Catalog No.
YHG62101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly54-Phe268
Predicted molecular weight
26.03 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13634
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CDH18, Cadherin-14, CDH14, Cadherin-18
Changes in the Immune Profile and Chromatin Accessibility of Peripheral Regulatory T Cells in Psoriasis Patients Before and After Treatment With Biologics., PMID:40269508
Phase I Study of the Mutant IDH1 Inhibitor Ivosidenib: Long-term Safety and Clinical Activity in Patients with Conventional Chondrosarcoma., PMID:40100120
Calcium-dependent adhesion protein CDH18, a potential biomarker for prognosis in uterine corpus endometrial carcinoma., PMID:40017628
Letetresgene Autoleucel in Advanced/Metastatic Myxoid/Round Cell Liposarcoma., PMID:39836945
Histology-Specific Clinical Trial of Lenvatinib and Pembrolizumab in Patients with Sarcoma., PMID:39405335
GDF-15 Predicts Epithelioid Hemangioendothelioma Aggressiveness and Is Downregulated by Sirolimus through ATF4/ATF5 Suppression., PMID:39283723
Proteomics and digital subtraction angiography approaches reveal CDH18 as a potential target for therapy of moyamoya disease., PMID:39238003
Cadherin-18 loss in prospermatogonia and spermatogonial stem cells enhances cell adhesion through a compensatory mechanism., PMID:39147719
ApoE4 dysregulation incites depressive symptoms and mitochondrial impairments in mice., PMID:38506067
MDM2-p53 in liposarcoma: The need for targeted therapies with novel mechanisms of action., PMID:38104352
A duodenal mucosa transcriptome study identified reduced expression of a novel gene CDH18 in celiac disease., PMID:37813809
Circulating tumor DNA analysis of the phase III VOYAGER trial: KIT mutational landscape and outcomes in patients with advanced gastrointestinal stromal tumor treated with avapritinib or regorafenib., PMID:37105265
Effect of COP1 in Promoting the Tumorigenesis of Gastric Cancer by Down-Regulation of CDH18 via PI3K/AKT Signal Pathway., PMID:37025097
Integrating Whole-Genome Resequencing and RNA Sequencing Data Reveals Selective Sweeps and Differentially Expressed Genes Related to Nervous System Changes in Luxi Gamecocks., PMID:36980855
Role of colony-stimulating factor 1 in the neoplastic process of tenosynovial giant cell tumor., PMID:36502356
Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma., PMID:35710741
Expression Profile and Prognostic Values of CDH Family Members in Lung Adenocarcinoma., PMID:35242247
CSF1 receptor inhibition of tenosynovial giant cell tumor using novel disease-specific MRI measures of tumor burden., PMID:35040698
Avapritinib Versus Regorafenib in Locally Advanced Unresectable or Metastatic GI Stromal Tumor: A Randomized, Open-Label Phase III Study., PMID:34343033
Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial., PMID:34236401
The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus., PMID:30852652
Importance of Cadherins Methylation in Ovarian Cancer: a Next Generation Sequencing Approach., PMID:30368729
Prenatal diagnosis of a familial 5p14.3-p14.1 deletion encompassing CDH18, CDH12, PMCHL1, PRDM9 and CDH10 in a fetus with congenital heart disease on prenatal ultrasound., PMID:30342662
Sex difference of mutation clonality in diffuse glioma evolution., PMID:30256978
A Novel Tumor-Suppressor, CDH18, Inhibits Glioma Cell Invasiveness Via UQCRC2 and Correlates with the Prognosis of Glioma Patients., PMID:30078018
PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence., PMID:29789718
Integrated analysis of gene expression and copy number variations in MET proto‑oncogene‑transformed human primary osteoblasts., PMID:29207108
A comprehensive analysis of adiponectin QTLs using SNP association, SNP cis-effects on peripheral blood gene expression and gene expression correlation identified novel metabolic syndrome (MetS) genes with potential role in carcinogenesis and systemic inflammation., PMID:23628382
Cadherins and neuropsychiatric disorders., PMID:22765916
Identification of candidate predisposing copy number variants in familial and early-onset colorectal cancer patients., PMID:21128281
[Expressions of cadherin molecules CDH18 and PCDH17 in human azoospermic testes]., PMID:20180417
Genetic changes in sporadic keratocystic odontogenic tumors (odontogenic keratocysts)., PMID:17525355
Expression analysis of SIX3 and SIX6 in human tissues reveals differences in expression and a novel correlation between the expression of SIX3 and the genes encoding isocitrate dehyhrogenase and cadherin 18., PMID:15953543
The human cadherin-10 gene: complete coding sequence, predominant expression in the brain, and mapping on chromosome 5p13-14., PMID:10386616
Biochemical characterization and functional analysis of two type II classic cadherins, cadherin-6 and -14, and comparison with E-cadherin., PMID:10207020
Identification of human cadherin-14, a novel neurally specific type II cadherin, by protein interaction cloning., PMID:9030594
For research use only. Not for human or drug use.
