Catalog No.
YHG70501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly1107-Gly1373
Predicted molecular weight
32.39 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q14112
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Osteonidogen, NID-2, Nidogen-2, NID2
Subcutaneous Adipose Tissue-Secreted Proteins as Endocrine Regulators of Physical and Cognitive Function in Older Adults., PMID:40502786
NID2 Affects Prognosis of Glioma via Activating the Akt Signaling Pathway., PMID:40332526
Comprehensive analysis of blood proteome response to necrotic enteritis in broiler chicken., PMID:40275387
Nidogen 2 Overexpression Promotes Hepatosteatosis and Atherosclerosis., PMID:39684493
N-myc and STAT interactor degrades interferon regulatory factor 7 mediated type I interferon signaling to promote duck Tembusu virus replication., PMID:39270481
Extracellular Matrix Protein Signatures of the Outer and Inner Zones of the Rat Adrenal Cortex., PMID:39018382
Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response., PMID:38959305
Association of NID2 SNPs with Glioma Risk and Prognosis in the Chinese Population., PMID:38935278
Serum proteomic biomarker investigation of vascular depression using data-independent acquisition: a pilot study., PMID:38384936
Low-dose Bisphenol A exposure alters the functionality and cellular environment in a human cardiomyocyte model., PMID:37567409
Intercellular communication involving macrophages at the maternal-fetal interface may be a pivotal mechanism of URSA: a novel discovery from transcriptomic data., PMID:37265689
Expression of Genes Associated With Epithelial-Mesenchymal Transition in Merkel Cell Polyomavirus-Negative Merkel Cell Carcinoma., PMID:37207705
Construction of the Interaction Network of Hub Genes in the Progression of Barrett's Esophagus to Esophageal Adenocarcinoma., PMID:37077220
Genomic and transcriptomic analyses enable the identification of important genes associated with subcutaneous fat deposition in Holstein cows., PMID:36738887
Nidogen-2 is a Novel Endogenous Ligand of LGR4 to Inhibit Vascular Calcification., PMID:36354004
The potential of miR-153 as aggressive prostate cancer biomarker., PMID:36329790
What Do the Transcriptome and Proteome of Menstrual Blood-Derived Mesenchymal Stem Cells Tell Us about Endometriosis?, PMID:36232817
Comprehensive analysis of tissue proteomics in patients with papillary thyroid microcarcinoma uncovers the underlying mechanism of lymph node metastasis and its significant sex disparities., PMID:36106120
Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2., PMID:36007682
Rare Variant Analysis and Molecular Dynamics Simulation in Alzheimer's Disease Identifies Exonic Variants in FLG., PMID:35627223
Shared genetic loci for body fat storage and adipocyte lipolysis in humans., PMID:35256633
Genetic Regulation of DNA Methylation Yields Novel Discoveries in GWAS of Colorectal Cancer., PMID:35247911
Evaluation of DNA methylation in promoter regions of hTERT, TWIST1, VIM and NID2 genes in Moroccan bladder cancer patients., PMID:34922269
Nidogen-2: A new biomarker in colon cancer patients., PMID:34593672
Nidogen-2 Maintains the Contractile Phenotype of Vascular Smooth Muscle Cells and Prevents Neointima Formation via Bridging Jagged1-Notch3 Signaling., PMID:34315224
Influence of photobiomodulation and vitamin D on osteoblastic differentiation of human periodontal ligament stem cells and bone-like tissue formation through enzymatic activity and gene expression., PMID:34233429
NMI Facilitates Influenza A Virus Infection by Promoting Degradation of IRF7 through TRIM21., PMID:33761305
Genome-Scale Analysis Identified NID2, SPARC, and MFAP2 as Prognosis Markers of Overall Survival in Gastric Cancer., PMID:33758160
Abnormal promoter DNA hypermethylation of the integrin, nidogen, and dystroglycan genes in breast cancer., PMID:33500458
COL3A1, COL6A3, and SERPINH1 Are Related to Glucocorticoid-Induced Osteoporosis Occurrence According to Integrated Bioinformatics Analysis., PMID:32999266
A pilot proteomic study with a prospective cohort suspected to develop preeclampsia., PMID:32472113
Perlecan Knockdown Significantly Alters Extracellular Matrix Composition and Organization During Cartilage Development., PMID:32381549
Evaluation of NID2 promoter methylation for screening of Oral squamous cell carcinoma., PMID:32171289
QM/MM computations reveal details of the acetyl-CoA synthase catalytic center., PMID:32135171
ITIH5 and ECRG4 DNA Methylation Biomarker Test (EI-BLA) for Urine-Based Non-Invasive Detection of Bladder Cancer., PMID:32046186
GWAS Identifies 44 Independent Associated Genomic Loci for Self-Reported Adult Hearing Difficulty in UK Biobank., PMID:31564434
Application of GLAD-PCR Assay for Study on DNA Methylation in Regulatory Regions of Some Tumor-Suppressor Genes in Lung Cancer., PMID:31526458
Matrisome Properties of Scaffolds Direct Fibroblasts in Idiopathic Pulmonary Fibrosis., PMID:31426504
NID2 can serve as a potential prognosis prediction biomarker and promotes the invasion and migration of gastric cancer., PMID:31362888
Global serum proteomic changes in water buffaloes infected with Fasciola gigantica., PMID:31159882
Integrated bioinformatics analysis reveals novel key biomarkers and potential candidate small molecule drugs in gastric cancer., PMID:30975489
Silencing NID2 by DNA Hypermethylation Promotes Lung Cancer., PMID:30826972
Matrix mineralization controls gene expression in osteoblastic cells., PMID:30193837
Discovery and development of differentially methylated regions in human papillomavirus-related oropharyngeal squamous cell carcinoma., PMID:30070359
Somatic mutations in specific and connected subpathways are associated with short neuroblastoma patients' survival and indicate proteins targetable at onset of disease., PMID:29992558
The more potential performance of nidogen 2 methylation by tissue or plasma DNA over brichoalveolar lavage DNA in diagnosis of nonsmall cell lung cancer., PMID:29970687
Methyl-CpG-binding protein 2 mediates antifibrotic effects in scleroderma fibroblasts., PMID:29760157
Post-translational modification of type IV collagen with 3-hydroxyproline affects its interactions with glycoprotein VI and nidogens 1 and 2., PMID:29491144
Elevated levels of serum nidogen-2 in esophageal squamous cell carcinoma., PMID:29278876
Evaluation of Serum Nidogen-2 as a Screening and Diagnostic Tool for Ovarian Cancer., PMID:29131023