhabdomyosarcoma tumor growth in vitro and in vivo and promotes chemosensitization., PMID:39706565
LRH-1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype., PMID:39702941
Curation and validation of electronic medical record-based dementia diagnoses in the VA Million Veteran Program., PMID:39692476
Oral Health, Inflammation, and Cardiometabolic Factors in the VA Million Veteran Program., PMID:39629945
Exploring the role of vault complex in the nervous system: a literature review., PMID:39584466
Optimizing Anti-Myelin-Associated Glycoprotein and IgM-Gammopathy Testing for Neuropathy Treatment Evaluation., PMID:39499873
Isolated prolapse of the posterior mitral valve leaflet: phenotypic refinement, heritability and genetic etiology., PMID:39484266
Interleukin-6, C-Reactive Protein, and Recurrence After Stroke: A Time-Course Analysis of Individual-Participant Data., PMID:39479747
Proteomic Analysis of Microsomal Proteins Reveals That MVP Is Crucial for the Secretion of GDF-15, Which in Turn Promotes the Neuroendocrine Differentiation of PCa Cells., PMID:39472282
GLP1R Gene Expression and Kidney Disease Progression., PMID:39453656
Reappraisal of prognostic factors in CNS WHO grade 3 oligodendrogliomas IDH-mutant and 1p/19q co-deleted: Lessons from the French POLA cohort., PMID:39432559
Mitral Annular Disjunction in Heritable Thoracic Aortic Disease: Insights From the Montalcino Aortic Consortium., PMID:39424426
Injury-induced myosin-specific tissue-resident memory T cells drive immune checkpoint inhibitor myocarditis., PMID:39378095
The major vault protein integrates adhesion-driven signals to regulate collagen remodeling., PMID:39368789
Identification of proteins associated with type 2 diabetes risk in diverse racial and ethnic populations., PMID:39349773
MiR-140-3p Improves Sensitivity to Docetaxel by Suppressing PD-L1/ABCG2/MVP Expression in Lung Adenocarcinoma., PMID:39348965
Cytolysin A is an intracellularly induced and secreted cytotoxin of typhoidal Salmonella., PMID:39341826
Major Vault Protein/Lung Resistance-Related Protein: A Novel Biomarker for Inflammation and Acute Infections., PMID:39338437
A case of the effective inhalation of nitric oxide therapy for caused severe pulmonary hypertension with protamine neutralization of systemic heparinization during totally endoscopic minimally invasive cardiac surgery., PMID:39303134
Significance of Fibrillin-1, Filamin A, MMP2 and SOX9 in Mitral Valve Pathology., PMID:39273357
Role of the X Chromosome in Alzheimer Disease Genetics., PMID:39250132
Perioperative changes in plasma cardiac troponin I concentration during mitral valvuloplasty for severe mitral regurgitation in dogs., PMID:39175974
MVP enhances FGF21-induced ferroptosis in hepatocellular carcinoma by increasing lipid peroxidation through regulation of NOX4., PMID:39143889
Major vault protein directly enhances adaptive immunity induced by Influenza A virus or indirectly through innate immunity., PMID:39069011
Unraveling the role of Major Vault Protein as a novel immune-related biomarker that promotes the proliferation and migration in pancreatic adenocarcinoma., PMID:39026679
Novel Vpx virus-like particles to improve cytarabine treatment response against acute myeloid leukemia., PMID:39003408
For research use only. Not for human or drug use.
